Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Effect of scaling and root planing combined with systemic doxycycline therapy on glycemic control in diabetes mellitus subjects with chronic generalized periodontitis: a clinical study

  • Gaikwad, Subodh P. (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre) ;
  • Gurav, Abhijit N. (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre) ;
  • Shete, Abhijeet R. (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre) ;
  • Desarda, Hitesh M. (Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre)
  • Received : 2013.01.15
  • Accepted : 2013.03.05
  • Published : 2013.04.30
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Abstract

Purpose: The purpose of study was to compare glycemic control using glycated hemoglobin levels ($HbA_{1c}$) in diabetic patients with chronic generalized periodontitis (CGP) undergoing scaling and root planing (SRP) with and without systemic doxycycline. Methods: Fifty subjects with type 2 diabetes mellitus ($T_2DM$) and CGP receiving antidiabetic therapy were selected for study. The selected subjects were randomly assigned to two groups (test group [TG] and control group [CG]) comprising 25 patients each. The TG received SRP followed by systemic doxycycline. The CG received treatment with SRP only. The periodontal parameters were recorded at baseline (day zero), and every 1 month for 4 months and included probing depth, clinical attachment level, plaque index, gingival index, and $HbA_{1c}$ level were recorded at baseline (day zero) and at the end of 4 months. Results: A statistically significant effect was demonstrated for the periodontal parameters for both the TG and CG. $HbA_{1c}$ values did not show a statistically significant difference in the treatment group as compared to the CG. Conclusions: The authors concluded that nonsurgical periodontal therapy improved glycemic control in patients with $T_2DM$ in both groups, but no statistical difference was observed with adjunctive systemic doxycycline therapy. A further study with a larger sample size is required.

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References

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