DOI QR코드

DOI QR Code

Eosinophilic granulomas in two dogs

  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jung, Ji-Youl (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Kang, Sang-Chul (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Lee, Young-Rak (Gangnam Animal Medical Center) ;
  • Lee, Jin-Yong (Cats and Dogs Animal Clinic) ;
  • Hwang, Eui-Kyung (College of Life Science and Natural Resources, Sangji University) ;
  • Woo, Gye-Hyeong (Department of Clinical Laboratory Science, Semyung University) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • Accepted : 2010.11.11
  • Published : 2011.03.30

Abstract

Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare in dogs and horses. The skin biopsies of 5 years old female Cocker spaniel and 2 years old female mixed dog had the clinical signs of skin nodules with alopecia were submitted for diagnosis. Solitary skin nodules and papillary nodules were presented on the left external ear and back of Cocker spaniel and on the external ear of mixed dog, respectively. Histopathologically, epidermis of skin showed mild to severe hyperplasia with multifocal ulceration. Small to large irregular, brightly eosinophilic foci with degenerating eosinophils and homogeneous degenerated collagens were existed in the dermis of both ear and back skin. Typical 'flame figures', a mixture of degenerated collagen and degranulated eosinophils, were observed in both cases. Based on the histopathologic findings and special staining characters, 2 cases were diagnosed as canine eosinophilic granuloma. This is the first report for the eosinophilic granuloma of dogs in Korea.

Keywords

References

  1. 전형규, 박세진, 김덕환, 김문호, 서금원, 서청령, 요진재, 궐호현, 정한문. 후지 마비견에 대한 봉독 약침 및 봉독 약침과 한약제 병용치료. 한국임상수의학회지 2007, 24, 225-228.
  2. 전형규, 오현욱, 김현화, 한지원, 박진호, 이영원, 정성목, 김덕환. 척수 연화증 개에서 전통수의학적 방법을 이용한 치료 시도. 한국임상수의학회지 2007, 24, 608-612.
  3. 임지혜, 정창수, 변예은, 김완희, 이영원, 권오경. 소형견에서 섬유연골 색전성 척수증 2례. 한국임상수의학회지 2006, 23, 218-221.
  4. Cauzinille L. Fibrocartilaginous embolism in dogs. Vet Clin North Am Small Anim Pract 2000, 30, 155-167.
  5. Cauzinille L, Kornegay JN. Fibrocartilaginous embolism of the spinal cord in dogs: review of 36 histologically confirmed cases and retrospective study of 26 suspected cases. J Vet Intern Med 1996, 10, 241-245. https://doi.org/10.1111/j.1939-1676.1996.tb02056.x
  6. Doige CE, Parent JM. Fibrocartilaginous embolism and ischemic myelopathy in a four month old German shepherd dog. Can J Comp Med 1983, 47, 499-500.
  7. Etienne C. Clinical Veterinary Advisor: Dogs and Cats. 1st ed. pp. 388-400, Mosby, St. Louis, 2006.
  8. Evans DE, Kobrine AI, Rizzoli HV. Cardiac arrhythmias accompanying acute compression of the spinal cord. J Neurosurg 1980, 52, 52-59. https://doi.org/10.3171/jns.1980.52.1.0052
  9. Gandini G, Cizinauskas S, Lang J, Fatzer R, Jaggy A. Fibrocartilaginous embolism in 75 dogs: clinical findings and factors influencing the recovery rate. J Small Anim Pract 2003, 44, 76-80. https://doi.org/10.1111/j.1748-5827.2003.tb00124.x
  10. Gill CW. Fibrocartilaginous embolic myelopathy in a dog. Can Vet J 1979, 20, 273-278.
  11. Gondim FA, Lopes AC Jr, Oliveira GR, Rodrigues CL, Leal PR, Santos AA, Rola FH. Cardiovascular control after spinal cord injury. Curr Vasc Pharmacol 2004, 2, 71-79. https://doi.org/10.2174/1570161043476474
  12. Greenhoot JH, Shiel FO, Mauck HP Jr. Experimental spinal cord injury. Electrocardiographic abnormalities and fuchsinophilic myocardial degeneration. Arch Neurol 1972, 26, 524-529. https://doi.org/10.1001/archneur.1972.00490120064007
  13. Hawthorne JC, Wallace LJ, Fenner WR, Waters DJ. Fibrocartilaginous embolic myelopathy in miniature schnauzers. J Am Anim Hosp Assoc 2001, 37, 374-383.
  14. Jeong SM, Kim HY, Lee CH, Kweon OK, Nam TC. Use of acupuncture for the treatment of idiopathic facial nerve paralysis in a dog. Vet Rec 2001, 148, 632-633. https://doi.org/10.1136/vr.148.20.632
  15. Jeong SM, Park SW. Application of traditional acupuncture on canine intervertebral disc disease. J Vet Clin 2004, 21, 49-51.
  16. Jun HK, Oh HU, Lee HH, Han JW, Lee BK, Park JH, Lee YH, Jeong SM, Kim DH. Therapeutic approach by traditional veterinary medicine in a case with canine myleomalacia: Case report. J Vet Clin 2007, 24, 608-612.
  17. Kim DH, Liu J, Choi SH, MacManus P, Jennings P, Darcy K, Burke F, Leorald N, Rogers PAM. Acupuncture treatment in a case with equine laminitis. J Vet Clin 2006, 23, 6-8.
  18. Kim DH, Liu J, Lee YW, Song KH, Kang SK, Choi HJ, Seo KM, Choi SH, Nam TC, Rogers PAM. Treatment of canine cervical and lumbar disc disease by injection-acupuncture. J Vet Clin 2006, 23, 65-68.
  19. Kim DH, Liu J, MacManus P, Jennings P, Darcy K, Burke F, Slattery G, Rogers PAM. Injectionacupuncture with dexamethasone and modified moxibustion treatment of a downer cow. J Vet Clin 2006, 23, 69-71.
  20. Kim YS, Kim KW, Kim JY, Liu J, Lee SE, Song KH, Kim MC, Kim DH. The anti-emetic effect on needling acupuncture, aquapuncture and moxibustion at BL-21 and CV-12 in xylazine induced vomiting of dogs. J Vet Clin 2005, 22, 202-205.
  21. Lehmann KG, Lane JG, Piepmeier JM, Batsford WP. Cardiovascular abnormalities accompanying acute spinal cord injury in humans: incidence, time course and severity. J Am Coll Cardiol 1987, 10, 46-52. https://doi.org/10.1016/S0735-1097(87)80158-4
  22. Nakamoto Y, Ozawa T, Katakabe K, Nishiya K, Mashita T, Morita Y, Yasuda N, Ishii Y, Nakaichi M, Itamoto K. Usefulness of an early diagnosis for the favorable prognosis of fibrocartilaginous embolism diagnosed by magnetic resonance imaging in 10 smallto middle-sized dogs. Vet Res Commun 2008, 32, 609-617. https://doi.org/10.1007/s11259-008-9061-y
  23. Nakamoto Y, Ozawa T, Katakabe K, Nishiya K, Yasuda N, Mashita T, Morita Y, Nakaichi M. Fibrocartilaginous embolism of the spinal cord diagnosed by characteristic clinical findings and magnetic resonance imaging in 26 dogs. J Vet Med Sci 2009, 71, 171-176. https://doi.org/10.1292/jvms.71.171
  24. Ryu JH, Song KH, Kim DH, Kim MC, Shin ST, Cho SW. The therapeutic effect of aquapuncture on bovine foot rot. J Vet Clin 2002, 19, 115-120.
  25. Son SH, Kim YH, Kim NJ, Jun HK, Kim SH, Song KH, Lee YW, Kim DH. Modified moxibustion therapy for intervertebral disc disease in a dog. J Vet Sci (Chungnam National University) 2008, 15, 17-19.
  26. Teasell RW, Arnold JM, Krassioukov A, Delaney GA. Cardiovascular consequences of loss of supraspinal control of the sympathetic nervous system after spinal cord injury. Arch Phys Med Rehabil 2000, 81, 506-516. https://doi.org/10.1053/mr.2000.3848
  27. Ueno H, Shimizu J, Uzuka Y, Kobayashi Y, Hirokawa H, Ueno E, Suzuki A, Yamada K. Fibrocartilaginous embolism in a chondrodystrophoid breed dog. Aust Vet J 2005, 83, 142-144. https://doi.org/10.1111/j.1751-0813.2005.tb11620.x
  28. Xie H, Preast V. Xie's Veterinary Acupuncture. 1st ed. pp. 247-251, Wiley-Blackwell, Iowa, 2007.
  29. Young W, DeCrescito V, Tomasula JJ, Ho V. The role of the sympathetic nervous system in pressor responses induced by spinal injury. J Neurosurg 1980, 52, 473-481. https://doi.org/10.3171/jns.1980.52.4.0473