Journal of Acupuncture Research

  • 제30권3호
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  • Pages.75-85
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  • 2013
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  • 2586-288X(pISSN)
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  • 2586-2898(eISSN)
대한침구의학회 (Korean Acupuncture & Moxibustion Medicine Society)
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정향약침(丁香藥鍼)이 고지방 식이 유발 비만 백서(白鼠)에 미치는 영향

The Effects of Pharmacopuncture(Eugenia caryophyllata $T_{HUNB.}$) on the High Fat Diet-induced Obese ICR Mice

  • 김성진 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 이현종 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 이봉효 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 이윤규 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 임성철 (대구한의대학교 한의과대학 침구경혈학교실) ;
  • 정태영 (제한동의학술원) ;
  • 김재수 (대구한의대학교 한의과대학 침구경혈학교실)
  • Kim, Sung Jin (Department of Acupuncture & Moxibustion, Meridian & Acupoint, Colleage of Oriental Medicine, Daegu Hanny University) ;
  • Lee, Hyun Jong (Department of Acupuncture & Moxibustion, Meridian & Acupoint, Colleage of Oriental Medicine, Daegu Hanny University) ;
  • Lee, Bong Hyo (Department of Acupuncture & Moxibustion, Meridian & Acupoint, Colleage of Oriental Medicine, Daegu Hanny University) ;
  • Lee, Yun Kyu (Department of Acupuncture & Moxibustion, Meridian & Acupoint, Colleage of Oriental Medicine, Daegu Hanny University) ;
  • Lim, Seong Chul (Department of Acupuncture & Moxibustion, Meridian & Acupoint, Colleage of Oriental Medicine, Daegu Hanny University) ;
  • Jung, Tae Young (Je-Han Oriental Medical Academy) ;
  • Kim, Jae Soo (Department of Acupuncture & Moxibustion, Meridian & Acupoint, Colleage of Oriental Medicine, Daegu Hanny University)
  • 투고 : 2013.05.11
  • 심사 : 2013.05.29
  • 발행 : 2013.06.20
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초록

Objectives : The purpose on this study is to show the anti-obesity effect of Eugenia caryophyllata $T_{HUNB.}$ pharmacopuncture in mice fed a high fat diet. Methods : Male ICR mice were divided into three groups, which were fed a normal AIN diet(N), a high fat diet(CT), a high fat diet and injected with 50 mg/kg of Eugenia caryophyllata $T_{HUM.}$ pharmacopuncture(EC) for 8 weeks. Results : 1. The levels of body weight gains were significantly increased in CT compared with N and decreased in EC compared with CT. 2. The levels of absolute liver weight and adipose-tissue weight were significantly decreased in EC compared with CT. The levels of relative adipose-tissue weight were significantly decreased in EC compared with CT. 3. The levels of total cholesterol(TG), triglycerid(TC), high density lipoprotein(HDL) cholesterol and low density lipoprotein(LDL) cholesterol were significantly increased in CT compared with N and decreased in EC compared with CT. The levels of HDL/LDL ratio were shown there were no significant differences in all groups. 4. The levels of adiponectin in serum were remarkably decreased in CT compared with N and significantly increased in EC compared with CT. 5. The levels of measuring adipocyte number in adipose tissue was significantly decreased in CT compared with N and increased in EC compared with CT. Conclusions : These results suggest that Eugenia Caryophyllata $T_{HUNB.}$ has an anti-obesity effect in mice and that the effect is mediated by inhibition of fat gain.

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