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Potential Risk Assessment of Cardiovascular Disease in Low Calcium-Score

낮은 칼슘 수치에서 심혈관질환의 잠재 위험도 평가

  • Yoo, Heangsoo (Department of Radiology, Samsungchangwon Hospital) ;
  • Park, Jikoon (Department of Radiological Science, International University of Korea) ;
  • Jung, Bongjae (Department of Radiological Science, International University of Korea) ;
  • Noh, Sicheol (Department of Radiological Science, International University of Korea) ;
  • Choi, IlhHong (Department of Radiological Science, International University of Korea) ;
  • Jung, Hyungjn (Department of Radiological Science, International University of Korea) ;
  • Kang, Sangsik (Department of Radiological Science, International University of Korea)
  • 유행수 (삼성창원병원 영상의학과) ;
  • 박지군 (한국국제대학교 방사선학과) ;
  • 정봉재 (한국국제대학교 방사선학과) ;
  • 노시철 (한국국제대학교 방사선학과) ;
  • 최일홍 (한국국제대학교 방사선학과) ;
  • 정형진 (한국국제대학교 방사선학과) ;
  • 강상식 (한국국제대학교 방사선학과)
  • Received : 2013.06.28
  • Accepted : 2013.12.25
  • Published : 2013.12.25

Abstract

Prepared her for the early detection of the risk of cardiovascular disease prevention for the various attempts being made ill through a lot of research to the criteria of coronary artery calcification, but the figure is more than 100 the progress of the flow can be expected to be was. In this study, we quantify the correlation between body composition analysis, blood lipid levels of calcium and public asymptomatic even at low calcium levels in comparison with the existing studies by analyzing potential risk of cardiovascular disease will be represented on the were evaluated. Studies, the calcium scores in the body composition analysis "1-10", and when "11-100" when there was a significant correlation in BMI and WHR look more normal frequency range of the mean values in the normal range meomulreoteuna 21% relative HDL and TG in lipid profiles, no significant correlation look more normal frequency range of risk were derived from the mean values in the normal range, 21% to 40% of the relative risk were derived. meomulreoteuna. In addition, there is no correlation between BFM and BMR Also, average increases in the frequency of a higher standard was higher relative risk derived 31 to 93%, and geological correlation test TC above 20mg/dl atherosclerotic sclerosis seems to be the value of HDL to act to remove cholesterol from atheroma already looking at the same time to suppress the occurrence of atherosclerosis, increased LDL showed higher values occurs rapidly increasing. At this time, the relative risk of 43-50% have been identified. In other words, even when calcium levels are low, that is inherent in the incidence of cardiovascular disease was unknown.

심혈관 질환의 위험도를 조기에 발견해 예방하기 위한 다양한 시도들이 이루어지고 있는 데 질환자를 대상으로 한 많은 연구를 통해 관상동맥 석회화의 판정기준이 마련되었으나 수치가 100 이상이 되어야 진행의 흐름을 예상할 수 있었다. 이에 본 연구는 자각증상이 없는 일반인을 대상으로 칼슘 수치와 체성분 분석, 혈중지질 수치의 상관관계를 수치화하여 기존 연구와 비교분석하여 칼슘 수치가 낮을 때에도 잠재적인 심혈관 질환의 위험성을 나타낼 수 있을지에 대한 평가를 해 보았다. 연구 결과 체성분 분석에서 칼슘수치가 0-10일 때 와 칼슘수치가 11-100일 때 유의한 상관관계가 있는 BMI와 WHR을 살펴보면 정상범위의 빈도수가 많아 평균값이 정상범위에 머물렀으나 21%의 상대적인 위험률이 도출되었으며 지질검사에서도 유의한 상관관계가 있는 HDL과 TG를 살펴보면 정상범위의 빈도수가 많아 평균값이 정상범위에 머물렀으나 21-40%의 상대적인 위험률이 도출되었다. 또한 상관관계가 없는 BFM과 BMR에서는 표준이상에서 빈도수가 높아 평균값도 높게 나타났으며 상대적 위험도가 31-93%로 도출되었으며 지질검사에서 상관관계가 없는 TC가 200 mg/dl이상으로 죽상동맥경화증의 발생이 급격히 증가하여 LDL값이 높게 나타났으며 죽상경화증의 발생을 억제하기 위해 이미 생긴 죽종에서 콜레스테롤을 제거하는 작용을 하는 HDL의 값도 동시에 증가한 것으로 보인다. 이 때의 상대적 위험률은 43-50%로 도출되었다. 즉 칼슘 수치가 낮을 때에도 심혈관 질환의 발생률이 내재되어 있음을 알 수 있었다.

Keywords

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