Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Malignant Sertoli cell tumor in Shih Tzu dog

  • Kang, Sang-Chul (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Yang, Hyoung-Seok (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jung, Ji-Youl (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jung, Eun-Hye (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Lee, Hee-Chun (College of Veterinary Medicine, Gyeongsang National University) ;
  • Hwang, Eui-Kyung (College of Life Science and Natural Resources, Sangji University) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • Accepted : 2010.11.25
  • Published : 2011.06.30
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Abstract

Malignant Sertoli cell tumor was diagnosed in a 5-year-old male Shih Tzu dog. Clinical features of the dog were anorexia, urinary incontinence, constipation, anemia, alopecia, and epistaxis. The dog also had unilateral cryptorchid testis in the abdomen. Several abdominal and thoracic masses were identified on radiography. Grossly, the cryptorchid testicular mass was markedly enlarged to 8 cm in diameter. On cut surface, firm and well demarcated milk-white neoplastic areas were irregularly separated by white fibrous bands. Histologically, the testicular mass was diagnosed as tubular pattern Sertoli cell tumor. In addition, abdominal and mediastinal lymph nodes metastasis were found. Immunohistochemically, the tumor cells were strongly positive for vimentin and neuron specific enolase, but negative for S-100 and cytokeratin.

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References

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