Journal of the Korean Data and Information Science Society

The Korean Data and Information Science Society (한국데이터정보과학회)
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Lipid metabolic effects of caffeine using meta-analysis

메타분석을 이용한 카페인의 지질대사효과

  • Kim, Na-Jung (Department of Information and Statistics, Duksung Women's University) ;
  • Choi, Ki-Heon (Department of Information and Statistics, Duksung Women's University)
  • 김나정 (덕성여자대학교 정보통계학과) ;
  • 최기헌 (덕성여자대학교 정보통계학과)
  • Received : 2012.03.30
  • Accepted : 2012.06.07
  • Published : 2012.07.31
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Abstract

The present study was carried out to summarize the effect of caffeine in the lipid metabolic by meta-analysis. The association measure to test effect of caffeine was the Hedges's standardized mean difference (HG). In this particular fixed-effect model of Hedges's standardized mean difference, weight gain, heart weight, serum total lipid, serum triglycerides and liver triglycerides were significantly decreased (p < 0.05). Also, serum HDL cholesterol and serum LDL cholesterol were significantly increased. In this case of heterogeneous variable, random effect model was applied. In this model, weight gain, heart weight, serum total lipid, serum triglycerides, serum LDL cholesterol and liver triglycerides were significantly decreased in caffeine treated group. Also HDL-cholesterol was significantly increased in caffeine treated group.

카페인의 지질대사효과에 대해 알아보고자 헤지의 표준화된 평균차를 이용하여 메타분석을 하였다. 카페인의 투여여부에 따라 실험군과 대조군으로 나눈 후 실험쥐들의 각 기관의 무게, 혈중 콜레스테롤 등 8개 변수를 관심변수로 두었다. 고정효과모형에서는 체중의 감소, 심장무게의 감소, 혈중 총지질의 감소, 혈중 중성지방의 감소, HDL콜레스테롤의 증가, LDL 콜레스테롤의 증가, 간 중성지방의 감소에 유의한 효과를 보였다. 하지만 모두 동질성을 만족하지 않아 랜덤효과모형을 적용한 결과 체중의 감소, 심장무게의 감소, 혈중 총 총지질의 감소, 혈중 중성지방의 감소, HDL 콜레스테롤의 증가, LDL 콜레스테롤의 감소, 간 중성지방의 감소에 유의한 효과를 보였다.

Keywords

References

  1. Choi, K. H. and Kook, S. J. (2008). Meta analysis using MIX, Free Academy, Seoul.
  2. Cho, S. Y. and Park, M. L. and Park, W. H. and Jeong, J. H. (1989). Effect of caffeine and vitamin E on the lipid composition of serum and liver in cholesterol-fed rats. Journal of the Korean Society of Food Science and Nutrition, 18, 53-61.
  3. Choi, M. J. and Lee, J. E. (2008). The effect of dietary caffeine supplementation on plasma and liver lipid concentrations in male rats. Journal of East Asian Society Dietary life, 18, 466-472.
  4. Encyclopedia (2012). http://www.doopedia.co.kr
  5. Kim, M. J. and Choi, K. H. (2010). The anti-diabetic effect of propolis using Hedges' standardized mean difference. Journal of the Korean Data & Information Science Society, 21, 447-459.
  6. Kim, J. E. and Choi, K. H. (2010). A meta analysis for anti-hyperlipidemia effect of soybeans. Journal of the Korean Data & Information Science Society, 21, 651-667
  7. Kook, S. J. and Han, H. K. and Kim, G. H. and Choi, K. H. (2008). The anti-hepatotoxic effect of ginseng in rats: meta-analysis. Journal of the Korean Data & Information Science Society, 19, 937-949.
  8. Herman P. F. and Judith D. (1996). Meta analysis: An Introduction and point of view. Hepatology, 23, 917-928. https://doi.org/10.1002/hep.510230437
  9. Kim, M. H. and Kim, Y. R. and Lee, J Y. and Park B. K. and Kim, M. K. and Choi, M. K. and Kim, A. J. (2008). The effects of caffeine on lipid and mineral content in the serum of rats. Journal of the Korean Society of Food Science and Nutrition, 21, 336-343.
  10. Lee, C. H. and Choi, B. K. and Lee, W. C. and Park, C. I. and Furugawa, Y. and Kimura, S. (1992). Effect of dietary protein level, caffeine and green tea on boy fat deposition in wistar rats. Journal of the Korean Society of Food Science and Nutrition, 21, 595-600.
  11. Park, M. L. and Cho, S. Y. (1993). Effect of dietary vitamin E on lipid metabolism in caffeine-fed rats. Journal of the Korean Society of Food Science and Nutrition, 22, 658-663.
  12. Rothstein, H. R. and Sutton, A. J. and Borenstein, M. (2005). Publication bias in meta-analysis : Prevention, assessment and adjustments, Wiley, England.
  13. Yu, C. H. and Hong, H. O. (1984). The effect of caffeine beverage intake on lipid metabolism of the Rat taking cholesterol supplemented high fat diet. Sangmyung University Home Culture Research, 3, 93-108.
  14. Yun, A. R. and Choi, K. H. (2011). Meta analysis for anti-hyperlipidemia effect of garlic. Journal of the Korean Data & Information Science Society, 13, 1197-1208.
  15. Yun, A. R. and Choi, K. H. (2011). Meta-regression analysis for anti-diabetic effect of green tea. Journal of the Korean Data & Information Science Society, 22, 717-726.

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