Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
권호 표지

Hazards Assessment and Workplace Management of Epichlorohydrin

Epichlorohydrin의 유해성과 작업환경 관리

  • Kim, Hyeon-Yeong (Occupational Safety&Health Research Institute, KOSHA) ;
  • Hwang, Yang In (Occupational Safety&Health Research Institute, KOSHA) ;
  • Kuk, Won-Kwen (BioConvergence Technology Laboratory, Korea Conformity Laboratories)
  • 김현영 (한국산업안전보건공단 산업안전보건연구원) ;
  • 황양인 (한국산업안전보건공단 산업안전보건연구원) ;
  • 국원근 (한국건설생활환경시험연구원)
  • Published : 2012.06.30
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Abstract

Objectives: Epichlorohydrin is a material that has been predicted to have high volatility and strong toxicity and is used normally in working area. Therefore, the hazardous and dangerous level and the foreign management system about epichlorohydrin should be invested at home and abroad and through hazard assessment for occupational environment measurement and exposure status of industrial workers in domestic working area. Methods: To assess risk and to suggest Development and Adoption to prevent health damage of workers owing to the epichlorohydrin exposure, the hazardousness and dangerousness of epichlorohydrin and its practical examples and regulation level for domestic and abroad health impairment are researched on the base of various references. Results: The epichlorohydrin caused skin and mucus membrane irritation, respiratory paralysis, kidney and live damage under the influence of acute toxicity and in animal study, it was confirmed as a doubtful carcinogenic substance to trigger reducement of sperm number and reproduction ability, abnormal spermatogenesis, mutagen, increase of forestomach epithelium and occurrence of papilloma and so on, as well as it induced stimulus asthma and allergic contact dermatitis for exposure workers. Conclusions: Epichlorohydrin was found to occur allergic contact dermatitis, carcinogenesis doubt and reproduction toxicity and was verified as a material which would be established reinforcement of management level to care health of handlers, such as denotement dangerousness of skin absorption.

Keywords

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