Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지
DOI QR코드

DOI QR Code

A Case of Atypical Adenomatous Hyperplasia of Larger Than 2 cm

  • Park, Bo Mi (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Cho, Min Ji (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Lee, Hyun Seok (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Park, Dong Il (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Park, Myoung Rin (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Kim, Ju Ock (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Lee, Jeong Eun (Department of Internal Medicine, Chungnam National University School of Medicine) ;
  • Lee, Choong Sik (Department of Pathology, Chungnam National University School of Medicine) ;
  • Jung, Sung Soo (Department of Internal Medicine, Chungnam National University School of Medicine)
  • Received : 2012.11.20
  • Accepted : 2013.02.06
  • Published : 2013.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Atypical adenomatous hyperplasia (AAH) has been considered to be a precursor lesion of bronchioloalveolar carcinoma (BAC) and pulmonary adenocarcinoma. It usually coexists with BAC and/or an adenocarcinoma. Chest computed tomography reveals multiple well-defined nodules with ground-glass opacity. Usually, AAH does not exceed 10 mm in size. AAH with extensive involvement on one side of the lung field or one that is larger than 2 cm has not been previously reported. We herein report a case of a 71-year-old nonsmoking female with lung AAH of larger than 2 cm.

Keywords

References

  1. Brambilla E, Travis WD, Colby TV, Corrin B, Shimosato Y. The new World Health Organization classification of lung tumours. Eur Respir J 2001;18:1059-68. https://doi.org/10.1183/09031936.01.00275301
  2. Chapman AD, Kerr KM. The association between atypical adenomatous hyperplasia and primary lung cancer. Br J Cancer 2000;83:632-6. https://doi.org/10.1054/bjoc.2000.1317
  3. Kawakami S, Sone S, Takashima S, Li F, Yang ZG, Maruyama Y, et al. Atypical adenomatous hyperplasia of the lung: correlation between high-resolution CT findings and histopathologic features. Eur Radiol 2001; 11:811-4. https://doi.org/10.1007/s003300000790
  4. Ishikawa H. Pathologic/high-resolution CT correlation of focal lung lesions 5 mm or less in diameter: detection and identification by multidetector-row CT. Nihon Igaku Hoshasen Gakkai Zasshi 2002;62:415-22.
  5. Jung KW, Park S, Kong HJ, Won YJ, Lee JY, Park EC, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2008. Cancer Res Treat 2011;43:1-11. https://doi.org/10.4143/crt.2011.43.1.1
  6. Ishikawa H, Koizumi N, Naito M, Umezu H, Morita T, Nemoto T, et al. High-resolution CT findings of pulmonary atypical adenomatous hyperplasia of 5 mm or less in diameter. Nihon Igaku Hoshasen Gakkai Zasshi 2003;63:311-5.
  7. Park CM, Goo JM, Lee HJ, Lee CH, Kim HC, Chung DH, et al. CT findings of atypical adenomatous hyperplasia in the lung. Korean J Radiol 2006;7:80-6. https://doi.org/10.3348/kjr.2006.7.2.80
  8. Kayser K, Nwoye JO, Kosjerina Z, Goldmann T, Vollmer E, Kaltner H, et al. Atypical adenomatous hyperplasia of lung: its incidence and analysis of clinical, glycohistochemical and structural features including newly defined growth regulators and vascularization. Lung Cancer 2003;42:171-82. https://doi.org/10.1016/S0169-5002(03)00289-7
  9. Bae SH, Jung KJ, Bae JY. Multiple atypical adenomatous hyperplasia mimicking lung to lung metastasis: a case report. Korean J Pathol 2005;39:203-6.
  10. Han AR, Kwon OJ, Kwon YS, Shin J, Koh WJ, Cho EY, et al. An atypical adenomatous hyperplasia presenting as a solitary pulmonary nodule with ground glass opacity. Korean J Med 2007;72(Suppl 2):S221-4.
  11. Lee HS, Choi JS, Seo KH, Na JO, Kim YH, Oh MH, et al. A case of congenital cystic adenomatoid malformation of the lng with atypical adenomatous hyperplasia in adult. Tuberc Respir Dis 2009;66:385-9. https://doi.org/10.4046/trd.2009.66.5.385
  12. Nomori H, Horio H, Naruke T, Suemasu K, Morinaga S, Noguchi M. A case of multiple atypical adenomatous hyperplasia of the lung detected by computed tomography. Jpn J Clin Oncol 2001;31:514-6. https://doi.org/10.1093/jjco/hye103
  13. Seki M, Akasaka Y. Multiple lung adenocarcinomas and AAH treated by surgical resection. Lung Cancer 2007; 55:237-40. https://doi.org/10.1016/j.lungcan.2006.10.007
  14. Pastorino U, Calabro E, Tamborini E, Marchiano A, Orsenigo M, Fabbri A, et al. Prolonged remission of disseminated atypical adenomatous hyperplasia under gefitinib. J Thorac Oncol 2009;4:266-7. https://doi.org/10.1097/JTO.0b013e3181952930
  15. Kishi K, Homma S, Kurosaki A, Tanaka S, Matsushita H, Nakata K. Multiple atypical adenomatous hyperplasia with synchronous multiple primary bronchioloalveolar carcinomas. Intern Med 2002;41:474-7. https://doi.org/10.2169/internalmedicine.41.474