Journal of Society of Preventive Korean Medicine (대한예방한의학회지)

Society of Preventive Korean Medicine (대한예방한의학회)
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As, Cd, Pb, Co, Cr Concentration and Property Evaluation in Frequently Using 16 Oriental Herbal Medicines -Mainly Average, Lowest, Highest Concentration and Percent Exceeding Value of Legal Allowance in Korean and Chinese Origines-

16종 다용한약재의 산지별 As, Cd, Pb, Co, Cr 농도 및 특성고찰 -한국과 중국산의 평균농도, 최소-최대농도와 법적 허용농도초과비율을 중심으로-

  • Kim, Kee-Dong (Dept. of Fine Analysis and Advanced Materials, College of Science and Engineering, Sangji University) ;
  • Park, Hae-Mo (Dept. of Preventive Medicine, College of Oriental Medicine, Sangji University) ;
  • Seo, Yong-Chan (Dept. of Environmental Engineering, College of Science and Engineering, Sangji University) ;
  • Lee, Sun-Dong (Dept. of Preventive Medicine, College of Oriental Medicine, Sangji University)
  • 김기동 (상지대학교 정밀화학신소재학과) ;
  • 박해모 (상지대학교 한의과대학 예방의학교실) ;
  • 서용찬 (상지대학교 환경공학과) ;
  • 이선동 (상지대학교 한의과대학 예방의학교실)
  • Received : 2012.12.06
  • Accepted : 2012.12.29
  • Published : 2012.12.31
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Abstract

Objective : Average, lowest, highest concentration and exceeding value of legal allowance of As, Cd, Pb, Co, Cr in frequently using 16 oriental herbal medicines in korea(Astragali Radix, Ginseng, Citri Unshii Pericarpium, Aurantii Fructus Immaturus, Angelicae Gigantis Radix, Cnidii Rhizoma, Paeoniae Radix, Rehmanniae Radix Preparata, Zingiberis Rhizoma Crudus, Zizyphi Fructus, Atractylodis Rhizoma Alba, Hoelen, Dioscoreae Rhizoma, Corni Fructus, Schisandrae Fructus, Lycii Fructus) was evaluated according to their origines (korea, china) and property was also discussed according to the medicinally active part and individuals regardless origines. Method : Korean and Chinese herbal medicines were evenly sampled from corresponding country nationwide. Pre-treatment was executed according to the KFDA(Korea Food and Drug Administration) regulation and analysis was performed according to the Korean Environmental Analysis QA/QC. Result : Not much difference was observed according to their origines. However, lowest, highest and percent exceeding value of legal allowance was showed some consistent differences according to the medicinally active part and individuals. Co and Cr was can not be evaluated since their legal regulation was not established yet. Conclusion : The average concentration of As, Cd, Pb, Co, Cr in frequently using 16 oriental herbal medicines in korea showed no noticeable difference according to their origines. Regardless the origin, some consistent differences were observed according to the individuals and medicinally active parts.

Keywords

References

  1. Sun-Dong Lee, Jeong-Suk Lee, Myung- Dong Kim. Urine and Hair Metal Correlation in Subjects with Long Term Intake of Herbal Medicine. Journal of Oriental Preventive Medical Society. 2002 ; 6(1) : 129-139
  2. Sun-Dong Lee, Jin-Yong Jung, Kyung-Ho Choi, Jong-Tae Lee, Hae-Mo Park, Heon- Tae Shin. Risk Analysis and Estimating Consumption of Heavy Metal from Intake of Oriental Medicines. J. Env. Hlth. Sci. 2010 ; 36(1) : 14-19
  3. Jung-Yeol Lee, Sun-Dong Lee. Comparison of Blood Metal Concentration in Ohjeoksan Treated Rats - Dose-Response Relationship and Mechanism. J Korean Oriental Med. 2002 ; 23(1) : 67-82
  4. Massaro, E.J. Handbook of Human Toxicology. Boca Raton Press, New York. 1990. p149-188
  5. 보건복지부 고시 1996-26호, 한약재 품질 및 유통관리. 1996.
  6. 식품의약품안전청. 생약 등의 잔류.오염물질 기준 및 시험방법 개정고시 제2011-42호(2011. 08. 22, 개정)
  7. Joint FAO/WHO Expert Committee on Food Additives(JECFA) : Safety Evaluation of Certain Food Additives and Contaminants. WHO Food Additives Series 44. International Programme on Chemical Safety and WHO, GENEVA. 2000. p273-39
  8. Suk-Kyung Ko, Hyun-Jeung Seung, Young- Me Song, In-sil Yu, Sung-Min Choi, Hee-Gon Kang. Contents of Heavy Metals of Commercial Herbal Medicines in Seoul Area. Report of Seoul Institute of Health & Environment. 2003 ; 39 : 31-43
  9. Young Shin, Jae-Eun Kwak, Chang-Ho Han, Young-Sook Hwang, Ae-Sook Park, Dong-Gyu Kim, Eun-Jung Han, Sam-Ju Jung, Bog-Soon Kim, Byung-Hyun Choi. Monitoring of Heavy Metal in Herbal Medicines from Markets in Seoul by ICPMS. Report of Seoul Institute of Health & Environment. 2007 ; 43 : 226-246
  10. Eun-Jung Han, Dong-Gyu Kim, Chang-Ho Han, Ouk-Hee Kim, Jae-Eun Kwak, Sam- Ju Jung, Bog-soon Kim, Byung-Hyun Jung. Heavy Metal Contents of Herbal Medicines in Common Use for Food and Medicine from Markets in Seoul. Report of Seoul Institute of Health & Environment. 2008 ; 44 : 126-139
  11. 한국보건사회연구원. 한방 의료이용 및 한약 소비 실태조사. 보건복지부. 2011. p328-348
  12. 환경부. 환경시험.검사 QA/QC 핸드북. 국립환경과학원. 2011.
  13. Sam-Ju Jung, Sung-Tae Kang, Chang-Ho Han, Su-Jin Kim, Suk-Kyung Ko, Yun- Hee Kim, Yoo-Kyung Kim, Bog-Soon Kim, Byung-Hyun Choi. Survey of Heavy Metal Contents and Intake Rates after Decoction in Herbal Medicines Classified by Parts. J. Fd Hyg. Safety. 2010 ; 25(4) : 402-409
  14. Moon-Ki Park, Hyeun-Jeung Lee, Kwang- Joong Kim, Young-Soo Moon. The Correlation of Heavy Metal Contents in Herbal Medicines and Their Soils at North Gyeongbuk Area. Journal of the Environmental Sciences. 2005 ; 14(2) : 185-192. https://doi.org/10.5322/JES.2005.14.2.185
  15. Sang-Baek Han. Heavy Metal Concentrations of Herbal Medicines Produced in Korea, China and Other Countries. Thesis of Master degree in Oriental Medicine. Sangji University. 1998
  16. Il-Hyung Jeong, Jong-Hwa Kim, Jong- Sup Jeon, Sang-Hun Cho, Shin-Hee Park, Hyun-Ye Jo, Young-Sug Kim. Safety Assessment of Oriental Medicines and Their Preparations. J. Fd Hyg. Safety. 2010 ; 25 (3) : 232-237
  17. Hyang-Hee Lee, Jung-Mi Seo, Mu-Sul Oh, In-Sook Gang, Jong-Jin Park, Kye-Won Seo, Dong-Ryong Ha, Eun-Sun Kim. A Survey on Harmful Materials of Commercial Medical Herb in Gwangju Area. J. Fd Hyg. Safety. 2010 ; 25(2) : 83-90
  18. Mi-Kyung Lee, Jung-Suk Park, Hyun- Cheol Lim, Hwan-Sik Na. Determination of Heavy Metal Contents in Medicinal Herb. Korean J. Food Presserv. 2008 ; 15(2) : 253-260
  19. 중약대사전 편찬위원회. 중약대사전 1권. 도서출판 정담. 2004. p888, 1707
  20. Kim Kwnag Joong, Yang Chae Ha, Kwon Yong Kyu, Lee Hyeun Jeung. Studies on the Heavy Metal Contents in Cultivated Herbal Medicines and Their Soils at North Kyungbuk Area. Korean J. Oriental Physiology & Pathology. 2003 ; 17(3) : 1419-1426