Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of Far-Infrared Irradiation on the Antioxidant and Tyrosinase Inhibitory Activities of Extracts from Schizonepeta tenuifolia

형개 추출물의 항산화 활성 및 Tyrosinase 저해 활성에 대한 원적외선 처리의 효과

  • Received : 2013.05.15
  • Accepted : 2013.07.27
  • Published : 2013.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

The objective of this study was to evaluate the effects of far-infrared (FIR) irradiation on the antioxidant and tyrosinase inhibitory activities of Schizonepeta (S.) tenuifolia. After FIR irradiation of S. tenuifolia for 30 min at 70, 90, or $110^{\circ}C$, water extracts (2 g/100 mL) were prepared at $60^{\circ}C$ for 1, 3, or 5 h. Total phenol content (TPC), 1,1-diphenyl-2-picryl-hydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activities (RSAs), and tyrosinase inhibitory activity of the extracts were determined. TPC, antioxidant and tyrosinase inhibitory activities of the extracts increased significantly with increasing FIR irradiation temperature of S. tenuifolia. For example, irradiation at $110^{\circ}C$ for 5 h increased TPC, DPPH RSA, ABTS RSA, and tyrosinase inhibitory activity of the extract from 204.64 to $618.67{\mu}g$ gallic acid equivalents/mL, from 30.15 to 80.84%, from 24.43 to 55.33%, and from 7.05 to 33.65%, respectively, compared to the extract of untreated S. tenuifolia. These results indicate that FIR irradiation may be useful as a processing method for enhancing the quality of S. tenuifolia.

형개(Schizonepeta tenuifolia) 2 g을 70, 90, $110^{\circ}C$에서 30분간 원적외선 처리 후 물 100 mL와 함께 $60^{\circ}C$에서 1, 3, 5시간 추출하였다. 원적외선을 고온에서 처리함에 따라 추출물의 항산화 활성 및 tyrosinase 저해능이 증가하였다. 시료에 원적외선을 처리하였을 때 무처리구에 비해서 항산화능 및 tyrosinase 저해능이 증가하였으며, 특히 고온에서 원적외선을 처리할수록 좋은 활성을 보였다. 총 페놀 함량, DPPH 라디칼 소거능, ABTS 라디칼 소거능, tyrosinase 저해능이 $110^{\circ}C$에서 원적외선을 처리하였을 때 각각 약 2.5, 2.6, 2.3, 4.4배 증가하였고, 추출시간이 항산화 활성과 tyrosinase 저해능에 미치는 영향은 크지 않았다. 이러한 형개 추출물의 생리적 활성은 페놀성 화합물에 근거한 것으로 생각되며 형개를 건강기능식품이나 미백화장품의 소재로서 적용하고자 할 때 원적외선 처리는 매우 긍정적인 영향을 미칠 것으로 여겨진다.

Keywords

References

  1. Fujita S, Fujita Y. 1973. Miscellanous contributions to the essential oils of plants from various territories. XXXII. On the components of the essential oils of Schizonepeta tenuifolia Briq. Yakugaku Zasshi 93: 1622-1626. https://doi.org/10.1248/yakushi1947.93.12_1622
  2. Mun JY. 2011. Distinction and phylogenetic analysis of Citri unshiu semen, Schizonepetae spike and Prunella spike on the basis of DNA sequences. PhD Dissertation. Kyunghee University, Seoul, Korea.
  3. Qiu Q, Ling J, Ding Y, Chang H, Wang J, Liu T. 2005. Comparison of supercritical fluid extraction and steam distillation methods for the extraction of essential oils from Schizonepeta tenuifolia Briq. Se Pu 23: 646-650.
  4. Kirby AJ, Schmidt RJ. 1997. The antioxidant activity of Chinese herbs for eczema and of placebo herbs-I. J Ethnopharmacol 56: 103-108. https://doi.org/10.1016/S0378-8741(97)01510-9
  5. Tohda C, Kakihara Y, Komatsu K, Kuraishi Y. 2000. Inhibitory effects of methanol extracts of herbal medicines on substance P-induced itch-scratch response. Biol Pharm Bull 23:599-601. https://doi.org/10.1248/bpb.23.599
  6. Yoon MY, Lee HJ, Lee BB, Lee SM, Kim JY, Kim Y, Park E, Park HR. 2007. Protective effect of Schizonepeta tenuifolia Briquet extracts on oxidative DNA damage in human leucocytes and on hydrogen peroxide-induced cytotoxicity in PC12 cells. Food Sci Biotechnol 16: 858-862.
  7. Halliwell B, Gutteridge JM. 1984. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 219: 1-14. https://doi.org/10.1042/bj2190001
  8. Cross CE, Halliwell B, Borish ET, Pryor WA, Ames BN, Saul RL, McCord JM, Harman D. 1987. Oxygen radicals and human disease. Ann Intern Med 107: 526-545. https://doi.org/10.7326/0003-4819-107-4-526
  9. Sun B, Fukuhara M. 1997. Effects of co-administration of butylated hydroxytoluene, butylated hydroxyanisole and flavonoids on the activation of mutagens and drug-metabolizing enzymes in mice. Toxicology 122: 61-72. https://doi.org/10.1016/S0300-483X(97)00078-4
  10. Hirose M, Takesada Y, Tanaka H, Tamano S, Kato T, Shirai T. 1998. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat medium-term multi-organ carcinogenesis model. Carcinogenesis 19: 207-212. https://doi.org/10.1093/carcin/19.1.207
  11. Namiki M. 1990. Antioxidants/antimutagens in food. Crit Rev Food Sci Nutr 29: 273-300. https://doi.org/10.1080/10408399009527528
  12. Pokorny J. 1991. Natural antioxidant for food use. Trends Food Sci Technol 2: 223-227. https://doi.org/10.1016/0924-2244(91)90695-F
  13. Jayaprakasha GK, Negi PS, Sikder S, Rao LJ, Sakariah KK. 2000. Antibacterial activity of Citrus reticulata peel extracts. Z Naturforsch C 55: 1030-1034.
  14. Inoue S, Kabaya M. 1989. Biological activities cause by far-infrared radiation. Int J Biometeorol 33: 145-150. https://doi.org/10.1007/BF01084598
  15. Lee SC, Kim JH, Jeong SM, Kim DR, Ha JU, Nam KC, Ahn DU. 2003. Effect of far-infrared radiation on the antioxidant activity of rice hulls. J Agric Food Chem 51: 4400-4403. https://doi.org/10.1021/jf0300285
  16. Lee SC, Jeong SM, Kim SY, Park HR, Nam KC, Ahn DU. 2006. Effect of far-infrared radiation and heat treatment on the antioxidant activity of water extracts from peanut hulls. Food Chem 94: 489-493. https://doi.org/10.1016/j.foodchem.2004.12.001
  17. Gutfinger T. 1981. Polyphenols in olive oil. J Am Oil Chem Soc 58: 966-968. https://doi.org/10.1007/BF02659771
  18. Jeong SM, Kim SY, Park HR, Lee SC. 2004. Effect of farinfrared radiation on the antioxidant activity of extracts from Citrus unshiu peels. J Korean Soc Food Sci Nutr 33: 1580-1583. https://doi.org/10.3746/jkfn.2004.33.9.1580
  19. Pellegrini N, Re R, Yang M, Catherine RE. 1999. Screening of dietary carotenoids and carotenoid-rich fruit extracts for antioxidant activities applying 2,2'-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid) radical cation decolorization assay. Methods Enzymol 299: 379-389. https://doi.org/10.1016/S0076-6879(99)99037-7
  20. Vanni A, Gastaldi D, Giunata G. 1990. Kinetic investigation on the double enzymatic activity of the tyrosinase mushroom. Ann Chim 80: 35-60.
  21. Ahn SI, Bok JH, Son JY. 2007. Antioxidative activity and nitrite-scavenging abilities of some phenolic compounds. Korean J Food Cookery Sci 23: 19-24.
  22. Park JH, Jin JH, Kim HJ, Park HR, Lee SC. 2005. Effect of far-infrared irradiation on the antioxidant activity of extracts from rice hulls. J Korean Soc Food Sci Nutr 34: 131-134. https://doi.org/10.3746/jkfn.2005.34.1.131
  23. Lee SC, Kim SY, Jeong SM, Park JH. 2006. Effect of far-in-frared irradiation on catechins and nitrite scavenging activity of green tea. J Agric Food Chem 54: 399-403. https://doi.org/10.1021/jf051866x
  24. Ji CK. 2004. The characteristics and effects of far-infrared. Living Books, Seoul, Korea. p 40-64.
  25. Lee JH, Lee SR. 1994. Analysis of phenolic substances content in Korean plant foods. Korean J Food Sci Technol 26:310-316.
  26. Jo EK, Lee SC. 2011. Antioxidant and acetylcholinesterase inhibitory activities of subcritical water extracts from Houttuynia cordata Thunb. J Korean Soc Food Sci Nutr 40:1391-1396. https://doi.org/10.3746/jkfn.2011.40.10.1391
  27. Kim DO, Lee KW, Lee HJ, Lee CY. 2002. Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. J Agric Food Chem 50: 3713-3717. https://doi.org/10.1021/jf020071c
  28. Jeong HR, Kwak JH, Kim JH, Choi GN, Jeong CH, Heo HJ. 2010. Antioxidant and neuronal cell protective effects of an extract of Houttuynia cordata Thunb (a culinary herb). Korean J Food Preserv 17: 720-726.
  29. Kim YJ, Uyama H. 2005. Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. Cell Mol Life Sci 62: 1707-1723. https://doi.org/10.1007/s00018-005-5054-y
  30. Chan EWC, Lim YY, Wong LF, Lianto FS, Wong SK, Lim KK, Joe CE, Lim TY. 2008. Antioxidant and tyrosinase inhibition properties of leaves and rhizomes of ginger species. Food Chem 109: 477-483. https://doi.org/10.1016/j.foodchem.2008.02.016
  31. Wang KH, Lin RD, Hsu FL, Huang YH, Chang HC, Huang CY, Lee MH. 2006. Cosmetic applications of selected traditional Chinese herbal medicines. J Ethnopharmacol 106:353-359. https://doi.org/10.1016/j.jep.2006.01.010
  32. Boissy RE, Manga P. 2004. On the etiology of contact/ occupational vitiligo. Pigment Cell Res 17: 208-214. https://doi.org/10.1111/j.1600-0749.2004.00130.x
  33. Hwang EY, Kim DH, Hwang JY, Kim HJ, Park TS, Lee IS, Son JH. 2012. A study on the depigmenting effect of Carthamus tinctorius seed, Cyperus rotundus and Schizonepeta tenuifolia extracts. Korean J Food Sci Technol 44: 76-81. https://doi.org/10.9721/KJFST.2012.44.1.076
  34. Hirota A, Taki S, Kawaii S, Yano M, Abe N. 2000. 1-Diphenyl-2-picrylhydrazyl radical-scavenging compounds from soybean miso and antiproliferative activity of isoflavones from soybean miso toward the cancer cell lines. Biosci Biotechnol Biochem 64: 1038-1040. https://doi.org/10.1271/bbb.64.1038

Cited by

  1. Effects of -decoction Water-extract on Anti-inflammation, Anti-oxidation and Skin Whitening vol.32, pp.3, 2015, https://doi.org/10.13045/acupunct.2015044
  2. SD rats의 성별에 따른 형개 열수추출물의 방사선 방호효과 vol.15, pp.3, 2021, https://doi.org/10.7742/jksr.2021.15.3.313