The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
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Study of the Efficacy and Safety of "adenophorae radix extract" in the Obese Patients or Overweight

비만 및 과체중 환자에 대한 사삼추출물의 유효성 및 안전성 평가

  • Kim, Gi-Tae (Dept. of Internal Medicine, College of Oriental Medicine, Se-Myung University) ;
  • Go, Heung (Dept. of Internal Medicine, College of Oriental Medicine, Se-Myung University) ;
  • Shin, Seon-Mi (Dept. of Internal Medicine, College of Oriental Medicine, Se-Myung University) ;
  • Kim, Hyung-Jun (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University)
  • 김기태 (세명대학교 한의과대학 내과학교실) ;
  • 고흥 (세명대학교 한의과대학 내과학교실) ;
  • 신선미 (세명대학교 한의과대학 내과학교실) ;
  • 김형준 (세명대학교 한의과대학 부인과학교실)
  • Received : 2012.04.27
  • Accepted : 2012.05.15
  • Published : 2012.05.25
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Abstract

Objectives: The purpose of this study is to evaluate the efficacy and biosafety of Adenophorae Radix(AR) extract in obesity or overweight patient. Methods: This study is double-blind, randomized, placebo-controlled intervention Study. 30 patients with BMI $25{\leq}$ and 30> were allotted into two groups at random. In 0, $6^{th}$, $12^{th}$ week, we had checked body weight, waist line, hip line, body fat and abdominal CT scan. In 0, $12^{th}$ week, we also had checked lipid metabolism and biosafety with blood test. Results: AR treatment had a significant effect on suppressing body wight gain (p<0.01) and BMI index(p<0.01). AR treatment reduced plasma TG level but we couldn't find statistical significance. AR treatment had produced no adverse reactions. Conclusions: This study shows that Adenophorae Radix(AR) extract can reduce the weight, BMI. Adenophorae Radix(AR) extract can be used in obesity or overweight patient.

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