DOI QR코드

DOI QR Code

Monitoring of Heavy Metal Contents in Commercial Herbal Medicines

유통 한약재의 중금속 잔류실태 조사

  • Jang, Seol (Herbal Material Management Team, Korea Institute of Oriental Medicine) ;
  • Kim, Tae Hee (Herbal Material Management Team, Korea Institute of Oriental Medicine) ;
  • Lee, Ah Reum (Herbal Material Management Team, Korea Institute of Oriental Medicine) ;
  • Lee, A Yeong (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine) ;
  • Choi, Goya (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine) ;
  • Kim, Ho Kyoung (Herbal Material Management Team, Korea Institute of Oriental Medicine)
  • 장설 (한국한의학연구원 한약소재관리팀) ;
  • 김태희 (한국한의학연구원 한약소재관리팀) ;
  • 이아름 (한국한의학연구원 한약소재관리팀) ;
  • 이아영 (한국한의학연구원 한약기초연구그룹) ;
  • 최고야 (한국한의학연구원 한약기초연구그룹) ;
  • 김호경 (한국한의학연구원 한약소재관리팀)
  • Received : 2012.09.24
  • Accepted : 2012.11.09
  • Published : 2012.12.30

Abstract

This study was conducted to determine the contents of heavy metal in commercial herbal medicines. The monitoring of lead, arsenic, cadmium and mercury was carried out on 100 samples with 10 kinds of herbal medicines. The contents of heavy metal were measured by inductively coupled plasma atomic emission spectrometry (ICP-AES) and mercury analyzer. The mean values of heavy metal contents for herbal medicines were Pb 1.87 mg/kg, As 0.39 mg/kg, Cd 0.26 mg/kg and Hg 0.021 mg/kg. Of the total samples, 19 samples (19%, 4 types) were violated the KFDA regulatory guidance of heavy metal in herbal medicines (9 samples on Pb, 10 samples on Cd). Among these 19 unsuitable samples, 16 samples were domestic and 3 samples were imported. Therefore, we need continuously monitoring to ensure confidence and safety for these herbal medicines.

Keywords

References

  1. Jung SJ, Kang ST, Han CH, Kim SJ, Ko SK, Kim YH, Kim YK, Kim BS and Choi BH. (2010). Survey of heavy metal contents and intake rates after decoction in herbal medicines classified by parts. Journal of Food Hygiene and Safety. 25:402-409.
  2. Jung SJ, Lee SD, Kim SJ, Jo SA, Kim NH, Jung HJ, Kim HS and Han KY. (2011). Monitoring of sulfur dioxide residue in commercial medicinal herbs in Seoul (2010). Journal of Food Hygiene and Safety. 26:435-447.
  3. Kim DK, Kim BS, Han EJ, Han CH, Kim OH, Choi BH, Hwang IS, Chae YZ, Kim MY and Park SK. (2009). Distribution of hazardous heavy metals in commercial herbal medicines classified by plant parts used in Seoul. Analytical Science & Technology. 22:504-513.
  4. Kim MK, Hur MH, Lee CH, Jin JS, Jin SK and Lee YJ. (2004). Monitoring of residual sulfur dioxide in herbal medicines. Korean Journal of Pharmacognosy. 35:276-282.
  5. Kim SJ. (2001). A study on the consumption pattern and pricing structure of major oriental medicine in Korea. A MOHW Research Paper. p.77-78.
  6. Korea Food & Drug Administration. (2005). KFDA Notification No. 2005-2062. p.1-2.
  7. Korea Food & Drug Administration. (2011). KFDA Notification No. 2011-2042. p.3-5.
  8. Lee HH, Seo JM, Oh MS, Gang IS, Park JJ, Seo KW, Ha DR and Kim ES. (2010). A survey on harmful materials of commercial medical herb in Gwangju area. Journal of Food Hygiene and Safety. 25:83-90.
  9. Lee JT. (2006). Research on intake of chinese medicine by Korea. A KFDA Research Paper. p.16-22.
  10. Lee MK, Park JS, Lim HC and Na HS. (2008). Determination of heavy metal contents in medicinal herb. Korean Journal of Food Preservation. 15:253-260.
  11. Lee SE, Lee JH, Kim JK, Kim GS, Kim YO, Seo JS, Choi JH, Lee ES, Noh HJ and Kim SY. (2011). Anti-inflammatory activity of medicinal plant extracts. Korean Journal of Medicinal Crop Science. 19:217-226. https://doi.org/10.7783/KJMCS.2011.19.4.217
  12. Massaro EJ. (1990). Handbook of human toxicology. Boca Raton Press. New York. New York, USA. p.149-188.
  13. Park MK, Kim SY and Hwang HU. (2004). A study on the heavy metal contents in herbal medicines -Cultivated herbal medicines at north Gyeongbuk area-. Journal of the Environmental Sciences. 13:1117-1122. https://doi.org/10.5322/JES.2004.13.12.1117
  14. Reilly C. (1980). Metal contamination of food. Applied Science Publisher Ltd. London, England. p.119-122.
  15. Reilly C. (1991). Metal contamination of food. 2nd edition. Elsevier Science Publisher Ltd. London, England. p.95-98.
  16. The Ministry of Health and Welfare. (1995). MOHW Notification No. 1995-1944. p.326.
  17. World Health Organization. (1997). Lead (Environmental Health Criteria 3). WHO. p.44-54.
  18. Yim OK, Han EJ, Chung JY, Park KS, Kang IH, Kang SJ and Kim YJ. (2009). The monitoring of some heavy metals in oriental herbal medicines and their intake rates. Analytical Science & Technology. 22:128-135.
  19. Yoon YT, Lee SD, Park AS, Shin Y, Kim HS, Kim YK and Choi BH. (2010). Analysis of sulfur dioxide residue in commercial medicinal herbs in Seoul(2009). Korean Journal of Medicinal Crop Science. 18:345-360.

Cited by

  1. Monitoring of Residual Sulfur Dioxide in Herbal Medicines Distributed at Domestic vol.21, pp.2, 2013, https://doi.org/10.7783/KJMCS.2013.21.2.124
  2. Characteristics of Growth and Yield by Planting Density and Mulching Materials in Salvia miltiorrhiza Bunge vol.21, pp.3, 2013, https://doi.org/10.7783/KJMCS.2013.21.3.179
  3. A Survey on the Management Status of Extramural Herbal Dispensaries vol.24, pp.1, 2016, https://doi.org/10.14374/HFS.2016.24.1.1
  4. Monitoring of Cd, Hg, Pb, and As and Risk Assessment for Commercial Medicinal Plants vol.34, pp.4, 2015, https://doi.org/10.5338/KJEA.2015.34.4.43
  5. Sulfur Dioxide, Heavy Metal and Curcumin Contents in Market-Available Turmeric (Curcuma longa L.) vol.24, pp.2, 2016, https://doi.org/10.7783/KJMCS.2016.24.2.121
  6. Synergistic Effect of Brazilein in Combination with Hygromycin-b against Staphylococcus aureus vol.22, pp.6, 2014, https://doi.org/10.7783/KJMCS.2014.22.6.504
  7. Changes of Major Components and Growth Characteristics According to Harvesting Times of Salvia miltiorrhiza Bunge vol.23, pp.5, 2015, https://doi.org/10.7783/KJMCS.2015.23.5.395