Journal of Ginseng Research

The Korean Society of Ginseng (고려인삼학회)
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Protective Effect of Heat-processed Ginseng (Sun Ginseng) in the Adenine-induced Renal Failure Rats

  • Choi, Hyuck-Jae (East-West Medical Research Institute, Kyung Hee University Medical Center) ;
  • Kim, Eun-Jin (College of Pharmacy, Kyung Hee University) ;
  • Shin, Yong-Wook (Department of Agronomy & Medicinal Plant Resources, Gyeongnam National University of Science and Technology) ;
  • Park, Jeong-Hill (College of Pharmacy, Seoul National University) ;
  • Kim, Dong-Hyun (College of Pharmacy, Kyung Hee University) ;
  • Kim, Nam-Jae (East-West Medical Research Institute, Kyung Hee University Medical Center)
  • Received : 2012.01.04
  • Accepted : 2012.05.03
  • Published : 2012.07.15
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Abstract

The effect of orally administered sun ginseng (SG), which is a ginseng processed by steaming, was examined in adenine-induced chronic renal failure rat. SG significantly decreased both blood urea nitrogen and serum creatinine levels, indicating an improvement of renal function. Also, SG significantly increased the urinary excretion of both urea and creatinine. Furthermore it lowered the blood pressure, and inhibited adenine-induced kidney hypertrophy and edema. Based on these findings, SG may ameliorate chronic renal failures.

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References

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