Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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Carnoy's Solution Application for Patient Preliminarily Diagnosed with Keratocystic Odotogenic Tumor: Case Report

각화낭성치성종양으로 의심되는 환자의 Carnoy's Solution 적용: 증례보고

  • Choi, Seok-Tai (Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University, Brain Korea 21 Project) ;
  • Kim, Tae-Kwang (Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University, Brain Korea 21 Project) ;
  • Leem, Dae-Ho (Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University, Brain Korea 21 Project) ;
  • Baek, Jin-A (Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University, Brain Korea 21 Project) ;
  • Shin, Hyo-Keun (Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University, Brain Korea 21 Project) ;
  • Ko, Seung-O (Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University, Brain Korea 21 Project)
  • 최석태 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 김태광 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 임대호 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 백진아 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 신효근 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업) ;
  • 고승오 (전북대학교 치의학전문대학원 구강악안면외과학교실, 구강생체과학연구소, BK21사업)
  • Received : 2012.10.17
  • Accepted : 2012.11.23
  • Published : 2012.11.30
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Abstract

The odontogenic keratocyst (OKC) was originally classified as a developmental cyst, and OKC is histologically divided into orthokeratic and parakeratic types. According to revised histopathological classification of odontogenic tumors by the World Health Organization (2005), the term, keratocystic odontogenic tumor (KCOT) has been adopted to describe parakeratic OKC. The KCOT is noted for its capacity to recur after treatment. The aggressive, or potentially aggressive, nature of KCOT has led to alternative treatments. Among the treatments is noted the use of Carnoy's solution as adjunctive intralesional therapy having a low rate of recurrence. This study suggests a possible benefit of Carnoy's solution against recurrence of KCOT.

Keywords

References

  1. Philipsen HP. Keratocysts in the jaw. Tandlaegeblader 1956;60:963-80.
  2. The International Agency for Research on Cancer, Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005.
  3. Ahlfors E, Larsson A, Sjogren S. The odontogenic keratocyst: a benign cystic tumor? J Oral Maxillofac Surg 1984; 42:10-9. https://doi.org/10.1016/0278-2391(84)90390-2
  4. Kakarantza-Angelopoulou E, Nicolatou O. Odontogenic keratocysts: clinicopathologic study of 87 cases. J Oral Maxillofac Surg 1990;48:593-9. https://doi.org/10.1016/S0278-2391(10)80472-0
  5. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behaviour. Oral Oncol 2002;38:219-26. https://doi.org/10.1016/S1368-8375(01)00065-3
  6. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies. Oral Oncol 2002;38:323-31. https://doi.org/10.1016/S1368-8375(01)00066-5
  7. Williams TP, Connor FA Jr. Surgical management of the odontogenic keratocyst: aggressive approach. J Oral Maxillofac Surg 1994;52:964-6. https://doi.org/10.1016/S0278-2391(10)80081-3
  8. Stoelinga PJ. Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg 2001;30:14-25. https://doi.org/10.1054/ijom.2000.0027
  9. Nakamura N, Mitsuyasu T, Mitsuyasu Y, Taketomi T, Higuchi Y, Ohishi M. Marsupialization for odontogenic keratocysts: long-term follow-up analysis of the effects and changes in growth characteristics. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:543-53. https://doi.org/10.1067/moe.2002.128022
  10. Schmidt BL, Pogrel MA. The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts. J Oral Maxillofac Surg 2001;59:720-5. https://doi.org/10.1053/joms.2001.24278
  11. Chirapathomsakul D, Sastravaha P, Jansisyanont P. A review of odontogenic keratocysts and the behavior of recurrences. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:5-9. https://doi.org/10.1016/j.tripleo.2005.03.023
  12. Giuliani M, Grossi GB, Lajolo C, Bisceglia M, Herb KE. Conservative management of a large odontogenic keratocyst: report of a case and review of the literature. J Oral Maxillofac Surg 2006;64:308-16. https://doi.org/10.1016/j.joms.2005.10.013
  13. Meara JG, Shah S, Li KK, Cunningham MJ. The odontogenic keratocyst: a 20-year clinicopathologic review. Laryngoscope 1998;108:280-3. https://doi.org/10.1097/00005537-199802000-00022
  14. Donoff RB, Guralnick WC, Clayman L. Keratocysts of the jaws. J Oral Surg 1972;30:880-4.
  15. Harris M. Odontogenic cyst growth and prostaglandin-induced bone resorption. Ann R Coll Surg Engl 1978;60:85-91.
  16. Magnusson BC. Odontogenic keratocysts: a clinical and histological study with special reference to enzyme histochemistry. J Oral Pathol 1978;7:8-18. https://doi.org/10.1111/j.1600-0714.1978.tb01880.x
  17. Attenborough NR. Recurrence of an odontogenic keratocyst in a bone graft: report of a case. Br J Oral Surg 1974;12:33-9. https://doi.org/10.1016/0007-117X(74)90058-4
  18. Rud J, Pindborg JJ. Odontogenic keratocysts: a follow-up study of 21 cases. J Oral Surg 1969;27:323-30.
  19. Bataineh AB, al Qudah M. Treatment of mandibular odontogenic keratocysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;86:42-7. https://doi.org/10.1016/S1079-2104(98)90148-2
  20. Emerson TG, Whitlock RI, Jones JH. Involvement of soft tissue by odontogenic keratocysts (primordial cysts). Br J Oral Surg 1972;9:181-5.
  21. Jackson IT, Potparic Z, Fasching M, Schievink WI, Tidstrom K, Hussain K. Penetration of the skull base by dissecting keratocyst. J Craniomaxillofac Surg 1993;21:319-25. https://doi.org/10.1016/S1010-5182(05)80490-1
  22. Chuong R, Donoff RB, Guralnick W. The odontogenic keratocyst. J Oral Maxillofac Surg 1982;40:797-802. https://doi.org/10.1016/0278-2391(82)90177-X
  23. Gonzalez-Alva P, Tanaka A, Oku Y, et al. Keratocystic odontogenic tumor: a retrospective study of 183 cases. J Oral Sci 2008;50:205-12. https://doi.org/10.2334/josnusd.50.205
  24. Ogden GR, Chisholm DM, Kiddie RA, Lane DP. p53 protein in odontogenic cysts: increased expression in some odontogenic keratocysts. J Clin Pathol 1992;45:1007-10. https://doi.org/10.1136/jcp.45.11.1007
  25. Anand VK, Arrowood JP Jr, Krolls SO. Malignant potential of the odontogenic keratocyst. Otolaryngol Head Neck Surg 1994;111:124-9.
  26. Tanimoto K, Fujita M, Wada T, Koseki T, Fujiwara M, Uemura S. Radiologic features of odontogenic keratocyst in the mandibular ramus: for the differential diagnosis from ameloblastoma. Dent Radiol 1982;21:237-45.
  27. Crowley TE, Kaugars GE, Gunsolley JC. Odontogenic keratocysts: a clinical and histologic comparison of the parakeratin and orthokeratin variants. J Oral Maxillofac Surg 1992;50:22-6. https://doi.org/10.1016/0278-2391(92)90187-5
  28. Browne RM. The odontogenic keratocyst. Histological features and their correlation with clinical behaviour. Br Dent J 1971;131:249-59. https://doi.org/10.1038/sj.bdj.4802732
  29. Zachariades N, Papanicolaou S, Triantafyllou D. Odontogenic keratocysts: review of the literature and report of sixteen cases. J Oral Maxillofac Surg 1985;43:177-82. https://doi.org/10.1016/0278-2391(85)90156-9
  30. Brannon RB. The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part II. Histologic features. Oral Surg Oral Med Oral Pathol 1977;43:233-55. https://doi.org/10.1016/0030-4220(77)90161-X
  31. Stoelinga PJ. The treatment of odontogenic keratocysts by excision of the overlying, attached mucosa, enucleation, and treatment of the bony defect with carnoy solution. J Oral Maxillofac Surg 2005;63:1662-6. https://doi.org/10.1016/j.joms.2005.08.007
  32. Tolstunov L, Treasure T. Surgical treatment algorithm for odontogenic keratocyst: combined treatment of odontogenic keratocyst and mandibular defect with marsupialization, enucleation, iliac crest bone graft, and dental implants. J Oral Maxillofac Surg 2008;66:1025-36. https://doi.org/10.1016/j.joms.2007.08.014
  33. Blanas N, Freund B, Schwartz M, Furst IM. Systematic review of the treatment and prognosis of the odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral RadiEndod 2000;9:553-8.
  34. Saulacic N, Stajcic Z, Stojcev Stajcic Lj, Piattelli A, Iizuka T, Lombardi T. Effects of Carnoy's solution on blood vessels of the axillary fossa of rats. Int J Oral Maxillofac Surg 2009;38:876-9. https://doi.org/10.1016/j.ijom.2009.04.001
  35. Morgan TA, Burton CC, Qian F. A retrospective review of treatment of the odontogenic keratocyst. J Oral Maxillofac Surg 2005;63:635-9. https://doi.org/10.1016/j.joms.2004.07.026
  36. Park SH, Kim NK, Kim KH, et al. Postoperative recurrences of odontogenic keratocyst: the behavior and proposal of critical follow-up period. J Korean Assoc Oral Maxillofac Surg 2008;34:456-9.
  37. Tomomatsu N, Uzawa N, Michi Y, Kurohara K, Okada N, Amagasa T. Clinical study of keratocystic odontogenic tumors. J Korean Assoc Oral Maxillofac Surg 2012;38:55-63. https://doi.org/10.5125/jkaoms.2012.38.1.55
  38. Myoung H, Hong SP, Hong SD, et al. Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:328-33. https://doi.org/10.1067/moe.2001.113109