Korean Journal of Plant Resources (한국자원식물학회지)

The Plant Resources Society of Korea (한국자원식물학회)
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Effects of Korean Ginseng and Wild Simulated Cultivation Ginseng for Muscle Strength and Endurance

  • Sohn, Eun-Hwa (Department of Herbal Medicine Resource, Kangwon National University) ;
  • Yang, Yoon Jung (Department of Life Science, Gachon University) ;
  • Koo, Hyun Jung (Department of Life Science, Gachon University) ;
  • Park, Dae Won (Department of Life Science, Gachon University) ;
  • Kim, Ye-Jin (Department of Herbal Medicine Resource, Kangwon National University) ;
  • Jang, Ki Ho (Department of Food and Nutrition, Kangwon National University) ;
  • NamKoong, Seung (Department of Physical Therapy, Kangwon National University) ;
  • Kang, Se Chan (Department of Life Science, Gachon University)
  • Received : 2012.10.15
  • Accepted : 2012.12.03
  • Published : 2012.12.31
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Abstract

Muscle strength and endurance activities of Korean ginseng (Panax ginseng C. A. Meyer; KG) were compared with those of wild simulated cultivation ginseng (WCG) in mice. Fifty male ICR mice were divided into five groups: A (vehicle); B (WCG 100 mg/kg); C (WCG 500 mg/kg); D (KG 100 mg/kg); E (KG 500 mg/kg). Subsequently, the mice were subjected to the forced swimming test (FST) and treadmill test at the $4^{th}$ and $7^{th}$ weeks. The glycogen content in the muscle and blood analysis (levels of glucose, triglyceride (TG), IGF-1) were also performed immediately after the last FST and treadmill test at the $7^{th}$ week. Immobility times in FST were shorter in WCG- than KG-treated groups, and the results of the treadmill tests were also significant except for KG-treated at 100 mg/kg. The glycogen content was increased in both groups with a peak at 500 mg/kg of WCG groups. Serum concentrations of TG and glucose were decreased by administration of KG and WCG and all treated groups showed increase in the level of IGF-1 in serum. These results suggest that KG and WCG supplementations are effective in escalating the muscle strength and endurance.

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References

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