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New bone formation using fibrin rich block with concentrated growth factors in maxillary sinus augmentation

성장 인자가 농축된 Fibrin rich block을 이용한 상악동 거상술에서의 신생골 형성에 관한 연구

  • Kim, Ji-Min (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Daegu Catholic University Medical Center) ;
  • Lee, Ju-Hyoung (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Daegu Catholic University Medical Center) ;
  • Park, In-Sook (Division of Oral and Maxillofacial Surgery, Department of Dentistry, Daegu Catholic University Medical Center)
  • 김지민 (대구가톨릭대학병원 치과 구강악안면외과) ;
  • 이주형 (대구가톨릭대학병원 치과 구강악안면외과) ;
  • 박인숙 (대구가톨릭대학병원 치과 구강악안면외과)
  • Received : 2011.03.29
  • Accepted : 2011.07.25
  • Published : 2011.08.31

Abstract

Introduction: This study examined the predictability of new bone formation in the pneumatized maxillary sinus using only fibrin-rich blocks with concentrated growth factors as an alternative to bone grafts. Materials and Methods: Maxillary sinus augmentation was performed in thirty-three patients with a deficient alveolar bone height (mean 3.9 mm). All patients were treated consecutively with sinus membrane elevation via the lateral window approach and panoramic radiograms and cone-beam computed tomograms were taken to evaluate the remaining bone height and the new bone formation in the maxillary sinus, before and after surgery. Four biopsy specimens were taken at the time of implant consolidation (after an average of five months healing) and were stained by H & E and Trichrome staining. Results: None of the patients had postoperative complications during implant consolidation. After an average of 5 months since sinus augmentation, newly formed bone was observed in all cases by a radiographic evaluation. In 4 biopsy samples, newly formed bone was observed along the floor of the replaced bony window. The osteoblast lining and well distinguished Osteocytes in the lacunas were observed in the newly formed bone. Of the 74 implants (4 different surfaced implants - resorbable blast media-surfaced (RBM), Hydroxyapatite (HA) coated, acid-etched, sintered porous-surfaced implant) placed, one RBM implant failed. The success rate was 98.6% after a mean of 15 months. Discussion: These results suggest that maxillary sinus augmentation using fibrin rich block with concentrated growth factors is a successful and predictable technique.

Keywords

References

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