DOI QR코드

DOI QR Code

전립샘암의 방사선 치료 시 입체조형치료법와 세기조절방사선 치료법의 비교

A Comparison between Three Dimensional Radiation Therapy and Intensity Modulated Radiation Therapy on Prostate Cancer

  • 김영재 (광양보건대학교 방사선과) ;
  • 이재섭 (광양보건대학교 방사선과) ;
  • 홍성일 (광양보건대학교 방사선과) ;
  • 고혜진 (조선대학교병원 방사선종양학과)
  • Kim, YoungJae (Dept. of Radiological Technology, Gwangyang Health College) ;
  • Lee, JaeSub (Dept. of Radiological Technology, Gwangyang Health College) ;
  • Hong, Seongill (Dept. of Radiological Technology, Gwangyang Health College) ;
  • Ko, HyeJin (Dept. of Radiation Oncology, Chosun University Hospital)
  • 투고 : 2013.10.02
  • 심사 : 2013.12.25
  • 발행 : 2013.12.30

초록

본 연구에서는 전립샘암 환자에게 방사선 치료법인 3차원 입체조형법과 세기조절치료법을 각각 적용 할 경우 선량분포의 차이를 관찰하여 치료기법의 우수성을 평가하고자 하였다. 실험대상자 10명의 컴퓨터 단층 모의치료영상을 얻어 종양학과 전문의가 종양용적 및 정상장기를 구분하고 종양용적에 흡수선량을 80 Gy로 설정한 후 각각 다른 치료계획을 수립하였다. 그 결과 선량분포윤곽은 세기조절치료법이 우수 하였고 종양조직의 흡수선량은 세기조절치료법이 처방선량에 근접(100.2%)하였으며 정상조직 흡수율(방광, 직장, 소장, 좌 우 대퇴골두) 또한 우수하였다. 즉, 전립샘암의 방사선 치료시 세기조절방사선치료가 입체조형치료법보다 선량적인 면에서 양호한 것으로 분석되었다.

In this study, we evaluated to the superiority of treatment techniques on prostate cancer, apply to each other treatment techniques-3D conformal therapy versus IMRT-using dose distribution and dose coverages. Obtained 10 patients CT simulation, divided tumor volume and critical organs. Prescription dose was 80 Gy on tumor volume and Each of plans was set by two different plans. As a result, Dose coverage was superior to IMRT. The IMRT's tumor absorbed dose(100.2%) was close to prescription doses. Normal tissue(bladder, rectal, bowel Lt Rt fumoral head) absorbed dose rate was superior. In other words, the radiation therapy of prostate cancer with intensity modulated radiation therapy was better than conformal radiation therapy on dose.

키워드

참고문헌

  1. Perez CA, Brady LW. "Principles and practice of radiation oncology", 5th ed. Philadelphia, 5th ed, J. B. Lippincott Company, pp. 497-498, 1992.
  2. Carol MP, Grant W, bleier AR, et al. "The fieldmatching problem as I applies to the Peacock three-dimensional conformal system for modulation" Radiat Oncol Biol Phys., Vol. 34, No. 1, pp. 183-187, 1996. https://doi.org/10.1016/0360-3016(95)02044-6
  3. Chao KS, Low DA, Perez CA. "Intensity modulated radiation therapy in head and neck cancers" Radiat Oncol Biol Phy, Vol. 27, No. 1, pp.49-60, 2000.
  4. Mohan R, Wang X, Jackson A. "The potential and limitations of the inverse radiotherapy technique" Radiat and Oncol, Vol. 32, No. 3, pp. 232-48, 1994. https://doi.org/10.1016/0167-8140(94)90023-X
  5. Bortfeld T, Boyer AL. Schlegel W, Kahler DL et al, "Realization and verification of three-dimensional conformal radiotherapy with modulated fields" Radiat Oncol Biol Phys, Vol. 30, No. 4, pp. 899-908, 1994. https://doi.org/10.1016/0360-3016(94)90366-2
  6. Convey DJ, Rosenbioom ME. "The generation of intensity modulated fields for conformal radiotherapy by dynamic collimation" Phys Med Biol, Vol. 37, No. 6, pp. 1359-1374, 1992. https://doi.org/10.1088/0031-9155/37/6/012
  7. Daemaley DP, Khoo VS, Norma AR, "Comparison of radiation side-effects of conformal and conventional radiotherapy in prostate cancer:A randomised trial Lancet" The lancet, Vol. 353, No. 9149, pp. 267-72, 1999. https://doi.org/10.1016/S0140-6736(98)05180-0
  8. Nutting C, Deamaley DP, Webb S "Intensity modulated radiation therapy" A clinical review. British J Radiol, Vol. 73, No. 869, pp. 459-69, 2000. https://doi.org/10.1259/bjr.73.869.10884741
  9. Price R, Hanks E, McNeeley SW et al. "Advantages of using noncoplanar vs axial beam arrangements when treating prostate cancer with intensity-modulated radiation therapy and the step-and shoot delivery method" Int J Radiat Oncol Biol Phys, Vol. 53, No. 1, pp. 236-43, 2002. https://doi.org/10.1016/S0360-3016(02)02736-0
  10. Price R, Murphy S, McNeeley SW. "A method for increased dose corformity and segment reduction for SMLC delivered IMRT treatment of the prostate" Int J Radiat Oncol Biol Phys, Vol. 57, No. 3, pp. 843-52, 2003. https://doi.org/10.1016/S0360-3016(03)00711-9
  11. Perez CA, Brady LW. "Principles and practice of radiation oncology" 5th ed. Philadelphia, 5th ed, J. B. Lippincott Company, pp. 1366-1382, 2008.
  12. Michael T. Milano, Louis S. Constine, Paul Okunieff, "Normal Tissue Tolerance Dose Metrics for Radiation Therapy of Major Organs" Semin Radiat Oncol, Vol. 17, pp. 131-140, 2007.
  13. Sung Kyu Kim, Myung Se Kim, Sang Mo Yun, "Dose distribution of Intensity Modulated Radiation Therapy and 3 Dimensional Conformal Radiation Therapy in Prostate Cancer" Yeungnam University. J. of Med, Vol. 24, No. 2, pp. 538-543, 2007.
  14. Jongnam Song, Youngjae Kim, Seungill Hong, "The usability analysis of 3D-CRT, IMRT, Tomotherapy radiation theraphy on nasopharyngeal cancer", Journal of the Korean Society of Radiology, Vol. 6, No. 5, pp. 365-371, 2012, https://doi.org/10.7742/jksr.2012.6.5.365
  15. Rena Lee, Jihye Lee, Kyungja Lee et al, "Bladder Volume Variations in Patients Receiving Conformal Radiotherapy to Prostate" Korean Association For Radiation Protection, Vol. 33, No. 2, pp. 61-65, 2008.

피인용 문헌

  1. Evaluation of Photoneutron by Hypofractionated Radiotherapy vol.15, pp.12, 2015, https://doi.org/10.5392/JKCA.2015.15.12.347
  2. Evaluation of Metal Artifact Reduction for Orthopedic Implants (O-MAR) on Radiotherapy Treatment Planning vol.8, pp.5, 2014, https://doi.org/10.7742/jksr.2014.8.5.217
  3. 몬테칼로 기법을 이용한 CBCT의 광자선 특성 및 선량 분석 vol.11, pp.3, 2013, https://doi.org/10.7742/jksr.2017.11.3.161
  4. 열가소성 플라스틱 재질과 3D 프린트 필라멘트 재질에 대한 방사선량 분석에 관한 연구 vol.15, pp.2, 2021, https://doi.org/10.7742/jksr.2021.15.2.181