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Cellmed Orthocellular Medicine and Pharmaceutical Association (셀메드 세포교정의약학회)
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Review on the ethnomedicinal, phytochemical and pharmacological properties of Piper sarmentosum: scientific justification of its traditional use

  • Seyyedan, Atefeh (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia) ;
  • Yahya, Farhana (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia) ;
  • Kamarolzaman, Mohammad Fauzi Fahmi (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia) ;
  • Suhaili, Zarizal (Faculty of Agriculture and Biotechnology, Universiti Sultan Zainal Abidin, Kampus Kota) ;
  • Desa, Mohd Nasir Mohd (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia) ;
  • Khairi, Hussain Mohd (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia) ;
  • Somchit, Muhammad Nazrul (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia) ;
  • Fatimah, Corazon Abdullah (Institute of Bio-IT Selangor, Universiti Selangor) ;
  • Teh, Lay Kek (Pharmacogenomics Centre (PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA) ;
  • Salleh, Mohd Zaki (Pharmacogenomics Centre (PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA) ;
  • Zakaria, Zainul Amiruddin (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia)
  • Received : 2013.02.03
  • Accepted : 2013.08.20
  • Published : 2013.08.31
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Abstract

Piper sarmentosum is a creeping herb belongs to the family of Piperaceae. It is locally known to the Malays as 'Pokok kadok' and can be found in different regions of South-East Asia including Malaysia. Ethnopharmacologically, various parts of the plant (e.g. leave, fruit and root) are widely used in Asian countries for centuries to treat different types of diseases and ailments such as hypertension, diabetes, joint aches, muscle pain, coughs, influenza, toothaches and rheumatism. Scientific findings also demonstrated different pharmacological actions of various parts of P. sarmentosum such as adulticidal, antitermite, antioxidant, antifungal, antituberclosis, antiplasmoid, antimalarial, hypoglycemia, antiinflammatory, antinoceptive, antipyretic, antibacterial, anticancer, antituberculosis, antiangiogenesis, antimicrobial, antifeedant and cytotoxic activities. Different types of phytochemical constituents have been successfully identified and isolated from various parts of P. sarmentosum. Therefore, the information related to the botany, ethnomedicinal uses, phytochemical constituents and pharmacological activities of P. sarmentosum were reviewed here.

Keywords

References

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