References
- Adelina R, Supriyati MD, Nawangsari DA, Ikawati M, Meiyanto E, (2008a). Efek Estrogenik Ekstrak Etanolik Kulit Jeruk Keprok (Citrus reticulata) dalam Peningkatan Bobot Uterus Tikus Terovariektomi, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 301-309 (In Indonesia).
- Adelina R, Supriyati MD, Nawangsari DA, Jenie RI, Meiyanto E, (2008b). Citrus reticulata Peels Modulate Blood Cholesterol Profile and Increased Bone Density of Ovariectomized Rats. Indonesian J Biotechology, 12, 1092-7.
- Adhami VM, Khan N, Mukhtar H (2009). Cancer Chemoprevention by Pomegranate: Laboratory and Clinical Evidence, Nutr Cancer, 1, 811-5.
- Adina AB, Handoko FF, Setyarini II, et al (2008). Ekstrak Etanolik Kulit Jeruk Nipis (Citrus aurantifolia (Cristm.) Swingle) Meningkatkan Sensitivitas Sel MCF-7 terhadap Doxorubicin, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 55-62, (In Indonesia).
- Akao Y, Itoh T, Ohguchi K, Iinuma M, Nozawa Y (2008). Interactive Effects of Polymethoxy Flavones from Citrus on Cell Growth Inhibition in Human Neuroblastoma SH-SY5Y cells, Bio & Med Chemistry, 16, 2803-10. https://doi.org/10.1016/j.bmc.2008.01.058
- Al-Ashaal HA, El-Sheltawy ST (2011). Antioxidant Capacity of Hesperidin from Citrus Peel Using Electron Spin Resonance and Cytotoxic Activity against Human Carcinoma Cell Lines, Pharm Biol, 49, 276-82. https://doi.org/10.3109/13880209.2010.509734
- Aranganathan S, Nalini N (2009). Efficacy of The Potential Chemopreventive Agent, Hesperetine (Citrus flavanone), on 1,2-Dimethylhydrazine Induced Colon Carcinogenesis, Food Chem Toxicol, 47, 2594-600. https://doi.org/10.1016/j.fct.2009.07.019
- Ardiani M, Puspita N, Gunadi FA, Septisetyani EP, Meiyanto E (2008). Ekstrak Etanolik Kulit Buah Jeruk Mandarin (Citrus Reticulata) Memacu Proliferasi dan Ekspresi Cox-2 pada Sel Kanker Kolon WiDr, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 193-198 (In Indonesia).
- Bastl A, Kaseirov H, Den Hartog GJM, Haenen GRMM, Van Der Vijgh WJF (2007). Protectors Against Doxorubicin-Induced Cardiotoxicity: Flavonoids, Cell Biol Toxicol, 23, 39-47. https://doi.org/10.1007/s10565-006-0139-4
- Bishayee A, Ahmed S, Brankov N, Perloff M (2011), Triterpenoids as Potential Agents for The Chemoprevention and Therapy of Breast Cancer, Front Biosci, 1, 980-96.
- Bocco A, Cuvelier ME, Richard H, Berset C (1998). Antioxidant Activity and Phenolic Composition of Citrus Peel and Seed Extracts, J Agric Food Chem, 46, 2123-9 https://doi.org/10.1021/jf9709562
- Brenner DE (2002). New Paradigms in Oncological Therapeutics: Redefining Combination Chemotherapy, Annals of Oncology, 13, 1697-8. https://doi.org/10.1093/annonc/mdf349
- Broker L, Kruyt FAE, Giaccone G (2005). Cell Death Independent of Caspases: A Review, Clin Cancer Res, 11, 3155-62. https://doi.org/10.1158/1078-0432.CCR-04-2223
- Carpenter (2004). The EGF Receptor Family, Biologic Mechanism and Role in Cancer, Elsevier Academic Press.
- Chen Y, Shen S, Lin H (2003). Rutinoside at C7 Attenuates The Apoptosis-Inducing Activity of Flavonoids, Biochemical Pharmacology, 66, 1139-50. https://doi.org/10.1016/S0006-2952(03)00455-6
- Chiba H, Uehara M, Wu J, et al (2003). Hesperidin, a Citrus Flavonoid, Inhibits Bone Loss and Decreases Serum and Hepatic Lipids in Ovariectomized Mice, J Nutri, 133, 1892-7. https://doi.org/10.1093/jn/133.6.1892
- Choi S, Ko H, Ko S, et al (2007). Correlation between Flavonoid Content and the NO Production Inhibitory Activity of Peel Extracts from Various Citrus Fruits, Biol Pharm Bull, 30, 772-8. https://doi.org/10.1248/bpb.30.772
- Chong PK, Lee H, Zhou J, et al (2010). ITIH3 is a Potential Biomarker for Early Detection of Gastric Cancer, J Proteome Res, 9, 3671-9 https://doi.org/10.1021/pr100192h
- Chrisnanto E, Adelina R, Putri DPP, et al (2008). Antiangiogenic effect of ethanol extract of Citrus reticulata peel in the Chorio Allantoic Membrane (CAM) induced by bFGF, Proceeding, The International Symphosium on Molecular Targeted Theraphy, ISBN:978-979-95107-6-1, 57-66.
- Chung SY, Sung MK, Kim NH, et al (2005). Inhibition of P-Glycoprotein by Natural Products in Human Breast Cancer Cells, Arch Pharm Res, 28, 823-8. https://doi.org/10.1007/BF02977349
- Clayton AJ, Danson S, Jolly S, et al (2004). Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer, Br J Cancer, 91, 639-43. https://doi.org/10.1038/sj.bjc.6601970
- Cragg GM, Newman DJ (2005). Plants as a source of anti-cancer agents, J Ethnopharmacology, 100, 72-9. https://doi.org/10.1016/j.jep.2005.05.011
- Dai Y, Liu M, Tang W, et al (2008). Molecularly Targeted Radiosensitization of Human Prostate Cancer by Modulating Inhibitor of Apoptosis, Clin Cancer Res, 14, 7701-10. https://doi.org/10.1158/1078-0432.CCR-08-0188
- Elmets CA, Viner JL, Pentland AP, et al (2010). Chemoprevention of Nonmelanoma Skin Cancer With Celecoxib: A Randomized, Double-blind, Placebo-Controlled Trial, J National Cancer Institute, 24, 1835-44.
- Epperly MW, Wang H, Jones JA, et al (2011). Antioxidant- Chemoprevention Diet Ameliorates Late Effects of Total- Body Irradiation and Supplements Radioprotection by MnSOD-Plasmid Liposome Administration, Radiat Res, 175, 759-65. https://doi.org/10.1667/RR2398.1
- Fimognari C, Nusse MN, Lenzi M, et al (2006). Sulforaphane Increases The Efficacy of Doxorubicin in Mouse Fibroblasts Characterized by p53 Mutations, Mutation Research, 601, 92-101. https://doi.org/10.1016/j.mrfmmm.2006.06.001
- Fitriasari A, Susidarti RA, Meiyanto E (2010). Peningkatan Efek Sitotoksik Doxorubicin oleh Naringenin pada Sel Kanker Payudara MCF-7, J Bahan Alam Indonesia, 7, 165-70.
- Fong WF, Wang C, Zhu GY, et al (2007). Reversal of Multidrug Resistance in Cancer Cells by Rhizoma Alismatis Extract, Phytomedicine, 14, 160-5. https://doi.org/10.1016/j.phymed.2006.03.004
- Foster I (2008). Cancer: A cell cycle defect, Radiography, 14, 144-9. https://doi.org/10.1016/j.radi.2006.12.001
- Glaeser M, Niederacher D, Djahansouzi S, et al (2006). Effects of the Antiestrogens Tamoxifen and Raloxifene on the Estrogen Receptor Transactivation Machinery, Anticancer Res, 26 725-44.
- Guo BH, Kail GY, Jin HB, Tang KX (2006). Taxol Synthesis, African J Biotechnology, 5, 15-20.
- Hastuti N, Pratiwi D, Armandari I, et al (2008). Ekstrak Etanolik Kulit Jeruk Nipis (Citrus aurantiifollia (Cristm.) Swingle) Menginduksi Apopotosis Pada sel Payudara Tikus Galur Sprague Dawley Terinduksi 7,12- Dimetilbenz[a]antrasena, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 94-99. (In Indonesia).
- Hermawan A, Meiyanto E, Susidarti RA (2010). Hesperidine Increases Cytotoxic Effect of Doxorubicin on MCF-7 Cells, Majalah Farmasi Indonesia, 21, 8-17.
- Hirano T, Abe K, Gotoh M, Oka K (1995). Citrus Flavone Tangeretin Inhibits Leukemic HL-60 Cell Growth Partially through Induction of Apoptosis with Less Cytotoxicity on Normal Lymphocytes, Br J Cancer, 72, 1380-8. https://doi.org/10.1038/bjc.1995.518
- Hirano T, Abe K, Gotoh M, Oka K (1995). Citrus Flavone Tangeretin Inhibits Leukaemic HL-60 Cell Growth Partially Through Induction of Apoptosis With Less Cytotoxicity on Normal Lymphocytes, British J Cancer, 72, 1380-8. https://doi.org/10.1038/bjc.1995.518
- Hirsch FR, Merrick DT, Franklin WA (2002). Role of Biomarkers for Early Detection of Lung Cancer and Chemoprevention, European Respiratory J, 19, 1151-8. https://doi.org/10.1183/09031936.02.00294102
- Huryn DM, Wipf P (2007). Natural Product Chemistry and Anticancer Drug Discovery, in Stephen Neidle, Cancer Drug Design and Discovery, Academic Press, London, 107-130.
- Ishii K, Tanaka S, Kagami K, et al (2010). Effects of Naturally Occurring Polymethyoxyflavonoids on Cell Growth, P-Glycoprotein Function, Cell Cycle, and Apoptosis of Daunorubicin-Resistant T Lymphoblastoid Leukemia Cells, Cancer Investigation, 28, 220-9. https://doi.org/10.3109/07357900902744486
- Johann S, De Oliveira VL, Pizzolatti MG, et al (2007). Antimicrobial Activity of Wax and Hexane Extracts from Citrus spp. Peels, Mem Inst Oswaldo Cruz, 102, 681-5. https://doi.org/10.1590/S0074-02762007005000087
- Jordan CV (2004). Selective Estrogen Receptor Modulation : Concept and Consequences in Cancer, 5:207-13. Jordan, V.C., 2004, Selective Estrogen Receptor Modulation:Concept and Consequences in Cancer, Cancer Cell, l5, 207-13.
- Junedi S, Susidarti RA, Meiyanto E (2010). Peningkatan Efek Sitotoksik Doxorubicin oleh Naringenin pada Sel Kanker Payudara T47D melalui Induksi Apoptosis, J Ilmu Farmasi Indonesia, 8, 85-90.
- Kanno S, Tomizawa A, Hiura A, et al (2005). Inhibitory Effects of Naringenin on Tumor Growth in Human Cancer Cell Lines and Sarcoma S-180-Implanted Mice, Biol Pharm Bull, 28, 527-30. https://doi.org/10.1248/bpb.28.527
- Kiguchi K, Carbajal S, Chan K, et al (2001). Constitutive Expression of ErbB-2 in Gallbladder Epithelium Results in Development of Adenocarcinoma, Cancer Res, 61, 6971-6.
- Kim D, Lee S, Park K, et al (2008). Requirement for Ras/Raf/ ERK Pathway in Naringin-Induced G1-Cell-Cycle Arrest Via p21WAF1 Expression, Carcin, 29, 1701-9. https://doi.org/10.1093/carcin/bgn055
- Kim H, Moon JY, Mosaddik A, Cho SK (2010). Induction of Apoptosis in Human Cervical Carcinoma HeLa Cells by Polymethoxylated Flavone-Rich Citrus grandis Osbeck (Dangyuja) Leaf Extract, Food & Chemical Toxicology, 48, 2435-42. https://doi.org/10.1016/j.fct.2010.06.006
- Kusharyanti I, Larasati, Susidarti RA, Meiyanto E (2011). Hesperidin Increase Cytotoxic Activity of Doxorubicin on HeLa Cell Line Through Cell Cycle Modulation and Apoptotis Induction, Indonesian J Cancer Chemoprevention, 2, 267-73. https://doi.org/10.14499/indonesianjcanchemoprev2iss2pp267-273
- Larasati, Kusharyanti I, Susidarti RA, Meiyanto E (2011). Naringenin Enhances The Anti-Tumor Effect of Doxorubicin on Hela Cervical Cancer Cells Through Cytotoxic Activity and Apoptosis Induction, Indonesian J Cancer Chemoprevention, 2, In Press.
- Lee KW, Bode AM, Dong Z (2011). Molecular Targets of Phytochemicals for Cancer Prevention, Nature Reviews Cancer, 11, 211-8. https://doi.org/10.1038/nrc3017
- Leslie EM, Mao Q, Oleschuk CJ, Deeley RGC, Susan PC (2001) . Modulation of Multidrug Resistance Protein 1 (MRP1/ ABCC1) Transport and ATPase Activities by Interaction with Dietary Flavonoids, Flavonoid Modulation of MRP1 Transport and ATPase Activities, 59, 1171-80.
- Lewis-Wambi JS, Jordan VC (2005). Treatment of Postmenopausal Breast Cancer With Selective Estrogen Receptor Modulators (SERMs). Breast Dis, 24, 93-105.
- Li BB, Smith B, Hossain MM (2006). Extraction of Phenolics from Citrus Peels. I. Solvent Extraction Method, Sep Purif Technol, 48, 182-8. https://doi.org/10.1016/j.seppur.2005.07.005
- Lin JK, Tsai SH (1999), Chemoprevention of Cancer and Cardiovascular Disease by Resveratrol, Proc Natl Sci Counc Repub China B, 23, 99-106.
- Manni A, Xu H, Washington S, et al (2011). The Effects of Tamoxifen and Fish Oil on Mammary Carcinogenesis in Polyoma Middle T Transgenic Mice, Horm Cancer, DOI 10.1007/s12672-011-0078-2.
- Matheny CJM, Lamb MW, Brouwer KLR, Pollack GM (2001) . Pharmacokinetic and Pharmacodynamic Implications of P-glycoprotein Modulation, Pharmacotherapy, 21, 778-96. https://doi.org/10.1592/phco.21.9.778.34558
- Mechetner E, Kyshtoobayeva A, Zonis S, et al (1998). Levels of Multidrug Resistance (MDR1) P-Glycoprotein Expression by Human Breast Cancer Correlate with in vitro Resistance to Taxol and Doxorubicin, Clin Cancer Res, 4, 389-98.
- Meiyanto E, Fitriasari A, Hermawan A, Junedi S, Susidarti RA (2011a). The Improvement of Doxorubicin Activity by Citrus Flavonoid Tangeretin through Cell Cycle Modulation and Apoptotic Induction on Breast Cancer Cell Lines, Oriental Pharmacy and Experimental Medicine, DOI 10.1007/s13596-011-0016-4.
- Meiyanto E, Hermawan A, Junedi S Fitriasari A, Susidarti, RA (2011b). Nobiletin Increased Cytotoxic Activity of Doxorubicin on MCF-7 Cells But Not on T47D Cells, Int J Phytomedicine, 3, 129-37.
- Meyer MR, Haas E, Dan Barton M (2006). Gender Differences of Cardiovascular Disease: New Perspectives for Estrogen Receptor Signaling, Hypertension, 47, 1019-26. https://doi.org/10.1161/01.HYP.0000223064.62762.0b
- Miyamoto S, Yasui Y, Tanaka T, Ohigashi H, Murakami A (2008). Suppressive Effects of Nobiletin on Hyperleptinemia and Colitis-Related Colon Carcinogenesis In Male ICR Mice, Carcinogenesis, 29, 1057-63. https://doi.org/10.1093/carcin/bgn080
- Morley K, Ferguson P, Koropatnick J (2007). Tangeretin and Nobiletin Induce G1 Cell Cycle Arrest but not Apoptosis in Human Breast and Colon Cancer Cells, Cancer Letters, 251, 168-78. https://doi.org/10.1016/j.canlet.2006.11.016
- Murakami A, Nakamura Y, Torikai K, et al (2000). Inhibitory Effect of Citrus Nobiletin on Phorbol Ester-Induced Skin Inflammation, Oxidative Stress and Tumor Promotion in Mice, Cancer Res, 60, 5059-66.
- Nahoum SR (2006). Cancer Mechanisms: Why Cancer and Inflammation? Yale J Bio & Med, 79, 123-30.
- Nahta R, Hortobagya GN, Estevaa FJ (2003). Growth factor receptors in breast cancer: potential for therapeutic intervention, Oncologist, 8, 5-17.
- Nugroho PA, Putri DA, Darma AP, Riyanto S, Meiyanto E (2008) . Penelusuran Mekanisme Penekanan Ekspresi N-Ras Ekstrak Etanolik Kulit Jeruk Keprok (Citrus reticulata) Sebagai Agen Kemopreventif Docking Molekuler pada Protein Target C-SRC dan CYP1A2, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 184-192.(In Indonesia).
- Nugroho PA, Sukamdi DP, Darma AP, Jenie RI, Meiyanto E (2010). Penelusuran Mekanisme Flavonoid Kulit jeruk keprok (Citrus reticulata) Sebagai Agen Kemopreventif Melalui Docking Molekul pada Protein Target CYP1A2, Farmasains, 1, 37-44.
- Ohnishi H, Asamoto M, Tujimura K, et al (2004). Inhibition of Cell Proliferation by Nobiletin, A Dietary Phytochemical, Associated With Apoptosis and Characteristic Gene Expression, But Lack Of Effect on Early Rat Hepatocarcinogenesis In Vivo, Cancer Sci, 95, 936-42. https://doi.org/10.1111/j.1349-7006.2004.tb03180.x
-
Oliver S, Robe P, Bours V (2006). Can NF
${\kappa}B$ be a Target for Novel and Efficient Anti-cancer Agents?, Biochemical Pharmacology, 72, 1054-68. https://doi.org/10.1016/j.bcp.2006.07.023 - Olson RD, Headley MB, Hodzic A, Walsh GM, Wingett DG, (2007). In Vitro and In Vivo Immunosuppre Ssive Activity of a Novel Anthracycline, 13-deoxy, 5-iminodoxorubicin, Int Immuno, 7, 734-43. https://doi.org/10.1016/j.intimp.2007.01.010
- Pan MH, Chen WJ, Shiau SYL, Ho CT, Lin JK (2002). Tangeretin Induced Cell Cycle G1 Arrest through Inhibiting Cyclin-Dependent Kinases 2 and 4 Activities as well as Elevating Cdk Inhibitor p21 and p27 in Human Colorectal Carcinoma Cell, Carcinogenesis, 23, 1677-84. https://doi.org/10.1093/carcin/23.10.1677
- Park JH, Jin CY, Lee BK, et al (2008). Naringenin Induces Apoptosis Through Downregulation of Akt and Caspase-3 Activation in Human Leukemia THP-1 Cells, Food Chem Toxicol, 46, 3684-90. https://doi.org/10.1016/j.fct.2008.09.056
- Pratiwi D, Hastuti N, Armandari I, et al (2008). Ekstrak Etanolik Kulit Jeruk Nipis (Citrus aurantiifollia (Cristm.) Swingle) Meningkatkan Ekspresi p53 Pada Sel Payudara Tikus Galur Sprague Dawley Terinduksi 7, 12- Dimetilbenz[a]antrasena, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 100-106. (In Indonesia).
- Pratomo I, Larasati, Handayani S, et al(2008). Chemoprevention effects of ethanolic extract Keprok Citrus peels (Citrus reticulata) on epithelial mammary and liver cells of Sprague Dawley rats induced by 7,12-Dimethylbenz-[a]anthracene, Proceeding, The International Symphosium on Molecular Targeted Theraphy, ISBN:978-979-95107-6-1, 83-93.
- Puspita N, Ardiani M, Gunadi FA, Septisetyani EP, Meiyanto E (2008). Ekstrak Etanolik Kulit Jeruk Mandarin (Citrus reticulata) Meningkatkan Ekspresi Faktor Angiogenik VEGF pada Sel Kanker Kolon WiDr, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 50-54 (In Indonesia).
- Putri DA, Nugroho PA, Darma AP, et al (2008). Potensi Kemopreventif Ekstrak Etanolik Kulit Jeruk Keprok (Citrus reticulata) pada Sel Kanker Hepar Tikus Galur Sprague Dawley Terinduksi 7, 12-Dimetilbenz[A]antrasena Melalui Penekanan Ekspresi c-Myc, Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 75-80 (In Indonesia).
- Robinson TP, Ehlers T, Hubbard IV, et al (2003). Design, Synthesis, and Biological Evaluation of Angiogenesis Inhibitors: Aromatic Enone and Dienone Analogues of Curcumin, Bioorg Med Chem Lett, 13, 115-7. https://doi.org/10.1016/S0960-894X(02)00832-6
- Rollerova E, dan Urbancikova M (2000). Intracellular Estrogen Receptors, Their Characterization and Function (Review), Endocrine regulations, 34, 203-18.
- Seely D, Mills EJ, Wu Ping, Verma S, Guyatt GH (2005). The Effects of Green Tea Consumption on Incidence of Breast Cancer and Recurrence of Breast Cancer:A Systematic Review and Meta-analysis, Integrative Cancer Therapies, 4, 144-55. https://doi.org/10.1177/1534735405276420
- Shao W, Brown M (2003). Advances in Estrogen Receptor Biology: Prospects for Improvements in Targeted Breast Cancer Therapy, Breast Cancer Research, 6, 39-52. https://doi.org/10.1186/bcr742
- Sharma G, Tyagi AK, Singh RP, Chan DCF, Agarwal R (2004) . Synergistic Anti-Cancer Effect of Grape Seed Extract and Conventional Cytotoxic Agent Doxorubicin Against Human Breast Carcinoma Cells, Breast Cancer Res & Treatment, 85, 1-12. https://doi.org/10.1023/B:BREA.0000020991.55659.59
- Supriyati MD, Adelina R, Nawangsari DA, Ikawati M, Meiyanto E (2008). Modulasi Ekspresi c-Myc Sel Epitelial Kelenjar payudara Tikus oleh Ekstrak Etanolik Kulit Jeruk Keprok (Citrus reticulata), Proceeding, Kongres Ilmiah XVI Ikatan Sarjana Farmasi Indonesia, 70-74. (In Indonesia).
- Tamimi RM, Lagiou P, Adami H, Trichopoulo D (2002). Prospect for Chemoprevention of Cancer, Canc Contr J, 4, 55-64.
- Thompson HJ (2004). DNA Oxidation Products, Antioxidant Status, and Cancer Prevention, J Nutr, 134, 3186-7. https://doi.org/10.1093/jn/134.11.3186S
- Totta P, Acconcia F, Leone S, Cardillo I, Marino M (2004). Mechanisms of Naringenin-Induced Apoptotic Cascade in Cancer Cells: Involvement of Estrogen Receptor Alpha and Beta Signalling, IUBMB Life, 56, 491-9. https://doi.org/10.1080/15216540400010792
- Tsao AS, Kim ES, Hong WK (2004). Chemoprevention of Cancer, CA Cancer J Clin, 54, 150-80. https://doi.org/10.3322/canjclin.54.3.150
- Tumbas VT, Cetkovic GS, Djilas SM, et al (2010). Antioxidant Activity of Mandarin (Citrus reticulata) peel, APTEFF, 41, 195-203.
- Tyagi AK, Agarwal C, Chan DCF, Agarwal R (2004). Synergistic Anti-Cancer Effects of Silibinin with Conventional Cytotoxic Agents Doxorubicin, Cisplatin and Carboplatin against Human Breast Carcinoma MCF-7 and MDA-MB468 Cells. Oncology Reports, 11, 493-9.
- Uliasz A, Spencer JM (2004). Chemoprevention of Skin Cancer and Photoaging, Clinics in Dermatology, 22, 178-82. https://doi.org/10.1016/j.clindermatol.2003.12.012
- Van Slambrouck S, Parmar VS, Sharma SK, et al (2005). Tangeretin Inhibits Extracellular-signal-Regulated Kinase (ERK) Phosphorylation, FEBS Lett, 579, 1665-9. https://doi.org/10.1016/j.febslet.2004.10.114
- Vora T, De azambuja E, Awada A, Piccart M (2009). Novel Therapeutics in Breast Cancer-Looking to The Future, Update on Cancer Therapeutics, 3, 189-205. https://doi.org/10.1016/j.uct.2009.07.001
- Wattanapitayakul SK, Chularojmontri L, Herunsalee A, et al (2005). Screening of Antioxidants from Medicinal Plants for Cardioprotective Effect against Doxorubicin Toxicity, Basic and Clin. Pharmacol & Toxicol, 96, 80-7.
- Yager JD, Davidson NE (2006). Estrogen Carcinogenesis in Breast Cancer, N Engl J Med, 354, 270-82. https://doi.org/10.1056/NEJMra050776
- Yanez JA, Roupe KA, Fukuda C, Teng XW, Davies NM (2004) Stereospecific Disposition and Anti-Cancer Activity of the Chiral Bioflavonoids Hesperetine and Hesperidine in Rodents, Humans, and Fruit Juices, Canadian Society of Pharmaceutical Sciences Annual Meeting, Vancouver, British Columbia, J Pharmacy, 7, 76.
- Yang JY, Ha S, Yang Y, Kim JW (2010). p-Glycoprotein ABCB5 and YB-1 Expression Plays a Role In Increased Heterogeneity of Breast Cancer Cells: Correlations with Cell Fusion and Doxorubicin Resistance, BMC Cancer, 10, 1-10. https://doi.org/10.1186/1471-2407-10-1
- Yi Z, Yu Y, Liang Y, Zeng B (2008). In vitro antioxidant and antimicrobial activities of the extract of Pericarpium Citri Reticulatae of a new Citrus cultivar and its main flavonoids, Food Sci Tech, 41, 597-603.
- Yoshimizu N, Otani Y, Saikawa Y, et al (2004). Anti-tumour Effects of Nobiletin, A Citrus Flavonoid, on Gastric Cancer Include: Antiproliferative Effects, Induction of Apoptosis and Cell Cycle Deregulation, Aliment Pharmacol Ther, 1, 95-101.
- Yunas SR, Latifah N, Rokhman MR, Fitriasari A, Meiyanto E (2007). Penggunaan Ekstrak Etanolik Kulit Buah Jeruk Mandarin (Citrus reticulata) Untuk Meningkatkan Sensitivitas Sel Kanker Payudara MCF-7 Terhadap Agen Kemoterapi Doxorubicin, PHARMACON, 8, 64-69.
- Zhou W, Ercan D, Chen L, et al (2009). Novel Mutant-Selective EGFR Kinase Inhibitors against EGFR T790M, Nature, 24, 1070-4.
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- Multi-Target Cytotoxic Actions of Flavonoids in Blood Cancer Cells vol.16, pp.12, 2015, https://doi.org/10.7314/APJCP.2015.16.12.4843
- Inhibitory Aromatase Effects of Flavonoids from Ginkgo Biloba Extracts on Estrogen Biosynthesis vol.16, pp.15, 2015, https://doi.org/10.7314/APJCP.2015.16.15.6317
- Chemopreventive Actions of Blond and Red-Fleshed Sweet Orange Juice on the Loucy Leukemia Cell Line vol.16, pp.15, 2015, https://doi.org/10.7314/APJCP.2015.16.15.6491
- CYP2D6 Genotype and Risk of Recurrence in Tamoxifen Treated Breast Cancer Patients vol.16, pp.15, 2015, https://doi.org/10.7314/APJCP.2015.16.15.6783
- Anticancer Effect of Citrus Fruit Prepared by Gamma Irradiation of Budsticks vol.25, pp.9, 2015, https://doi.org/10.5352/JLS.2015.25.9.1051
- Simultaneous extraction and biotransformation process to obtain high bioactivity phenolic compounds from brazilian citrus residues vol.31, pp.5, 2015, https://doi.org/10.1002/btpr.2126
- Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells vol.34, pp.1, 2015, https://doi.org/10.3892/or.2015.3982
- Effect of hesperidin on mice bearing Ehrlich solid carcinoma maintained on doxorubicin vol.36, pp.12, 2015, https://doi.org/10.1007/s13277-015-3655-0
- Fisetin suppresses ADAM9 expression and inhibits invasion of glioma cancer cells through increased phosphorylation of ERK1/2 vol.36, pp.5, 2015, https://doi.org/10.1007/s13277-014-2975-9
- Current status and prospects of citrus genomics vol.42, pp.4, 2015, https://doi.org/10.5010/JPB.2015.42.4.326
- Targeting Cancer Stem Cells in Breast Cancer: Potential Anticancer Properties of 6-Shogaol and Pterostilbene vol.63, pp.9, 2015, https://doi.org/10.1021/acs.jafc.5b00002
- Chemopreventive and Therapeutic Potential of “Naringenin,” a Flavanone Present in Citrus Fruits vol.67, pp.1, 2015, https://doi.org/10.1080/01635581.2015.976320
- Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis vol.11, pp.10, 2016, https://doi.org/10.1371/journal.pone.0164115
- Methoxylated flavones: occurrence, importance, biosynthesis vol.15, pp.3, 2016, https://doi.org/10.1007/s11101-015-9426-0
- A microalga, Euglena tuba induces apoptosis and suppresses metastasis in human lung and breast carcinoma cells through ROS-mediated regulation of MAPKs vol.16, pp.1, 2016, https://doi.org/10.1186/s12935-016-0330-5
- Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways vol.37, pp.1, 2016, https://doi.org/10.1007/s13277-015-3774-7
- Naringenin inhibits proliferation, migration, and invasion as well as induces apoptosis of gastric cancer SGC7901 cell line by downregulation of AKT pathway vol.37, pp.8, 2016, https://doi.org/10.1007/s13277-016-5013-2
- Rapid isolation, reliable characterization, and water solubility improvement of polymethoxyflavones from cold-pressed mandarin essential oil vol.39, pp.11, 2016, https://doi.org/10.1002/jssc.201501366
- Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cells vol.5, pp.1, 2015, https://doi.org/10.1038/srep18789
- Korean Byungkyul - Citrus platymamma Hort.et Tanaka flavonoids induces cell cycle arrest and apoptosis, regulating MMP protein expression in Hep3B hepatocellular carcinoma cells vol.50, pp.2, 2017, https://doi.org/10.3892/ijo.2016.3816
- Quantification of Flavonoids in Brazilian Orange Peels and Industrial Orange Juice Processing Wastes vol.08, pp.07, 2017, https://doi.org/10.4236/as.2017.87048
- Flavonoids, Thyroid Iodide Uptake and Thyroid Cancer—A Review vol.18, pp.6, 2017, https://doi.org/10.3390/ijms18061247
- Amelioration of Benzo[a]pyrene-induced oxidative stress and pulmonary toxicity by Naringenin in Wistar rats: A plausible role of COX-2 and NF-κB vol.36, pp.4, 2017, https://doi.org/10.1177/0960327116650009
- Estrogenic Potentials of Traditional Chinese Medicine vol.45, pp.07, 2017, https://doi.org/10.1142/S0192415X17500756
- Naringenin Impairs Two-Pore Channel 2 Activity And Inhibits VEGF-Induced Angiogenesis vol.7, pp.1, 2017, https://doi.org/10.1038/s41598-017-04974-1
- Consumption of fruits, vegetables, and risk of hematological malignancies: a systematic review and meta-analysis of prospective studies vol.59, pp.2, 2018, https://doi.org/10.1080/10428194.2017.1339873
- Intake of dietary flavonoids and risk of epithelial ovarian cancer vol.100, pp.5, 2014, https://doi.org/10.3945/ajcn.114.088708
- Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines vol.6, pp.10, 2016, https://doi.org/10.1016/j.apjtb.2016.08.004
- From folk medicine to functional food: a review on the bioactive components and pharmacological properties of citrus peels vol.18, pp.1, 2018, https://doi.org/10.1007/s13596-017-0292-8
- Suppressive effect of nobiletin and epicatechin gallate on fructose uptake in human intestinal epithelial Caco-2 cells vol.82, pp.4, 2018, https://doi.org/10.1080/09168451.2017.1387515
- Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein vol.19, pp.4, 2018, https://doi.org/10.3390/ijms19041173
- Nobiletin suppresses cell viability through AKT Pathways in PC-3 and DU-145 prostate cancer cells vol.15, pp.1, 2014, https://doi.org/10.1186/2050-6511-15-59
- Metastatik Prostat Kanserinde Nobiletinin Sitotoksik ve Apoptotik Etkisinin Belirlenmesi vol.8, pp.4, 2018, https://doi.org/10.31832/smj.485666
- Safety Evaluation of a New Traditional Chinese Medical Formula, Ciji-Hua’ai-Baosheng II Formula, in Adult Rodent Models vol.2019, pp.1741-4288, 2019, https://doi.org/10.1155/2019/3659890