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The Functionalities and Active Constituents of Olive Oil

올리브유의 기능성과 활성성분

  • Heo, Wan (Department of Food and Biotechnology, Korea University) ;
  • Lee, So Yoon (Department of Food and Biotechnology, Korea University) ;
  • Lim, Su-Young (Department of Food and Biotechnology, Korea University) ;
  • Pan, Jeong Hoon (Department of Food and Biotechnology, Korea University) ;
  • Kim, Hyung Min (Department of Food and Biotechnology, Korea University) ;
  • Kim, Young Jun (Department of Food and Biotechnology, Korea University)
  • 허완 (고려대학교 식품생명공학과) ;
  • 이소윤 (고려대학교 식품생명공학과) ;
  • 임수영 (고려대학교 식품생명공학과) ;
  • 판정훈 (고려대학교 식품생명공학과) ;
  • 김형민 (고려대학교 식품생명공학과) ;
  • 김영준 (고려대학교 식품생명공학과)
  • Received : 2012.05.02
  • Accepted : 2012.08.05
  • Published : 2012.10.31

Abstract

Olive oil is widely consumed in Korea, and is a representative fat source in the Mediterranean diet, known to be effective in the prevention of coronary artery disease. In addition, diverse functionalities have been reported, such as anti-cancer, anti-oxidation, and anti-inflammation effects. In this review, the status of production and variety were investigated with respect to the functionalities of olive oil. The main functional constituents of olive oil are oleic acid, known to improve blood cholesterol, and the minor constituents are polyphenol, tocopherol, squalene, and phospholipid, the concentrations of which can be used to distinguish pressed from refined olive oil. A number of studies of the functionality of olive oil have dealt with the minor constituents, and the beneficial functionalities, such as anti-oxidation, anti-inflammation, and improving blood circulation have been reported. This review intensively investigates the functionalities and the responsible components, and suggests that continual studies on olive oil are necessary for the prevention of various metabolic diseases.

Keywords

References

  1. Bertolini G, Prevost G, Messeri C, Carignani G, Menini VG. Olive germplasm: Cultivars and word-wide collections. Food and Agriculture Organization, Rome, Italy (1998)
  2. Ramirez-Tortosa MC, Urbano G, Lopez-Jurado M, Nestares T, Gomez MC, Mir A, Ros E, Mataix J, Gil A. Extra-virgin olive oil increases the resistance of LDL to oxidation more than refined olive oil in free-living men with peripheral vascular disease. J. Nutr. 129: 2177-2183 (1999) https://doi.org/10.1093/jn/129.12.2177
  3. Visioli F, Galli C, Plasmati E, Viappiani S, Hernandez A, Colombo C, Sala A. Olive phenol hydroxytyrosol prevents passive smoking-induced oxidative stress. Circulation 102: 2169- 2171 (2000) https://doi.org/10.1161/01.CIR.102.18.2169
  4. Montedoro G. I costituenti fenolici presenti negli oli vergini di olive (The phenolic constituents present in virgin olive oils). Sci. Technol. Aliment. 2: 177-186 (1972)
  5. Tsimidou M. Polyphenols and quality of virgin olive oil in retrospect. Int. J. Food Sci. 10: 99-116 (1998)
  6. Aparicio R, Luna G. Characterisation of monovarietal virgin olive oils. Eur. J. Lipid Sci. Tech. 104: 614-627 (2002) https://doi.org/10.1002/1438-9312(200210)104:9/10<614::AID-EJLT614>3.0.CO;2-L
  7. Giovacchino LD, Sestili S, Vincenzo DD. Influence of olive processing on virgin olive oil quality. Eur. J. Lipid Sci. Tech. 104: 587-601 (2002) https://doi.org/10.1002/1438-9312(200210)104:9/10<587::AID-EJLT587>3.0.CO;2-M
  8. Kiritsakis AK. Flavor components of olive oil-a review. J. Am. Oil. Chem. Soc. 75: 673-681 (1998) https://doi.org/10.1007/s11746-998-0205-6
  9. Sies H. Oxidative stress: Oxidants and antioxidants. Exp. Physiol. 82: 291-295 (1997) https://doi.org/10.1113/expphysiol.1997.sp004024
  10. Blekas G, Tsimidou M, Boskou D. Contribution of $\alpha$-tocopherol to olive oil stability. Food Chem. 52: 289-294 (1995) https://doi.org/10.1016/0308-8146(95)92826-6
  11. Visioli F, Galli C, Francis B, Mattei A, Patelli R, Galli G, Caruso D. Olive oil phenolics are dose-dependently absorbed in human. FEBS Lett. 468: 159-160 (2000) https://doi.org/10.1016/S0014-5793(00)01216-3
  12. Owen RW, Mier W, Giacosa A, Hull WE, Spiegelhalder B, Bartsch H. Phenolic compounds and squalene in olive oils: The concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans, and squalene. Food Chem. Toxicol. 38: 647-659 (2000) https://doi.org/10.1016/S0278-6915(00)00061-2
  13. Velasco J, Dobarganes C. Oxidative stability of virgin olive oil. Eur. J. Lipid Sci. Tech. 104: 661-676 (2002) https://doi.org/10.1002/1438-9312(200210)104:9/10<661::AID-EJLT661>3.0.CO;2-D
  14. Pinelli P, Galardi C, Mulinacci N, Vincieri FF, Tattini M, Romani A. Quali-quantitative analysis and antioxidant activity of different polyphenolic extracts from Olea europea L. leaves. J. Commodity Sci. 39: 71-83 (2000)
  15. Geelings A, Leon ELH, Sanchez JCM, Puerta JB, Lopez JJ. Natural products and derivatives thereof for protection against neurodegenerative diseases. U.S. Patent 0,236,202 (2003)
  16. Schaffer S, Podstawa M, Visioli F, Bogani P, Muller WE, Eckert GP. Hydroxytyrosol-rich olive mill wastewater extract protects brain cells in vitro and ex vivo. J. Agr. Food Chem. 55: 5043- 5049 (2007) https://doi.org/10.1021/jf0703710
  17. Schaffer S, Muller WE, Eckert GP. Cytooprotective effects of olive mill wastewater extract and its main constitute hydroxytyrosol in PC12 cells. Pharmacol. Res. 62: 322-327 (2010) https://doi.org/10.1016/j.phrs.2010.06.004
  18. Tuck KL, Freeman MP, Hayball PJ, Stretch GL, Stupans I. The in vivo fate of hydroxytyrosol and tyrosol, antioxidant phenolic constituents of olive oil, after intravenous and oral dosing of labeled compounds to rats. J. Nutr. 131: 1993-1996 (2001) https://doi.org/10.1093/jn/131.7.1993
  19. Des Gachons CP, Uchida K, Bryant B, Shima A, Sperry JB, Dankulich-Nagrudny L, Tominaga M, Smith AB, Beauchamp GK, Breslin PAS. Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal. J. Neurosci. 31: 999-1009 (2011) https://doi.org/10.1523/JNEUROSCI.1374-10.2011
  20. Beauchamp GK, Keast RSJ, Morel D, Lin J, Pika J, Han Q, Lee CH, Smith AB, Breslin PAS. Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil. Nature 437: 45-46 (2005) https://doi.org/10.1038/437045a
  21. Kamal-Eldin A, Appelqvist LA. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31: 671-701 (1996) https://doi.org/10.1007/BF02522884
  22. Boskou D, Morton ID. Changes in the sterol composition of olive oil on heating. J. Sci. Food Agr. 26: 1149-1153 (1975) https://doi.org/10.1002/jsfa.2740260812
  23. Barrera-Arellano D, Ruiz-Mendez V, Velasco J, Marquez-Ruiz G, Dobarganes C. Loss of tocopherols and formation of degradation compounds at frying temperatures in oils differing in degree of unsaturation and natural antioxidant content. J. Sci. Food Agr. 82: 1696-1702 (2002) https://doi.org/10.1002/jsfa.1245
  24. Aguilera Y, Dorado ME, Prada FA, Martinez JJ, Quesada A, Ruiz-Gutierrez V. The protective role of squalene in alcohol damage in the chich embryo retina. Exp. Eye Res. 80: 535-543 (2005) https://doi.org/10.1016/j.exer.2004.11.003
  25. Vitagliano M. I costituenti minori degli olii vegetali (The minor constituents of vegetable olis). Riv. Ital. Sostanze Gr. 36: 46-55 (1961)
  26. Hudson BJF, Ghovami M. Phospholipids as antioxidant synergists for tocopherols in the autoxidation of edible oils. Lebensm.-Wiss. Technol. 17: 191-194 (1984)
  27. Gardner CD, Kraemer HC. Monounsaturated versus polyunsaturated dietary fat and serum lipids. Arterioscl. Thromb. Vas. 15: 1917-1927 (1995) https://doi.org/10.1161/01.ATV.15.11.1917
  28. Chait A, Brazg RI, Tribble DL, Krauss RM. Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B. Am. J. Med. 94: 350-356 (1993) https://doi.org/10.1016/0002-9343(93)90144-E
  29. Libby P. Atherosclerosis: The new view. Sci. Am. 286: 46-55 (2002)
  30. Rudel LL, Parks JS, Sawyer JK. Compared with dietary monounsaturated and saturated fat, polyunsaturated fat protects African green monkeys from coronary artery atherosclerosis. Arteriosc. Thromb. Vas. 15: 2101-2110 (1995) https://doi.org/10.1161/01.ATV.15.12.2101
  31. Nigon F, Lesnik P, Rouis M, Chapman MJ. Discrete subspecies of human low density lipoproteins are heterogeneous in their interaction with the cellular LDL receptor. J. Lipid Res. 32: 1741-1753 (1991)
  32. Galeano NF, Milne R, Marcel YL, Walsh MT, Levy E, Ngu'yen TD, Gleeson A, Arad Y, Witte L, AI Haideri M, Rumsey SC, Deckelbaum RJ. Apoprotein B structure and receptor recognition of triglyceride-rich low density lipoprotein (LDL) is modified in small LDL but not in triglyceride-rich LDL of normal size. J. Biol. Chem. 269: 511-519 (1994)
  33. Navab M, Berliner JA, Watson AD, Hama SY, Territo MC, Lusis AJ, Shih DM, Van Lenten BJ, Frank JS, Demer LL, Edwards PA, Fogelman AM. The Yin and Yang of oxidation in the development of the fatty streak. Arterioscl. Thromb. Vas. 16: 831-842 (1996) https://doi.org/10.1161/01.ATV.16.7.831
  34. Holvoet P, Mertens A, Verhamme P, Bogaerts K, Beyens G, Verhaeghe R, Collen D, Muls E, Van De Werf F. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscl. Thromb. Vas. 21: 844-848 (2001) https://doi.org/10.1161/01.ATV.21.5.844
  35. Carluccio MA, Siculella L, Ancora MA, Massaro M, Scoditti E, Storelli C, Visioli F, Distante A, Caterina RD. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of the Mediterranean diet phytochemicals. Arterioscl. Thromb Vas. 23: 622-629 (2003) https://doi.org/10.1161/01.ATV.0000062884.69432.A0
  36. Moreno JJ. Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7. Free Radical. Bio. Med. 35: 1073-1081 (2003) https://doi.org/10.1016/S0891-5849(03)00465-9
  37. Massaro M, Basta G, Lazzerini G, Carluccio MA, Bosetti F, Solaini G, Visioli F, Paolicchi A, Caterina RD. Quenching of intracellular ROS generation as a mechanism for oleate-induced reduction of endothelial activation in early atherogenesis. Thromb. Haemostasis 88: 335-344 (2002) https://doi.org/10.1055/s-0037-1613207
  38. Petroni A, Blasevich M, Salami M, Papini N, Montedoro GF, Galli C. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil. Thromb. Res. 78: 151- 160 (1995) https://doi.org/10.1016/0049-3848(95)00043-7
  39. Gimeno E, Fito M, Lamuela-Raventos RM, Castellote AI, Covas M, Farre M, De La Torre-Boronat MC, Lopez-Sabater MC. Effect of ingestion of virgin olive oil on human low-density lipoprotein composition. Eur. J. Clin. Nutr. 56: 114-120 (2002) https://doi.org/10.1038/sj.ejcn.1601293
  40. Martin-Moreno JM, Willett WC, Gorgojo L, Banegas JR, Rodriguez- Artalejo F, Fernandez-Rodriguez JC, Maisonneuve P, Boyle P. Dietary fat, olive oil intake and breast cancer risk. Int. J. Cancer. 58: 774-780 (1994) https://doi.org/10.1002/ijc.2910580604
  41. Visioli F, Galli C. The effect of minor constituents of olive oil on cardiovascular disease: New findings. Nutr. Rev. 56: 142-147 (1998)
  42. De La Puerta R, Martinez-Dominguez E, Ruiz-Gutierrez V. Effect of minor components of virgin olive oil on topical anti-inflammatory assays. Z. Naturforsch. 55c: 814-819 (2000)
  43. Llor X, Pons E, Roca A, Alvarez M, Mane J, Fernandez-banares F, Gassull M. The effects of fish oil, olive oil, oleic acid and linoleic acid on colorectal neoplastic processes. Clin. Nutr. 22: 71-79 (2003) https://doi.org/10.1054/clnu.2002.0627
  44. Salvini S, Sera F, Caruso D, Giovannelli L, Visioli F, Saieva C, Masala G, Ceroti M, Giovacchini V, Pitozzi V, Galli C, Romani A, Mulinacci N, Bortolomeazzi R, Dolara P, Palli D. Daily consumption of a high-phenol extra-virgin olive oil reduces oxidative DNA damage in postmenopausal women. Brit. J. Nutr. 95: 742- 751 (2006) https://doi.org/10.1079/BJN20051674
  45. Prieme H, Loft S, Klarlund M, Gronbaek K, Tonnesen P, Poulsen HE. Effect of smoking cessation on oxidative DNA modification estimated by 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion. Carcinogenesis 19: 347-351 (1998) https://doi.org/10.1093/carcin/19.2.347
  46. Willett WC, Sacks F, Trichopoulou A, Drescher G, Ferro-Luzzi A, Helsing E, Trichopoulos D. Mediterranean diet pyramid: A cultural model for healthy eating. Am. J. Clin. Nutr. 61: 1402S-1406S (1995) https://doi.org/10.1093/ajcn/61.6.1402S
  47. Willett WC. The dietary pyramid: dose the foundation need repair? Am. J. Clin. Nutr. 68: 218-219 (1998) https://doi.org/10.1093/ajcn/68.2.218
  48. Roche H, Zampelas A, Knapper JM, Webb D, Brooks C, Jackson KG, Wright J, Gould BJ, Kafatos A, Gibney MJ, Williams CM. Effect of long-term olive oil dietary intervention on postprandial triacylglycerol and factor VII metabolism. Am. J. Clin. Nutr. 68: 552-560 (1998) https://doi.org/10.1093/ajcn/68.3.552
  49. Willcox DC, Willcox BJ, Todoriki H, Suzuki M. The Okinawan diet: Health implications of a low-calorie, nutrient-dense, antioxidant- rich dietary pattern low in glycemic load. J. Am. Coll. Nutr. 28: 550S-516S (2009)
  50. Suzuki M, Wilcox BJ, Wilcox CD. Implication from and for food cultures for cardiovascular disease: Longevity. Asian Pac. J. Clin. Nutr. 10: 165-171 (2001) https://doi.org/10.1046/j.1440-6047.2001.00219.x
  51. Moriguchi EH, Moriguchi Y, Yamori Y. Impact of diet on the cardiovascular risk profile of Japanese immigrants living in Brazil: Contributions of world health organization cardiac and monalisa studies. Clin. Exp. Pharmacol. Physiol. 31: S5-S7 (2004) https://doi.org/10.1111/j.1440-1681.2004.04119.x

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