Applied Microscopy

  • 제42권3호
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  • Pages.142-146
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  • 2012
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  • 2287-5123(pISSN)
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  • 2287-4445(eISSN)
한국현미경학회 (Korean Society of Microscopy)
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Distribution of Doublecortin Immunoreactivities in Developing Chick Retina

  • Kim, Young-Hwa (Department of Emergency Medical Technology, College of Public Health Science, Kyungil University) ;
  • Sun, Woong (Department of Anatomy, Division of Brain Korea 21, Biomedical Science, Korea University College of Medicine)
  • 투고 : 2012.08.17
  • 심사 : 2012.09.10
  • 발행 : 2012.09.30
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초록

Doublecortin (DCX) is a microtuble-associated protein that is required for the migration of immature neuroblasts within the chick and mammalian brain. Although it is generally thought that DCX is expressed only in the neuroblasts, some mature neurons maintain DCX expression; for example, horizontal cells in adult rat retina. In this study, we demonstrate that retinal neural progenitors in the early embryonic stage of the chick also expressed DCX, as do developing ganglion cells and horizontal cells in later stages of development. These findings raise the possibility of a role for DCX in retinal neural progenitors, before they become specialized into neuroblasts in the chick.

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참고문헌

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피인용 문헌

  1. Distinct Features of Doublecortin as a Marker of Neuronal Migration and Its Implications in Cancer Cell Mobility vol.10, pp.1662-5099, 2017, https://doi.org/10.3389/fnmol.2017.00199