녹차의 항-당뇨 효과에 대한 메타회귀분석

Meta-regression analysis for anti-diabetic effect of green tea

  • 윤아름 (덕성여자대학교 정보통계학과) ;
  • 최기헌 (덕성여자대학교 정보통계학과)
  • Yun, A-Reum (Department of Information and Statistics, Duksung Womens University) ;
  • Choi, Ki-Heon (Department of Information and Statistics, Duksung Womens University)
  • 투고 : 2011.04.10
  • 심사 : 2011.07.04
  • 발행 : 2011.08.01

초록

본 연구는 메타분석을 이용하여 녹차를 투여한 당뇨 유발 쥐들의 체중과 혈액 내 혈당량, 총 콜레스테롤, 중성지방, 고농도지단백 콜레스테롤의 평균비교를 통해 녹차의 항-당뇨 효과에 대해 알아보고자 한다. 헤지의 표준화된 평균차에서 고정효과모형을 적용한 결과 체중은 통계적으로 유의한 증가를 보였으며, 혈액 내 혈당량과 중성지방은 통계적으로 유의한 감소를 보였다. 동질성 검정을 통해 이질성을 보인 모든 변수에 대해 랜덤효과모형을 적용시킨 결과 체중은 유의한 증가를 보였으며, 혈액 내 혈당량은 유의한 감소를 보였다. 또한 녹차의 투여기간이 변수에 영향을 미치는지 알아보기 위해 메타회귀분석을 실시한 결과 모든 변수에 대해 녹차의 투여기간이 유의하지 않았다.

The present study was carried out to summarize the effect of green tea in the diabetic rats by meta-analysis related studies. The association measure to test effect of green tea was Hedges' standardized mean difference. In this particular fixed effect model, body weight was significantly increased. Also, blood glucose, triglycerides were significantly decreased. In this case of heterogeneous variable, random effect model was applied. In this model, body weight was significantly increased. Also, blood glucose was significantly decreased in green tea treated group. According to the Meta-regression analysis, duration of injection was not significant for variables.

키워드

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