DOI QR코드

DOI QR Code

Effect of Green Coffee Bean Extract Supplementation on Body Fat Reduction in Mildly Obese Women

경도비만 여성에서 생커피두 엑기스의 섭취에 의한 체지방 감소 효과

  • Received : 2012.05.21
  • Accepted : 2012.07.19
  • Published : 2012.08.31

Abstract

In previous studies, we performed joint animal studies and clinical trials between Yonsei University and Oryza Oil & Fat Chemical Co. Ltd. We have shown that coffee bean extract has potent anti-obesity and hypotriglyceridemic activities as well as beneficial effects on body fat reduction.In this study, the effects of coffee bean extract (100 mg/capsule) on body fat reduction were evaluated in overweight/obese women (body mass index of 25~30 $kg/m^2$ or body fat > 30%) not diagnosed with any type of disease. Subjects were randomly assigned to a coffee bean extract group (n=10) or placebo group (n=10). We measured anthropometric parameters, abdominal fat distribution by computed tomography and blood components before and after the 8week intervention period. After supplementation, the coffee bean extract group showed body weight (p=0.08), body mass index (p=0.06), hip circumference (p<0.05), and upper waist circumference (p< 0.01). In addition, after 8 weeks, the coffee bean extract group showed a significant decrease in abdominal internal fat area compared to 0 weeks (0 weeks : $155.8cm^2$; 8 weeks : $145.9cm^2$, ${\Delta}$ change : $-9.9cm^2$, respectively). However, there were no significant differences in lipid profiles or serological measurements between the coffee bean extract group and placebo group. The results of our human study demonstrated that coffee bean extract supplementation for 8 weeks has beneficial effects on reducing abdominal internal fat area as well as hip and waist circumferences.

Keywords

References

  1. Acheson KJ, Gremaud G, Meirim I, Montigon F, Krebs Y, Fay LB, Gay LJ, Schneiter P, Schindler C, Tappy L. 2004. Metabolic effects of caffeine in humans:lipid oxidation or futile cycling. Am J Clin Nutr., 79:40-46
  2. Arciero PJ, Bougopoulos CL, Nindl BC, Benowitz NL. 2000. Influence of age on the thermic response to caffeine in women. Metabolism., 49:101-107 https://doi.org/10.1016/S0026-0495(00)90888-6
  3. Bray GA. 2004. Medical consequences of obesity. J Clin Endocrinol Metab., 89:2583-2589 https://doi.org/10.1210/jc.2004-0535
  4. Cho AS, Jeon SM, Kim MJ, Yeo J, Seo KI, Choi MS, Lee MK. 2010. Chlorogenic acid exhibits antiobesity property and improves lipid metabolism in high fat diet induced obese mice. Food Chem. Toxicol., 48:937-943 https://doi.org/10.1016/j.fct.2010.01.003
  5. Despres JP, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C. 1990. Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Arteriosclerosis, 10: 497-511 https://doi.org/10.1161/01.ATV.10.4.497
  6. Farah A, Monteiro M, Donangelo CM, Lafay S. 2008. Chlorogenic acids from green coffee extract are highly bioavailable in humans. J Nutr., 138:2309-2315 https://doi.org/10.3945/jn.108.095554
  7. Greenberg JA, Boozer CN, Geliebter A. 2006. Coffee, diabetes, and weight control. Am. J Clin Nutr., 84: 682-693
  8. Ibrahim M, Blero D, Deviere J. 2010. Endoscopic options for the treatment of obesity. Gastroenterology., 135:2228-2232
  9. Kim, KJ, Park, SK. 2006. Changes in major chemical constituents of green coffee beans during the roasting. Korean J Food Sci Technol., 38: 153-158
  10. Li SY, Chang CQ, Ma FY, Yu CL. 2009. Modulating effects of chlorogenic acid on lipids and glucose metabolism and expression of hepatic peroxisome proliferator activated receptor alpha in golden hamsters fed on high fat diet. Biomed Environ Sci., 22:122-129 https://doi.org/10.1016/S0895-3988(09)60034-9
  11. Ochiai R, Jokura H, Suzuki A, Tokimitsu I, Ohishi M, Komai N, Rakugi H, Ogihara, T. 2004. Green coffee bean extract improves human vasoreactivity. Hypertens Res., 27:731-737 https://doi.org/10.1291/hypres.27.731
  12. Park JY, Kim JY, Lee SP, Lee JH. 2010 The effect of green coffee bean extract supplementation on body fat reduction in overweight/obese women, Korean J Nutr., 43(4):374-381 https://doi.org/10.4163/kjn.2010.43.4.374
  13. Ranheim T, Halvorsen B. 2005. Coffee consumption and human health beneficial or detrimental Mechanisms for effects of coffee consumption on different risk factors for cardiovascular disease and type 2 diabetes mellithus. Mol Nutr Food Res., 49:274-284 https://doi.org/10.1002/mnfr.200400109
  14. Shimoda H, Seki E, Aitani M. 2006. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complement Altern Med., 6:1-9 https://doi.org/10.1186/1472-6882-6-1
  15. Van Dam RM, Feskens EJ. 2002. Coffee consumption and risk of type 2 diabetes mellitus. Lancet., 360: 1477-1478 https://doi.org/10.1016/S0140-6736(02)11436-X
  16. World Health Organization Expert consultation. 2004. Appropriate body mass index for Asian populations and its implications for policy and intervention strategies. Lancet., 363:157-163 https://doi.org/10.1016/S0140-6736(03)15268-3
  17. Zheng G, Sayama K, Okubo T, Juneja LR, Oguni I. 2004. Antiobesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo., 18:55-62

Cited by

  1. Quality Characteristics and Antioxidant Activity of Pan Bread with Green Coffee Bean Powder vol.27, pp.2, 2017, https://doi.org/10.17495/easdl.2017.4.27.2.97