DOI QR코드

DOI QR Code

Biomimetic MIP Terpene Sensors Adding Conductive Polymers

전도성 고분자가 첨가된 생체 모방형 분자 각인 고분자 테르펜 센서

  • Jung, Jae-Hun (Department of Electronic Engineering, Kyungnam University) ;
  • Lee, Sung-Pil (Department of Electronic Engineering, Kyungnam University)
  • Received : 2012.07.17
  • Accepted : 2012.08.17
  • Published : 2012.09.30

Abstract

Biomimetic terpene sensors which have high sensitivity and stability have been fabricated using moleculary imprinted polymer (MIP) technology. Since it is impossible to make a resistive type sensor due to the high resistance of MIP, we improved the sensor by adding conductive polymers. We investigated the sensitivity of resistive type sensors with nano particles depending on the amount of conductive polymers. The MIP membrane contained the methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross linker, which formed specific cavities originated by the target terpene molecules. The mixture of MIP and the conductive polymer was coated on the patterns of interdigit electrodes on the alumina substrate. The fabricated sensors showed their highest specific sensitivities exposed to 500 ppm target gases : limonene 0.055 at 40% of amount of conductive polymers and geraniol $5.84{\times}10^{-4}$ at 20% of amount of conductive polymers. In conclusion, we found that the terpene sensors are affected by the target molecules, functional monomers and the conductive polymers.

Keywords

References

  1. B. P. Tokin, Fitontsid, 2nd ed, Moscow, 1951.
  2. H. Wang and S. Hanash, "Multi-dimensional liquid phase based separations in proteomics", J. Chromatogr. B, Vol. 787, pp. 11-18, 2003. https://doi.org/10.1016/S1570-0232(02)00335-5
  3. R. Sun, H. Yu, H. Luo, and Z.Y. Shen, "Construction and application of a stoichiometric displacement model for retention in chiral recognition of molecular imprinting", J. Chromatogr. A, Vol. 1055, pp. 1-9, 2004. https://doi.org/10.1016/j.chroma.2004.08.161
  4. B. S. Vicente, F. N. Villoslada, and M. C. Moreno- Bondi, "Continuous solid phase extraction and preconcentration of bisphenol A inaqueous samples using molecularly imprinted columns", Anal. Bioanal. Che., Vol. 380, pp. 115-122, 2004. https://doi.org/10.1007/s00216-004-2744-5
  5. W. H. King Jr., "Piezoelectric sorption detector", Anal. Chem., Vol. 36, No. 9, pp. 1735-1739, 1964.. https://doi.org/10.1021/ac60215a012
  6. E. Pasquinet, C. Bouvier, F. Therx-Merland, L. Hairault, B. Lebret, C. Methivier, and C. M. Pradier, "Synthesis and absorption on gold surfaces of a functionalized thiol : elaboration and test of a new nitroaromatic gas sensor", J. Colloid Interf. Sci., Vol. 272, pp. 21-27, 2004. https://doi.org/10.1016/j.jcis.2003.11.025
  7. M. Yamada, and S. S. Shiratori, "Smoke sensor using mass controlled layer-bylayer self-assembly of polyelectrolytes films", Sensors Actuators B, Vol. 64, pp. 124-127, 2000. https://doi.org/10.1016/S0925-4005(99)00494-3
  8. H. Eun and Y. Umezawa, "Sulfate ion sensing based on a quartz-crystal microbalance immobilized with barium sulfate crystals grown on a selfassembled monolayer of phosphorylated 11-mercapto-1- undecanol", Anal. Chim. Acta., Vol. 375, pp. 155- 165, 1998. https://doi.org/10.1016/S0003-2670(98)00502-9
  9. Y. Liu, X. Yu, R. Davidsson, M. Bengtsson, T. Laurell, and J. Emneus, "Quartz crystal biosensor for real-time monitoring of molecular recognition between protein and small molecular medical agents", Biosens. Bioelectron., Vol. 19, pp. 9-19, 2003. https://doi.org/10.1016/S0956-5663(03)00127-1
  10. N. Tsuru, M. Kikuchi, H. Kawaguchi, and S. Shiratori, "A quartz crystal microbalance sensor coated with MIP for bisphenol A and its properties", Thin Solid Films, Vol. 499, pp. 380-385, 2006. https://doi.org/10.1016/j.tsf.2005.07.005
  11. N. Iqbal, G. Mustafa, A. Rehman, A. Biedermann, B. Najafi, P.A. Lieberzeit, and F. L. Dickert, "QCM-arrays for sensing terpenes in fresh and dried herbs via bio-mimetic MIP layers", Sensors, Vol. 10, pp. 6361-6376, 2010. https://doi.org/10.3390/s100706361
  12. K. S. Ryu and C. H. Yo, "The electrical conductivity of polyaniline film depending on the doping temperature", J. Korean Chemical Society, Vol. 45, No. 3, pp. 282-285, 2001.
  13. C. E. Jung, J. H. Chang, K. P. Huh, M. Kim, and B. S. Kim, "The preparation of chiral separation membranes by UV polymerization and its properties", J. Korean Ind. Eng. Chem., Vol. 19, No. 3, pp. 287-294, 2008.

Cited by

  1. Terpene sensor array with bridge-type resistors by CMOS technology vol.87, 2015, https://doi.org/10.1088/1757-899X/87/1/012065