한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제36권4호
  • /
  • Pages.283-289
  • /
  • 2013
  • /
  • 3022-7372(pISSN)
  • /
  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
권호 표지
DOI QR코드

DOI QR Code

사상자 추출물의 자돈 병원성 대장균 억제 효과

The effects of Torilis fructus extracts against enteropathogenic Escherichia coli in Piglets

  • 홍선화 (원광대학교 동물자원개발연구센터) ;
  • 김옥진 (원광대학교 동물자원개발연구센터)
  • Hong, Sunhwa (Center for Animal Resource Development, Wonkwang University) ;
  • Kim, Okjin (Center for Animal Resource Development, Wonkwang University)
  • 투고 : 2013.08.19
  • 심사 : 2013.11.08
  • 발행 : 2013.12.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The antibiotic chemotherapy produces sometimes side effects and fails to eliminate bacterial infection. The occurrence of strains resistant to antibiotics would be expected to increase, and it is nowadays important to search for non-antibiotic substances. We are aimed to evaluate the effects of Torilis fructus extracts against enteropathogenic Escherichia coli (E. coli) in Piglets. The piglets were divided with three groups; Negative control group, E. coli-infected positive control group, and the Torilis fructus extracts treated group with E. coli infection. During the study period, we compared clinical signs, weight increase rate, fecal scores, gross findings between the treated group and non treated group. After necropsy, necropsy findings and histopathological findings were conducted with the comparison between the groups. As the results of this study, the Torilis fructus extracts additive showed the effects on the suppression of E. coli-induced lesions. On the basis of this study results, our data suggest that the Torilis fructus extracts additive have the antimicrobial effects. The Torilis fructus extracts additive could be used as the alternative material for antimicrobial feed additives.

키워드

참고문헌

  1. Anadon A, Martinez-Larranaga MR. 1999. Residues of antimicrobial drug and feed additives in animal products. Regulatory aspects. Livest Prod Sci 59: 183-198. https://doi.org/10.1016/S0301-6226(99)00026-3
  2. Blendinger K. 1997. Hormaonal state and effects of the use of an antiprogestin in bitches with pyometra. J Reprod Fertil Suppl 51: 317-325.
  3. Bonneau M, L.aarveld B. 1999. Biotechnology in animal nutrition, physiology and health. Livest Prod Sci 59: 223-241. https://doi.org/10.1016/S0301-6226(99)00029-9
  4. Buenz EJ, Bauer BA, Schnepple DJ, Wahner-Roedler DL, Vandell AG, Howe CL. 2007. A randomized Phase I study of Atuna racemosa: a potential new anti-MRSA natural product extract. J Ethnopharmacol 114: 371-376. https://doi.org/10.1016/j.jep.2007.08.027
  5. Cromwell GL. 2001. Antimicrobial and promicrobial agents. p. 401. In: Lewis A, Southern L(ed.). Swine Nutrition. 2nd ed. CRC Press, Boca Raton, FL, USA.
  6. Deen J, Dee S, Morrison, RB, Radostits M. 2001. Health and production managemaent in swine herds. pp. 635-764. In: Radostits OM(ed.). Herd Health: Food animal Production Medicine 3th ed. Saunders Co., W.B., Philadelphia.
  7. Koehn FE, Carter GT. 2005. The evolving role of natural products in drug discovery. Nat Rev Drug Discov 4: 206-220. https://doi.org/10.1038/nrd1657
  8. Kunin CM. 1993. Resistance to antimicrobial drugs-a worldwide calcmity. Ann Intern Med 118: 557-561. https://doi.org/10.7326/0003-4819-118-7-199304010-00011
  9. Lee GH, Kang SS, An WG, Lee YS, Kwon YK, Shin SW. 2006. Comparison of immune promotion effects of water-extracted angelicae gigantis, Rehamanniae radix,Paeoniae japonica and Polygoni multiflori radix. Korean J Oriental Physiol Pathol 20: 1507-1515.
  10. Lee HA, Hong SH, Bok NH, Kim BK, Kim MS, Park H, Kim YC, Kim OJ. 2008. Antiviral Effect of Natural Herb Extract WK01 and WK02 against Porcine Epidemic Diarrhea Virus. J Life Sci Nat Res 30: 61-71.
  11. Lim TH, Lee JM, Chang, Cha BJ. 2002. Antifungal activity and identification of an Actinomycetes straun isolated from mummified peaches. Korean J Appl Microbiol Biotechnol 28: 161-166.
  12. Liu CS, Cham TM, Yang CH, Chang HW, Chen CH, Chuang LY. 2007. Antibacterial properties of Chinese herbal medicines against nosocomial antibiotic resistant strains of Pseudomonas aeruginosa in Taiwan. Am J Chin Med 35: 1047-1060. https://doi.org/10.1142/S0192415X07005508
  13. Seo SY, Pang JY, Li RH, Kwon J, Ahn MS, Eun JS. 2009. Effects of the combined extracts of Glycine max Merr. and Glycyrrhiza uralensis on the activity of murine splenocytes and macrophages. Korean J Oriental Physiol Pathol 23: 1385-1391.
  14. Sim JG, Lee JH, Shin TY, Shin HY, Jeong SH, Kim MH, Ku HJ, Park JS. 2010. Anti-inflammatory effects of vegetable soup in murine macrophage RQW 264.7 cells. J Korea Soc Food Sci Nutr 39: 1097-1101. https://doi.org/10.3746/jkfn.2010.39.8.1097
  15. Van LI, Huijsdens X, Tiemersma E, De NA, Van de SN, Beaujean D, Voss A, Kluytmans J. 2007. Emergence of Methicillin- Resistant Staphylococcus aureus of Animal Origin in Humans. Emerg Infect Dis 13: 1834-1839. https://doi.org/10.3201/eid1312.070384

피인용 문헌

  1. 천연물질을 이용한 반추동물 항생제 대체용 친환경 펠렛코팅오일의 개발 vol.23, pp.2, 2013, https://doi.org/10.11625/kjoa.2015.23.2.373