Journal of Ginseng Research

The Korean Society of Ginseng (고려인삼학회)
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HPLC-based metabolic profiling and quality control of leaves of different Panax species

  • Yang, Seung-Ok (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Lee, Sang Won (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Kim, Young Ock (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Sohn, Sang-Hyun (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Kim, Young Chang (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Hyun, Dong Yoon (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Hong, Yoon Pyo (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration) ;
  • Shin, Yu Su (Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration)
  • Received : 2012.04.12
  • Accepted : 2012.07.16
  • Published : 2013.04.15
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Abstract

Leaves from Panax ginseng Meyer (Korean origin and Chinese origin of Korean ginseng) and P. quinquefolius (American ginseng) were harvested in Haenam province, Korea, and were analyzed to investigate patterns in major metabolites using HPLC-based metabolic profiling. Partial least squares discriminant analysis (PLS-DA) was used to analyze the the HPLC chromatogram data. There was a clear separation between Panax species and/or origins from different countries in the PLS-DA score plots. The ginsenoside compounds of Rg1, Re, Rg2, Rb2, Rb3, and Rd in Korean leaves were higher than in Chinese and American ginseng leaves, and the Rb1 level in P. quinquefolius leaves was higher than in P. ginseng (Korean origin or Chinese origin). HPLC chromatogram data coupled with multivariate statistical analysis can be used to profile the metabolite content and undertake quality control of Panax products.

Keywords

References

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