Journal of the Korean Crystal Growth and Crystal Technology (한국결정성장학회지)

The Korea Association of Crystal Growth (한국결정성장학회)
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Characterization of the biodegradable behavior for biphasic calcium phosphates using X-ray diffraction and lattice parameter

X-선 회절 및 격자 매개변수를 이용한 biphasic calcium phosphate 분말의 생분 해성 특성평가

  • Kim, Dong-Hyun (School of Materials Science Engineering, Pusan National University) ;
  • Song, Chang-Weon (School of Materials Science Engineering, Pusan National University) ;
  • Kim, Tae-Wan (School of Materials Science Engineering, Pusan National University) ;
  • Jin, Heoyng-Ho (School of Materials Science Engineering, Pusan National University) ;
  • Park, Hong-Chae (School of Materials Science Engineering, Pusan National University) ;
  • Yoon, Seog-Young (School of Materials Science Engineering, Pusan National University)
  • Received : 2011.06.14
  • Accepted : 2011.07.15
  • Published : 2011.08.31
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Abstract

Nanoscale-biodegradable behaviors of synthesized biphasic calcium phosphates (BCP) powders were characterized using X-ray diffraction (XRD), lattice parameter, and field emission microscopy (FE-SEM). The calcined BCP powders in vitro tested in Hank's balanced salt solution (pH = 7.4, $36.5^{\circ}C$) for 3 weeks. The calculated unit cell parameters for BCP have shown lattice distortion and expansion as irregular changes in the a and c-axis after in vitro.

합성된 biphasic calcium phosphate(BCP) 분말의 나노크기 생분해성 거동은 X-선 회절 분석방법, 격자 매개변수 및 전계방출형 주사전자현미경을 통해 특성평가 하였다. BCP 분발은 공침반응 및 하소과정을 통해 합성하였고, 합성된 분발은 행크 용액 (pH = 7.4, $36.5^{\circ}C$)을 이용하여 3주 동안 in vitro 시험 하였다 분해 시험(in vitro) 후, BCP 단위포의 매개변수는 a 및 c축의 불규칙한 변화와 비슷한 격자 왜곡 및 팽창 거동을 보였다.

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References

  1. K.-B. Park, J.-W. Park, H.-U. Ahn, D.-J. Yang, S.-K. Choi, I.-S. Jang, S.-I. Yeo and J.-Y. Suh, "Comparative study on the physicochemical properties and cytocom patibility of microporous biphasic calcium phosphate ceramics as a bone graft substitute", Journal of Periodontal & Implant Science 36 (2006) 797.
  2. R.W. Bucholz, A. Carlton and R.E. Holmes, "Hydroxyapatite and tricalcium phosphate bone graft substitutes", Orthop. Clic. North Am. 18 (1987) 323.
  3. W. Suchanek and M. Yoshimura, "Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants", J. Mater. Res. 13 (1998) 94. https://doi.org/10.1557/JMR.1998.0015
  4. Y. Ota, T. Iwashita, T. Kasuga, Y. Abe and A. Seki, "Bone formation following implantation of fibrous compounds ($\beta$-$Ca(PO_{3})_{2}$, $CaCO_{3}$(aragonite)) into bone marrow", J. Mater. Sci. 12 (2002) 895.
  5. J.H. Kim, Y.M. Park, T.Y. Yang, S.Y. Yoon and H.C. Park, "Microstructural develpment in synthetic hydroxyapatite", J. Kor. Ceram. Soc. 41 (2004) 289. https://doi.org/10.4191/KCERS.2004.41.4.289
  6. D.J. Baek, T.Y. Yang, Y.B. Lee, S.Y. Yoon and H.C. Park, "Fabrication of hydroxyapatite whiskers by hydrolysis of $\alpha$-TCP", J. Kor. Ceram. Soc. 40 (2003) 608. https://doi.org/10.4191/KCERS.2003.40.6.608
  7. S.H. Kwon, Y.K. Jun, S.H. Hong and H.E. Kim, "Synthesis and dissolution behavior of $\beta$-TCP and HA/$\beta$- TCP composite powders", J. Eur. Ceram. Soc. 23 (2003) 1039. https://doi.org/10.1016/S0955-2219(02)00263-7
  8. R. Xin, Y. Leng, J. Chen and Q. Zhang, "A comparative study of calcium phosphate formation on bioceramics in vitro and in vivo", Biomaterials 26 (2005) 6477. https://doi.org/10.1016/j.biomaterials.2005.04.028
  9. S.-H. Kwon, Y.-K. Jun, S.-H. Hong and H.-E. Kim, "Synthesis and dissolution behavior of $\beta$-TCP and HA/ $\beta$-TCP composite powders", J. Euro. Ceram. Soc. 23 (2003) 1039. https://doi.org/10.1016/S0955-2219(02)00263-7