Journal of Oral Medicine and Pain

  • 제36권2호
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  • Pages.131-137
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  • 2011
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  • 2288-9272(pISSN)
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  • 2383-8493(eISSN)
대한안면통증구강내과학회 (Korean Academy of Orofacial Pain and Oral Medicine)
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하악신경영역에서 전류인지역치를 이용한 정량적 감각신경 검사의 재현성 조사

Reliability of Quantitative Sensory Testing Using Current Perception Thresholds in the Mandibular Nerve Area

  • 최희훈 (단국대학교 치과대학 구강내과학교실.치의학연구소) ;
  • 김미은 (단국대학교 치과대학 구강내과학교실.치의학연구소) ;
  • 김기석 (단국대학교 치과대학 구강내과학교실.치의학연구소)
  • Choi, Hee-Hun (Department of Oral Medicine and Institute of Dental Science, School of Dentistry, Dankook University) ;
  • Kim, Mee-Eun (Department of Oral Medicine and Institute of Dental Science, School of Dentistry, Dankook University) ;
  • Kim, Ki-Suk (Department of Oral Medicine and Institute of Dental Science, School of Dentistry, Dankook University)
  • 투고 : 2011.02.22
  • 심사 : 2011.04.28
  • 발행 : 2011.06.30
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초록

신경 손상 정도를 평가하기 위한 정량적감각평가(Quantitative Sensory Testing, QST) 방법 중 하나인 전류인지역치(Current Perception Threshold, CPT) 검사는 비교적 짧은 시간 내에 3가지 감각신경, 2000 Hz(A${\beta}$ fiber), 250 Hz(A${\delta}$ fiber), 5 Hz(C fiber)에 대한 기능을 평가 할 수 있다고 알려져 있지만, 그 재현성에 대해서는 여전히 상반된 견해가 존재한다. 본 연구는 CPT 검사의 재현성을 확인하고, 재현성을 향상시키기 위한 방법을 모색하고자 하였다. 건강한 남성 지원자 10명(평균 22.4세)을 대상으로 3주 동안 1주일 간격으로 2명의 검사자가 하악신경 영역을 각각 좌우로 나누어 3회 측정하여 비교 하였다. 3주에 걸친 측정 실험에서 2000 Hz(A${\beta}$ fiber)의 CPT는 3회 모두 좌우 측정치가 차이를 보인 반면(p<0.05), 250Hz(A${\delta}$ fiber)는 1회만 유의한 차이를 보였고(p<0.05), 5 Hz(C fiber)는 유의한 차이를 보이지 않았다. 좌우를 나누어 3회의 실험을 비교했을 때 모든 신경 검사에서 첫 회의 CPT가 가장 낮았으며, 250 Hz(A${\delta}$ fiber)와 5 Hz(C fiber)의 CPT는 첫 번째 실험과 나머지 실험사이에 유의한 차이가 있었고(p<0.05), 두 번째 실험 이후로 유의한 차이가 없었다. 상기의 결과로 보아 2000 Hz(A${\beta}$ fiber)의 CPT를 이용한 좌우 신경의 기능 비교는 적절하지 않은 반면, 250 Hz(A${\delta}$ fiber)와 5 Hz(C fiber)에서는 좌우 비교가 가능할 것으로 생각된다. 또한 반복 측정을 통해 250 Hz(A${\delta}$ fiber)와 5 Hz(C fiber)의 CPT 검사의 재현성을 높일 수 있을 것으로 판단된다.

Current Perception Threshold (CPT) using Neurometer($Neurometer^{(R)}$ CPT/C) is thought as one of easy and noninvasive QST(qunatitative sensory testing) tools for A${\beta}$, A${\delta}$ and C fibers within a relatively short time. However, conflicts about its reliability still exist. This study aimed to evaluate the reliability of CPTs evaluation and find a way to increase its reliability. Two examiners separately tested CPTs at each side of the mandibluar nerve areas for ten healthy male adults (average age of 22.4 years) three times with an intervals of a week during three weeks. Mean CPTs were compared between the right and left sides of the mandibular nerve area and between the three examinations on the each side. While CPTs at 2000 Hz(A${\beta}$ fiber) showed statistically significant side differences in all three examinations (p<0.05), significant side difference was found in only one examination at 250 Hz(A${\delta}$ fiber) and no difference at 5 Hz(C fiber). Comparing CPTs on the each side of the mandibular nerve area, all examinations at all sensory nerve fibers showed the least CPTs at the 1st examinations. CPTs at 250 Hz(A${\delta}$ fiber) and 5 Hz(C fiber) were significantly different between the first and the following examinations (p<0.05) and there was no significant difference between 2nd and 3rd examinations. The results of this study indicated that CPTs at 250 Hz(A${\delta}$ fiber) and 5 Hz(C fiber) are reliable but CPTs at 2000 Hz(A${\beta}$ fiber) is not appropriate for evaluation of side differences in the mandibular nerve area. In addition, it is suggested that repeated examination be helpful to increase reliability of the CPT evaluation.

키워드

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