Objectives A descriptive, comparative study was performed using female college students as experimental subjects. The objective was to compare the pulse waves of experimental subjects having severe menstrual pain and control subjects having minor or no menstrual pain. Methods The subjects of this experiment were female college students and the data were collected from September 2011 to February 2012. During normalcy, these data were gauged a week to ten days after menstruation, and during menstruation, they were gauged two to three days after the start of menstruation, when the menstrual pain was at its peak. Results The results was as follows. 1. Right Chuk Ap of the menstrual period was significantly narrowed than usual period. In comparison of Ap on menstrual pain group and non menstrual pain group, Left Kwan Ap showed significant difference. 2. Left Chon $h_1$ and Right Chuk $h_1$ of the menstrual period was significantly lowered than usual period. Right Kwan $h_1$ was appeared significant difference between menstrual pain group and non menstrual pain group. 3. Left Chon Wm of the menstrual period was appeared significantly short than usual and left Kwan Wm of the menstrual period was appeared significantly long than usual. Conclusions Ap, $h_1$ and Wm of the menstrual period were changed in Qwan and Chuk. Ap, $h_1$ and Wm of the menstrual pain group were appeared significant difference than non menstrual pain group.