Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
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Effect of fluoride concentration in pH 4.3 and pH 7.0 supersaturated solutions on the crystal growth of hydroxyapatite

pH 4.3과 pH 7.0의 과포화용액에서 불소의 농도가 합성 수산화인회석의 결정 성장에 미치는 영향

  • Shin, Han-Eol (Department of Conservative Dentistry, Yonsei University College of Dentistry) ;
  • Park, Sung-Ho (Department of Conservative Dentistry, Yonsei University College of Dentistry) ;
  • Park, Jeong-Won (Department of Conservative Dentistry, Gangnam Severance Hospital, Yonsei University College of Dentistry) ;
  • Lee, Chan-Young (Department of Conservative Dentistry, Yonsei University College of Dentistry)
  • 신한얼 (연세대학교 치과대학 보존학교실) ;
  • 박성호 (연세대학교 치과대학 보존학교실) ;
  • 박정원 (강남세브란스 치과병원 보존과) ;
  • 이찬영 (연세대학교 치과대학 보존학교실)
  • Received : 2011.12.17
  • Accepted : 2012.01.20
  • Published : 2012.03.01
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Abstract

Objectives: Present study was undertaken to investigate the crystal growth onto synthetic hydroxyapatite (HA) seeds in pH 4.3 and pH 7.0 supersaturated solutions with different fluoride concentrations. Materials and Methods: 8 groups of pH 4.3 and 7.0 calcium phosphate supersaturated solutions were prepared with different fluoride concentrations (0, 1, 2 and 4 ppm). Calcium phosphate precipitates yield crystal growth onto the HA seed surface while solutions flow. For evaluation of crystallizing process, the changes of $Ca^{2+}$, $PO{_4}^{3-}$, $F^-$ concentrations of the inlet and outlet solutions were determined. The recovered solid samples were weighed to assess the amount of minerals precipitated, and finally determined their composition to deduce characteristics of crystals. Results: During the seeded crystal growth, there were significantly more consumption of $Ca^{2+}$, $PO{_4}^{3-}$, $F^-$ in pH 4.3 solutions than pH 7.0 (p < 0.05). As fluoride concentration increased in pH 4.3 solution, $Ca^{2+}$, $PO{_4}^{3-}$, $F^-$ consumption in experimental solutions, weight increment of HA seed, and fluoride ratio in crystallized samples were increased. There were significant differences among the groups (p < 0.05). But in pH 7.0 solution, these phenomena were not significant. In pH 7.0 solutions, analyses of crystallized samples showed higher Ca/P ratio in higher fluoride concentration. There were significant differences among the groups (p < 0.05). But in pH 4.3 solution, there were not significant differences in Ca/P ratio. Conclusions: Crystal growth in pH 4.3 solutions was superior to that in pH 7.0 solutions. In pH 4.3 solutions, crystal growth increased with showed in higher fluoride concentration up to 4 ppm.

Keywords

References

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