Korean Journal of Fisheries and Aquatic Sciences (한국수산과학회지)

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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Antifouling Activity of Coumarin and its Derivatives Isolated from the Cinnamon Tree Cinnamomum loureiroi

계피식물(Cinnamomum loureiroi)에서 분리한 coumarin과 유도체의 방오효과

  • Kim, Young Do (Department of Marine Biotechnology, Soonchunhyang University) ;
  • Shin, Hyun Woung (Department of Marine Biotechnology, Soonchunhyang University) ;
  • Cho, Ji Young (Department of Marine Biotechnology, Soonchunhyang University)
  • 김영도 (순천향대학교 해양생명공학과) ;
  • 신현웅 (순천향대학교 해양생명공학과) ;
  • 조지영 (순천향대학교 해양생명공학과)
  • Received : 2012.09.24
  • Accepted : 2013.02.13
  • Published : 2013.02.28
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Abstract

The active antifouling compounds coumarin and its derivatives were isolated from the cinnamon tree Cinnamomum loureiroi. The antifouling activities were determined using representative soft fouling organisms: the seaweed Ulvapertusa and diatom Navicula annexa. The chemical constituents with antifouling activities were identified as coumarin, hydroxylcoumarin, coumaric acid, and cinnamaldehyde by interpreting nuclear magnetic resonance, and high-resolution mass spectroscopy data. These compounds were isolated from 1.09 g of crude Cinnamomum sp. methanol extract, yielding approximately 18.4, 6.3, 9.8, and 14.7 mg of coumarin, hydroxylcoumarin, coumaric acid, and cinnamaldehyde, respectively. The compounds inhibited U. pertusa zoospores with $EC_{50}$ values of $0.13-0.25{\mu}g/mL$, and the diatom N. annexa with $EC_{50}$ of $0.21-0.81{\mu}g/mL$.

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References

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