Progress in Medical Physics (한국의학물리학회지:의학물리)

Korean Society of Medical Physics (한국의학물리학회)
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Image Evaluation Via $SUV_{LBM}$ for Normal Regions of VOI by Using Whole Body Images Obtained from PET/MRI and PET/CT

F-18 FDG PET/MRI와 PET/CT 전신 영상에서 VOI를 이용한 정상부위의 $SUV_{LBM}$-최대치에 의한 영상평가

  • Park, Jeong-Kyu (Department of Radiologic Technology, Daegu Health College) ;
  • Kim, Sung-Kyu (Department of Therapeutic Radiology & Oncology, Yeungnam University College of Medicine) ;
  • Cho, Ihn-Ho (Department of Nuclear Medicine, Yeungnam University College of Medicine) ;
  • Kong, Eun-Jung (Department of Nuclear Medicine, Yeungnam University College of Medicine) ;
  • Park, Meyong-Hwan (Department of Radiologic Technology, Daegu Health College)
  • 박정규 (대구보건대학교 방사선과) ;
  • 김성규 (영남대학교 방사선종양학교실) ;
  • 조인호 (영남대학교 핵의학교실) ;
  • 공은정 (영남대학교 핵의학교실) ;
  • 박명환 (대구보건대학교 방사선과)
  • Received : 2013.02.18
  • Accepted : 2013.03.05
  • Published : 2013.03.31
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Abstract

The purpose of this research is to compare and analyze $SUV_{LBM}$-maximum of normal regions using VOI (the volume of interest) in order to enhance the diagnostic level in whole body images of PET/CT and PET/MRI for 26 health check-up participants. In particular, we try to set up $SUV_{LBM}$-maximum data that can be used in synchronous evaluation for PET/CT and PET/MRI without contrast media. The evaluation of $SUV_{LBM}$-maximum for normal regions of whole body PET/CT and whole body PET/MRI shows that the image of PET/MRI differs very significantly from the reference image of PET/CT (p<0.0001). However, they exhibit high correlations in view of statistics (R>0.8). From this research, we suggest that the decision in the evaluation of $SUV_{LBM}$-maximum for PET/MRI should be made with the reduction of about 26.3%, while one should decide with the reduction of about 29.3% when the contrast media is used. It is helpful to interpret all image of PET/CT and PET/MRI using $SUV_{LBM}$-maximum for convenience and efficiency.

본 연구의 목적은 26명의 건강한 검진자들을 대상으로 PET/CT와 PET/MRI의 전신 영상에서 조기 정밀/ 진단 수준을 향상하고자 관심부피를 이용하여 정상부위의 $SUV_{LBM}$-최대치를 이용하여 PET/CT와 PET/MRI를 조영제 사용 유무와 관계없이 동시 평가할 수 있는 데이터를 구축하고자 하였다. 전신 F-18 FDG PET/CT와 전신 F-18 FDG PET/MRI의 정상부위의 VOI를 이용한 $SUV_{LBM}$-최대치평가는 PET/CT를 기준으로 PET/MRI의 영상은 매우 유의한 차이를 보였다(p<0.0001). 그러나 통계학적으로 높은 상관관계를 가진다(R>0.8). PET/MRI의 $SUV_{LBM}$ 평가 시 26.3% 감소하여 판단할 것과 조영제를 사용할 경우는 29.3% 감소하여 판단할 것으로 생각한다. PET/CT와 PET/MRI의 모든 영상의 판독에서는 $SUV_{LBM}$-최대치를 사용하는 것이 편리성과 효율성을 고려하여 임상의나 연구자들에게 많은 도움이 되리라 판단된다.

Keywords

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