Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지
DOI QR코드

DOI QR Code

Comparison of the lipids levels, C-reactive protein and adiponectin in adolescent male by fat intake

청년기 남성의 지방 섭취 수준에 따른 혈중지질 함량, C-반응성 단백질 및 아디포넥틴 비교

  • Lee, Sung-Hye (Department of Food Science and Nutrition, Soonchunhyang University) ;
  • Park, Mi-Young (Department of Food and Nutrition, Sookmyung Women's University) ;
  • Kim, Soon-Kyung (Department of Food Science and Nutrition, Soonchunhyang University) ;
  • Min, Young-Ki (Department of Physiology, College of Medicine, Soonchunhyang University)
  • 이성혜 (순천향대학교 식품영양학과) ;
  • 박미영 (숙명여자대학교 식품영양학과) ;
  • 김순경 (순천향대학교 식품영양학과) ;
  • 민영기 (순천향대학교 의과대학 생리학교실)
  • Received : 2012.08.01
  • Accepted : 2012.08.16
  • Published : 2012.08.30
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to investigate the relationship between dietary fat intake, anthropometric data, blood lipids, C-reactive protein, and adiponectin in Korean male college students. Forty-eight subjects were divided into 2 groups based on dietary fat intake: UERF (under 30% of energy ratio for fat source), AERF (above 30% of energy ratio for fat souce). We collected dietary intake data using 24-hour dietary recall for 3 days. Anthropometric and biochemical parameters were measured by using standard methods. Segmental body composition analysis was carried out using an 8-electrode multifrequency bioelectrical impedance method of body fat estimation. There was no significant difference in anthropometric data and serum lipid profile between UERF and AERF group. Serum C-reactive protein level was significantly higher in the AERF group compared to the UERF group. Although there was no significant difference in serum adiponectin level between UERF and AERF groups, subjects had lower adiponectin levels. Correlation data show that serum adiponectin level was positively correlated with vegetable intake (p < 0.05). In addition, dietary fat intake had a positive correlation with meat (p < 0.01), whereas a negative correlation with grain (p < 0.01), vegetables (p < 0.05), and fish (p < 0.05). These results suggest that the increased fat intake of non-obese Korean male college students is associated with their increased serum C-reactive protein concentration. Therefore, proper guidelines on fat intake and nutrition education are necessary for the prevention and management of metabolic syndromes.

Keywords

References

  1. Hays NP, Galassetti PR, Coker RH. Prevention and treatment of type 2 diabetes: current role of lifestyle, natural product, and pharmacological interventions. Pharmacol Ther 2008; 118(2): 181-191 https://doi.org/10.1016/j.pharmthera.2008.02.003
  2. Pokorski R. Effect of increasing body weight on morbidity and mortality in South Korea. J Insur Med 2011; 42(2-4): 78-84
  3. Song Y, Park MJ, Paik HY, Joung H. Secular trends in dietary patterns and obesity-related risk factors in Korean adolescents aged 10-19 years. Int J Obes (Lond) 2010; 34(1): 48-56 https://doi.org/10.1038/ijo.2009.203
  4. Ministry of Health & Welfare, Korea Centers for Disease Control and Prevention. Korean Health Statistics 2010: Korea National Health and Nutrition Examination Survey (KNHANES V-1). 2011
  5. Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol 2010; 316(2): 129-139 https://doi.org/10.1016/j.mce.2009.08.018
  6. Scarpellini E, Tack J. Obesity and metabolic syndrome: an inflammatory condition. Dig Dis 2012; 30(2): 148-153 https://doi.org/10.1159/000336664
  7. Falcao-Pires I, Castro-Chaves P, Miranda-Silva D, Lourenço AP, Leite-Moreira AF. Physiological, pathological and potential therapeutic roles of adipokines. Drug Discov Today 2012; 17(15-16): 880-889 https://doi.org/10.1016/j.drudis.2012.04.007
  8. Lee GR, Shin MK, Yoon DJ, Kim AR, Park NW, Yu R, Han IS. Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet (HFD)-induced obese mice. Obesity (Silver Spring). Forthcoming; 2012
  9. Maury E, Brichard SM. Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Mol Cell Endocrinol 2010; 314(1): 1-16 https://doi.org/10.1016/j.mce.2009.07.031
  10. Kim ES, Im JA, Kim KC, Park JH, Suh SH, Kang ES, Kim SH, Jekal Y, Lee CW, Yoon YJ, Lee HC, Jeon JY. Improved insulin sensitivity and adiponectin level after exercise training in obese Korean youth. Obesity (Silver Spring) 2007; 15(12): 3023-3030 https://doi.org/10.1038/oby.2007.360
  11. Cox AJ, Agarwal S, Herrington DM, Carr JJ, Freedman BI, Bowden DW. C-reactive protein concentration predicts mortality in type 2 diabetes: the Diabetes Heart Study. Diabet Med 2012; 29(6): 767-770 https://doi.org/10.1111/j.1464-5491.2011.03560.x
  12. Kengne AP, Batty GD, Hamer M, Stamatakis E, Czernichow S. Association of C-reactive protein with cardiovascular disease mortality according to diabetes status: pooled analyses of 25,979 participants from four U.K. prospective cohort studies. Diabetes Care 2012; 35(2): 396-403 https://doi.org/10.2337/dc11-1588
  13. Ridker PM, Morrow DA. C-reactive protein, inflammation, and coronary risk. Cardiol Clin 2003; 21(3): 315-325 https://doi.org/10.1016/S0733-8651(03)00079-1
  14. Ozuguz U, Ergun G, Isik S, Gokay F, Tutuncu Y, Akbaba G, Berker D, Guler S. Association between C-reactive protein, carotid intima-media thickness and P-wave dispersion in obese premenopausal women: an observational study. Anadolu Kardiyol Derg 2012; 12(1): 40-46
  15. Lee SW, Jo HH, Kim MR, You YO, Kim JH. Association between obesity, metabolic risks and serum osteocalcin level in postmenopausal women. Gynecol Endocrinol 2012; 28(6): 472-477 https://doi.org/10.3109/09513590.2011.633660
  16. Montenegro-Neto AN, da Silva-Simoes MO, de Medeiros AC, Portela Ada S, Ramos de Queiroz Mdo S, Cunha-Montenegro R, Irany-Knackfuss M. The correlation between anthropometric measurements and biochemical cardiovascular risk markers in the hypertensive elderly. Rev Salud Publica (Bogota) 2011; 13(3): 421-432
  17. Balk EM, Lichtenstein AH, Chung M, Kupelnick B, Chew P, Lau J. Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review. Atherosclerosis 2006; 189 (1): 19-30 https://doi.org/10.1016/j.atherosclerosis.2006.02.012
  18. Clifton PM. Diet and C-reactive protein. Curr Atheroscler Rep 2003; 5(6): 431-436 https://doi.org/10.1007/s11883-003-0032-z
  19. Silva FM, de Almeida JC, Feoli AM. Effect of diet on adiponectin levels in blood. Nutr Rev 2011; 69(10): 599-612 https://doi.org/10.1111/j.1753-4887.2011.00414.x
  20. Reis CE, Bressan J, Alfenas RC. Effect of the diet components on adiponectin levels. Nutr Hosp 2010; 25(6): 881-888
  21. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18(6): 499-502
  22. Saito M, Ishimitsu T, Minami J, Ono H, Ohrui M, Matsuoka H. Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors. Atherosclerosis 2003; 167(1): 73-79 https://doi.org/10.1016/S0021-9150(02)00380-5
  23. Srirattana P, Boonyasirinant T. Correlation between high sensitive C-reactive protein and aortic stiffness using magnetic resonance imaging in patients with known/suspected coronary artery disease. J Med Assoc Thai 2012; 95 Suppl 2: S105-S110
  24. Tolmay CM, Malan L, van Rooyen JM. The relationship between cortisol, C-reactive protein and hypertension in African and Causcasian women: the POWIRS study. Cardiovasc J Afr 2012; 23(2): 78-84 https://doi.org/10.5830/CVJA-2011-035
  25. Hong S, Kang YA, Cho BC, Kim DJ. Elevated serum C-reactive protein as a prognostic marker in small cell lung cancer. Yonsei Med J 2012; 53(1): 111-117 https://doi.org/10.3349/ymj.2012.53.1.111
  26. Fung TT, Rimm EB, Spiegelman D, Rifai N, Tofler GH, Willett WC, Hu FB. Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk. Am J Clin Nutr 2001; 73(1): 61-67 https://doi.org/10.1093/ajcn/73.1.61
  27. King DE, Egan BM, Geesey ME. Relation of dietary fat and fiber to elevation of C-reactive protein. Am J Cardiol 2003; 92(11): 1335-1339 https://doi.org/10.1016/j.amjcard.2003.08.020
  28. Lopez-Garcia E, Schulze MB, Fung TT, Meigs JB, Rifai N, Manson JE, Hu FB. Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr 2004; 80(4): 1029-1035 https://doi.org/10.1093/ajcn/80.4.1029
  29. Pirro M, Schillaci G, Savarese G, Gemelli F, Mannarino MR, Siepi D, Bagaglia F, Mannarino E. Attenuation of inflammation with short-term dietary intervention is associated with a reduction of arterial stiffness in subjects with hypercholesterolaemia. Eur J Cardiovasc Prev Rehabil 2004; 11(6): 497-502 https://doi.org/10.1097/00149831-200412000-00009
  30. Maeda N, Takahashi M, Funahashi T, Kihara S, Nishizawa H, Kishida K, Nagaretani H, Matsuda M, Komuro R, Ouchi N, Kuriyama H, Hotta K, Nakamura T, Shimomura I, Matsuzawa Y. PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 2001; 50(9): 2094-2099 https://doi.org/10.2337/diabetes.50.9.2094
  31. Chu SH, Lee MK, Ahn KY, Im JA, Park MS, Lee DC, Jeon JY, Lee JW. Chemerin and adiponectin contribute reciprocally to metabolic syndrome. PLoS One 2012; 7(4): e34710 https://doi.org/10.1371/journal.pone.0034710
  32. McCullough RS, Edel AL, Bassett CM, Lavallee RK, Dibrov E, Blackwood DP, Ander BP, Pierce GN. The alpha linolenic acid content of flaxseed is associated with an induction of adipose leptin expression. Lipids 2011; 46(11): 1043-1052 https://doi.org/10.1007/s11745-011-3619-0
  33. Desmarchelier C, Ludwig T, Scheundel R, Rink N, Bader BL, Klingenspor M, Daniel H. Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition. Br J Nutr 2012; 1-10
  34. Sharma N, Okere IC, Duda MK, Chess DJ, O'Shea KM, Stanley WC. Potential impact of carbohydrate and fat intake on pathological left ventricular hypertrophy. Cardiovasc Res 2007; 73(2): 257-268 https://doi.org/10.1016/j.cardiores.2006.11.007
  35. The Korean Nutrition Society. Dietary reference intakes for Koreans. Seoul; 2010
  36. Jang HB, Lee HY, Han YH, Song J, Kim KN, Hyun T. Changes in food and nutrient intakes of college students between 1999 and 2009. Korean J Community Nutr 2011; 16(3): 324-336 https://doi.org/10.5720/kjcn.2011.16.3.324
  37. Kim SH. A survey on dietary behaviors and liquid consumptions of university students in Kongju of Chungnam province in Korea. Korean J Nutr 2009; 42(4): 327-337 https://doi.org/10.4163/kjn.2009.42.4.327
  38. Basu A, Devaraj S, Jialal I. Dietary factors that promote or retard inflammation. Arterioscler Thromb Vasc Biol 2006; 26(5): 995-1001 https://doi.org/10.1161/01.ATV.0000214295.86079.d1
  39. Spence JD, Jenkins DJ, Davignon J. Dietary cholesterol and egg yolks: not for patients at risk of vascular disease. Can J Cardiol 2010; 26(9): e336-e339 https://doi.org/10.1016/S0828-282X(10)70456-6
  40. Fernandez ML. Effects of eggs on plasma lipoproteins in healthy populations. Food Funct 2010; 1(2): 156-160 https://doi.org/10.1039/c0fo00088d
  41. Choi SN, Chung NY. Bone density, nutrient intake, blood composition and food habits in non-smoking and non-alcohol drinking male university students. Korean J Food Cult 2010; 25(4): 389-399
  42. Jung BM, Oh ES, Choi SM, Cha YS. Survey of alcoholic and nonalcoholic beverage preference in college students of the Chonnam area. Korean J Community Nutr 2001; 6(3): 290-296
  43. Hasselstrom H, Hansen SE, Froberg K, Andersen LB. Physical fitness and physical activity during adolescence as predictors of cardiovascular disease risk in young adulthood. Danish Youth and Sports Study. An eight-year follow-up study. Int J Sports Med 2002; 23 Suppl 1: S27-S31 https://doi.org/10.1055/s-2002-28458
  44. Murthy NS, Mukherjee S, Ray G, Ray A. Dietary factors and cancer chemoprevention: an overview of obesity-related malignancies. J Postgrad Med 2009; 55(1): 45-54 https://doi.org/10.4103/0022-3859.43549