The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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The Influence of Pressure and Time on the Preparation of Gumiganghwal-tang Decoctions

  • Kim, Jung-Hoon (Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine) ;
  • Kim, Seong-Sil (Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine) ;
  • Shin, Hyeun-Kyoo (Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine) ;
  • Seo, Chang-Seob (Herbal Medicine Formulation Research Group, Korea Institute of Oriental Medicine)
  • Received : 2013.09.24
  • Accepted : 2013.12.04
  • Published : 2013.12.30
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Abstract

Objectives: This study compared Gumiganghwal-tang (GGT) decoctions produced using different pressure levels for various extraction times to determine the optimal extraction conditions through hydrogen ion concentration (pH), total soluble solids content (TSSC), extraction yield, and content of chemical compounds. Methods: Decoctions were prepared by the pressure levels of 0 or $1kgf/cm^2$ for 30-180 min. The pH and TSSC were measured, the extraction yield was calculated, and the amounts of the chemical compounds were determined using high performance liquid chromatography. Results: The higher pressure and longer extraction time decreased the pH value, while those conditions increased TSSC and extraction yield: the decoction produced in 180 min by pressurized method showed the minimum value of pH, but maximum values of TSSC and extraction yield. The chemical compounds showed higher amounts in decoctions produced by non-pressurized methods than pressurized methods and their amounts were decreased over the peak extraction time in both pressurized and non-pressurized methods. The results of regression analysis confirmed the correlative influences of the pressure and extraction time on pH, TSSC, and extraction yield. Conclusions: This study suggests that pressure and extraction time influence the compositional constituents in GGT decoctions, and the non-pressurized method for 120 min should be chosen as the optimal extraction condition for the preparation of GGT decoction.

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References

  1. Heo J. Dongeuibogam. Seoul: Namsandang. 2007:380.
  2. Kim JD, Kang YG. National Health Insurance Statistical Yearbook. Seoul: National Health Insurance Corporation, Health Insurance Review & Assessment Service. 2010:3001.
  3. Luthria DL. Influence of experimental conditions on the extraction of phenolic compounds from parsley (Petroselinum crispum) flakes using a pressurized liquid extractor. Food Chemistry. 2008;107(2):74552.
  4. Mokgadi J, Turner C, Torto N. Pressurized hot water extraction of alkaloids in goldenseal. Am J Anal Chem. 2013;4:398403.
  5. Han JS, Li X, Park YJ, Kang SJ, Kim JS, Nam KY, et al. Saponin content and quality for the promotion of white Ginseng water extraction conditions. Korean J Crop Sci. 2009;54(4):45863.
  6. Prasad KN, Yang B, Shi J, Yu C, Zhao M, Xue S, et al. Enhanced antioxidant and antityrosinase activities of longan fruit pericarp by ultra-high-pressure-assisted extraction. J Pharm Biomed Anal. 2010;51:4717.
  7. Kim JH, Ahn SC, Choi SW, Hur NY, Kim BY, Baik MY. Changes in effective components of ginseng by puffing. J Korean Soc Appl Biol Chem. 2008;51:18893.
  8. Kwak EJ. Development of brown colored rice tea with high GABA content. J Korean Soc Food Sci Nutr. 2010;29:12015.
  9. Prasad KN, Yang E, Yi C, Zhao M, Jiang Y. Effects of high pressure extraction on the extraction yield, total phenolic content and antioxidant activity of longan fruit pericarp. Innov Food Sci Emerg Technol. 2009;10:1559.
  10. Kim SH, Kim HK, Yang ES, Lee KY, Kim SD, Kim YC, et al. Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla. Sep Purif Technol. 2010;71:16872.
  11. Rostagno MA, Palma M, Barroso CG. Ultrasound-assisted extraction of isoflavones from soy beverages blended with fruit juices. Anal Chim Acta. 2007; 597:26572.
  12. Liu B, Guo F, Chang Y, Jiang H, Wang Q. Optimization of extraction of evodiamine and rutaecarpine from fruit of Evodia rutaecaroa using modified supercritical $CO_2$. J Chromatogr A. 2010;1217:78339.
  13. Zhong K, Wang Q. Optimization of ultrasonic extraction of polysaccharides from dried longan pulp using response surface methodology. Carbohydr Polym. 2010;80:1925.