A Comparison of Collection Concentrations Based on Airborne Toluene Diisocyanates Measurement Methods

공기 중 Toluene diisocyanates 측정방법에 따른 포집농도 비교

  • Park, Hyung-Sung (Safety and Environment Team, Kia motors Gwangju Plant) ;
  • Won, Jong-Uk (Institute for Occupational Health & Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Kim, Chi-Nyon (Institute for Occupational Health & Graduate School of Public Health, Yonsei University) ;
  • Roh, Jaehoon (Institute for Occupational Health & Department of Preventive Medicine, Yonsei University College of Medicine)
  • 박형성 (기아자동차 광주공장 안전환경팀) ;
  • 원종욱 (연세대학교 의과대학 예방의학교실 및 산업보건연구소) ;
  • 김치년 (연세대학교 보건대학원 및 산업보건연구소) ;
  • 노재훈 (연세대학교 의과대학 예방의학교실 및 산업보건연구소)
  • Published : 2013.12.31

Abstract

Objectives: The aim of this study is to investigate the differences in airborne TDI concentrations based on the filter collection method and liquid collection method and to compare airborne TDIs concentrations by sampling method change when using the filter collection method in the spray-painting process. Methods: For the sample measurement, the filter collection method(OSHA#42) and liquid collection method(NIOSH#5522) were used; for the sampling method, the full-period single sampling and full-period consecutive sampling methods were used. The samples were collected in spray-painting and drying process locations. Results: In all samples collected from the spray-painting and drying process locations through the filter collection and liquid collection methods, greater amounts of 2,6-TDI than 2,4-TDI were detected. When the TDI collection concentrations based on the sampling methods were compared, the concentrations of 2,4-TDI and 2,6-TDI collected by the consecutive sampling method were higher than the concentrations of 2,4-TDI and 2,6-TDI collected by the single sampling method for both the filter collection method and liquid collection method used in the spray-painting process. These differences were statistically significant. Conclusions: When TDI collection concentrations based on the sample measurement methods were compared, the concentration of 2,4-TDI and 2,6-TDI collected through the liquid collection method were higher than the concentrations of 2,4-TDI and 2,6-TDI collected by the filter collection method, and the differences were statistically significant. In the drying process, no difference was shown in the collection concentrations of 2,4-TDI and 2,6-TDI with the two measurement methods.

Keywords

References

  1. ACGIH. Threshold limit values for chemical substances and physical agents & biological exposure indices, Cincinnati. Ohio, ACGIH; 2013
  2. Baur X, Marek W, Ammon J, Czuppon AB, Marczynski B, Raulf-heimsoth M, Roemmelt H, Fruhmann G. Respiratory and other hazards of isocyanates. Int Arch Occup Environ Health 1994; 66:141-152 https://doi.org/10.1007/BF00380772
  3. Bello D, Streiche RP, Liu YC, Sparer J, Youngs F, Woskie SR. Field comparison of impingers and treated filters for sampling of total aliphatic isocyanates with the MAP reagent. J Occup Environ Hyg 2002;63:790-796
  4. Bernstein JA. An overview of diisocyanate-occupational asthma. J Toxicol 1996;111:181-189 https://doi.org/10.1016/0300-483X(96)03375-6
  5. Christian M, Christian HL, Hakan T. Underestimation of toluene diisocyanate concentration using long-term sampling with 1-(2-methoxyphenyl) piperazine impregnated filters. Int J Hyg Environ Health 2008;211:458-462 https://doi.org/10.1016/j.ijheh.2007.08.003
  6. Czamecki B. Polyisocyanate aerosol sampling using coated-filter vs. impinger collection system. Poster presented at AIHCEs, Boston; 1992
  7. Maitre A, Leplay A, Perdrix A, Ohi G, Boinay P, Romazini S, Aubrun JC. Comparison between solid sampler and impinger for evaluation of occupational exposure to 1,6-hexamethylene diisocyanate polyisocyanates during spray painting. J Occup Environ Hyg 1996; 57:153-160
  8. HSE. Methods for the determination of hazardous substances #25/3 organic isocyanates in air (MDHS 25/3). HSE, 1999
  9. IARC. Monographs on the evaluation of carcinogenic risk of chemicals to humans; Some chemicals used in plastics and elastomers. IARC 1999; 71: 865
  10. Kim DI, Kim HR, Park HS, Park SG, Lim JH, Roh JH, Kim JG, Yoon BK, Kim CW. TDI-induced Asthma and Immune Responses in TDI-exposed Workers. Korean J Allergy Clin Immunol 2005;25(4):75-85
  11. Kang HK, Kim HU. Assessment of total isocyanates by OHSA and NIOSH analytical methods: accuracy and precision and airbone concentrations by process. Korean Ind Hyg Assoc J 1999;9(2):1-18
  12. Kim HR, Kim CW, Hong YC, Chun HJ, Kim CN, Kim HS, Lee JN, Shin JY, Koh DH, Roh JH. The Prevalence of Occupational Asthma in TDI-Exposed Workers. Korean J Occup Environ Med 2004;16 (2):191-199
  13. Littorin M, Axmon A, Broberg K, Sennbro CJ, Tinnerberg H. Eye and airway symptoms in low occupational exposure to toluene diisocyanate. Scand J Work Environ Health 2007;33(4):280-285 https://doi.org/10.5271/sjweh.1144
  14. MoEL. Exposure limits for chemical substances and physical Agents(MoELPublic Notice No. 2013-38); 2013
  15. NIOSH. NIOSH Manual of analytical methods(NMAM). 4th Edition, Method 5521, Cincinnati, OH, NIOSH; 1994
  16. NIOSH. NIOSH Manual of analytical methods(NMAM). 4th Edition, Method 5522, Cincinnati, OH, NIOSH; 1998
  17. NTP. Report on Carcinogens. U.S. Department of Health and Human Services, Public Health Service, NTP; 2005
  18. Nordqvist Y, Nilsson U, Colmsjo A. Evaluation of denuder sampling for a mixture of three common gaseous diisocyanates. Anal Bioanal Chem 2003;375:786-791 https://doi.org/10.1007/s00216-003-1784-6
  19. OSHA. Code of federal regulations. part 1910, 1000, table z-1 Limits for air Contaminants; 1996
  20. OSHA. Diisocyanate analytical methods. Method 42, OSHA; 1989
  21. Park HS, Park JN, Kim JW, Kim SK. Clinical and immunological evaluation of isocyanate exposed workers. J Korean Med Sci 1992;7(2):122-127 https://doi.org/10.3346/jkms.1992.7.2.122
  22. Rando RJ, Hassan M, Hammad YY. Isomeric composition of airborne TDI in the polyurethane form industry. J Occup Environ Hyg 1984;45:199-203
  23. Sango C, Zimerson E. A new regaent for determination of isocyanates in working atmospheres by HPLC using UV or Fluorescence detection. J Liq Chromatogr 1980;3(7):971-990 https://doi.org/10.1080/01483918008060208
  24. Tsai CJ, Lin HC, Shin TS, Chang KC, Hung IF, Deshpande CG. Measurement of 2,4-toluene diisocyanate concentrations by different samplers. J Hazard Mater 2006;137:1395-1401 https://doi.org/10.1016/j.jhazmat.2006.04.032