Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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GafChromic RTQA Film Dosimetry for Laser Beam with Photodynamic Therapy

GafChromic RTQA Film을 이용한 광역학적 치료용 레이저의 선질 측정

  • Lee, Byung Koo (Department of Biomedical Engineering, College of Medicine, Chungnam National University) ;
  • Lim, Hyun Soo (Department of Biomedical Engineering, College of Medicine, Chungnam National University) ;
  • Kenar, Necla (Department of Biomedical Engineering, College of Medicine, Chungnam National University)
  • Received : 2013.03.18
  • Accepted : 2013.06.04
  • Published : 2013.04.30
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Abstract

Purpose: The purposes of this study were to measure the dose distribution of Photodynamic therapy(PDT) laser with 635 nm wavelength using GafChromic film. Method & Result: We made each output 300 J by changing mW and sec using the laser beam radiation mode such as C.W(Continuous Wave) mode, Pulse mode and Burst Pulse mode and measured the does at 0 mm and 5 mm of distance from optic fiber catheter end to the film, and at 5 mm distance by changing the angle of the end of the optic fiber catheter as $0^{\circ}$ and $0.5^{\circ}$. The radiated film was scanned and OD(Optical Density) was compared. And two-dimensional isodose curves were obtained and the consistency of shapes was compared. It was confirmed that there was consistency between optic density and the dose radiated on the film when we radiated GafChromic film by changing distance and angle of 300 J output in each radiation mode coordinating mW and sec. Conclusion: In this study, we could identify the stability according to changes in laser beam modes, changes in output according to distance, changes in uniformity according to angle, and beam profiles using GafChromic film, and we could also get two-dimensional isodose curve. It was found that small change in the distance and angle that is made when optic fiber catheter was contacted on the treatment area did not make big effects on the output of beam and the uniformity of dose, and it was also found that GafChromic film could be utilized for the purpose of QA of PDT laser beam.

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References

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