Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
권호 표지
DOI QR코드

DOI QR Code

An Indigenous Case of Intestinal Capillariasis with Protein-Losing Enteropathy in Korea

  • Jung, Woon Tae (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Kim, Hyun Jin (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Min, Hyun Ju (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Ha, Chang Yoon (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Kim, Hong Jun (Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Ko, Gyung Hyuck (Department of Pathology, Gyeongsang National University School of Medicine) ;
  • Na, Byoung-Kuk (Department of Parasitology and Institute of Health Sciences, Gyeongsang National University School of Medicine) ;
  • Sohn, Woon-Mok (Department of Parasitology and Institute of Health Sciences, Gyeongsang National University School of Medicine)
  • Received : 2012.06.20
  • Accepted : 2012.07.09
  • Published : 2012.12.17
Download PDF
⟨ Previous Next ⟩

Abstract

We encountered an indigenous case of intestinal capillariasis with protein-losing enteropathy in the Republic of Korea. A 37-year-old man, residing in Sacheon-si, Gyeongsangnam-do, admitted to the Gyeongsang National University Hospital (GNUH) due to long-lasting diarrhea, abdominal pain, anasarca, and weight loss. He recalled that he frequently ate raw fish, especially the common blackish goby (Acanthogobius flavimanus) and has never been abroad. Under the suspicion of protein-losing enteropathy, he received various kinds of medical examinations, and was diagnosed as intestinal capillariasis based on characteristic sectional findings of nematode worms in the biopsied small intestine. Adults, juvenile worms, and eggs were also detected in the diarrheic stools collected before and after medication. The clinical symptoms became much better after treatment with albendazole 400 mg daily for 3 days, and all findings were in normal range in laboratory examinations performed after 1 month. The present study is the 6th Korean case of intestinal capillariasis and the 3rd indigenous one in the Republic of Korea.

Keywords

References

  1. Chitwood MB, Valesquez C, Salazar NG. Capillaria philippinensis sp. n. (Nematoda: Trichinellidae), from the intestine of man in the Philippines. J Parasitol 1968; 54: 368-371. https://doi.org/10.2307/3276953
  2. Whalen GE, Rosenberg EB, Strickland GT, Gutman RA, Cross JH, Watten RH. Intestinal capillariasis. A new disease in man. Lancet 1969; 1: 13-16.
  3. Pradatsundarasar A, Pecharanónd K, Chintanawóngs C, Ungthavórn P. The first case of intestinal capillariasis in Thailand. Southeast Asian J Trop Med Public Health 1973; 4: 131-134.
  4. Mukai T, Shimizu S, Yamamoto M, Horiuchi I, Kishimoto S, Kajiyama G. A case of intestinal capillariasis. Jpn Arch Intern Med 1983; 30: 163-169.
  5. Hoghooghi-Rad N, Maraghi S, Narenj-Zadeh A. Capillaria philippinensis infection in Khoozestan Province, Iran: Case report. Am J Trop Med Hyg 1987; 37: 135-137. https://doi.org/10.4269/ajtmh.1987.37.135
  6. Chen CY, Hsieh WC, Lin JT, Liu MC. Intestinal capillariasis: Report of a case. Taiwan Yi Xue Hui Za Zhi 1989; 88: 617-620.
  7. Youssef FG, Mikhail EM, Mansour NS. Intestinal capillariasis in Egypt: A case report. Am J Trop Med Hyg 1989; 40: 195-196. https://doi.org/10.4269/ajtmh.1989.40.195
  8. Chichino G, Bernuzzi AM, Bruno A, Cevini C, Atzori C, Malfitano A, Scaglia M. Intestinal capillariasis (Capillaria philippinensis) acquired in Indonesia: A case report. Am J Trop Med Hyg 1992; 47: 10-12. https://doi.org/10.4269/ajtmh.1992.47.10
  9. el Hassan EH, Mikhail WE. Malabsorption due to Capillaria philippinensis in an Egyptian woman living in Dubai, United Arab Emirates. Trans R Soc Trop Med Hyg 1992; 86:79. https://doi.org/10.1016/0035-9203(92)90450-Q
  10. Lee SH, Hong ST, Chai JY, Kim WH, Kim YT, Song IS, Kim SW, Choi BI, Cross JH. A case of intestinal capillariasis in the Republic of Korea. Am J Trop Med Hyg 1993; 48: 542-546. https://doi.org/10.4269/ajtmh.1993.48.542
  11. Kang G, Mathan M, Ramakrishna BS, Mathai E, Sarada V. Human intestinal capillariasis: first report from India. Trans R Soc Trop Med Hyg 1994; 88:
  12. Soukhathammavong P, Sayasone S, Harimanana AN, Akkhavong A, Thammasack S, Phoumindr N, Choumlivong K, Choumlivong K, Keoluangkhot V, Phongmany S, Akkhavong K, Hatz C, Strobel M, Odermatt P. Three cases of intestinal capillariasis in Lao People's Democratic Republic. Am J Trop Med Hyg 2008; 79: 735-738.
  13. Dronda F, Chaves F, Sanz A, Lopez-Velez R. Human intestinal capillariasis in an area of nonendemicity: Case report and review. Clin Infect Dis 1993; 17: 909-912. https://doi.org/10.1093/clinids/17.5.909
  14. Hong ST, Kim YT, Choe G, MinYI, Cho SH, Kim JK, Kook J, Chai JY, Lee SH. Two cases of intestinal capillariasis in Korea. Korean J Parasitol 1994; 32: 43-48. https://doi.org/10.3347/kjp.1994.32.1.43
  15. Lee SH, Rhee PL, Lee JH, Lee KT, Le JK, Sim SG, Lee SK, Kim JJ, Ko KC, Paik SW, Rhee JC, Choi KW, Lee NY, Cho SL, Ryu KH. A case of intestinal capillariasis: fourth case report in Korea. Korean J Gastroenterol 1999; 34: 542-546 (in Korean). https://doi.org/10.1007/s005350050312
  16. Kwon Y, Jung HY, Ha HK, Lee I. An imported case of intestinal capillariasis presenting as protein-losing enteropathy. Korean J Pathol 2000; 34: 235-238 (in Korean).
  17. Vasantha PL, Girish N, Leela KS. Human intestinal capillariasis: A rare case report from non-endemic area (Andhra Pradesh, India). Indian J Med Microbiol 2012; 30: 236-239. https://doi.org/10.4103/0255-0857.96708
  18. Attia RA, Tolba ME, Yones DA, Bakir HY, Eldeek HE, Kamel S. Capillaria philippinensis in Upper Egypt: has it become endemic? Am J Trop Med Hyg 2012; 86: 126-133. https://doi.org/10.4269/ajtmh.2012.11-0321
  19. Saichua P, Nithikathkul C, Kaewpitoon N. Human intestinal capillariasis in Thailand. World J Gastroenterol 2008; 14: 506-510. https://doi.org/10.3748/wjg.14.506
  20. Lu LH, Lin MR, Choi WM, Hwang KP, Hsu YH, Bair MJ, Liu JD, Wang TE, Liu TP, Chung WC. Human intestinal capillariasis (Capillaria philippinensis) in Taiwan. Am J Trop Med Hyg 2006; 74: 810-813.
  21. Belizario VY, de Leon WU, Esparar DG, Galang JM, Fantone J, Verdadero C. Compostela Valley: A new endemic focus for capillariasis philippinensis. Southeast Asian J Trop Med Public Health 2000; 31: 478-481.
  22. Cross JH. Capillaria philippinensis and Trichostrongylus orientalis. In: Farthing MJG, Keusch GT, Wakelin D, eds, Enteric infection 2. Intestinal helminthes. London, UK. Chapman & Hall Medical. 1995, p 151-164.

Cited by

  1. Intestinal Capillariasis Diagnosed by Endoscopic Biopsy vol.46, pp.6, 2012, https://doi.org/10.5946/ce.2013.46.6.675
  2. Intestinal capillariasis in the 21 st century: clinical presentations and role of endoscopy and imaging vol.14, pp.None, 2012, https://doi.org/10.1186/s12876-014-0207-9
  3. An Overview of Fish-borne Nematodiases among Returned Travelers for Recent 25 Years- Unexpected Diseases Sometimes Far Away from the Origin vol.56, pp.3, 2018, https://doi.org/10.3347/kjp.2018.56.3.215