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Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran

  • Rassouli, Maryam (Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Razmi, Golam Reza (Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Movassaghi, Ahmad Reza (Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Bassami, Mohammad Reza (Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad) ;
  • Sami, Mehrdad (Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad)
  • Received : 2012.06.23
  • Accepted : 2012.11.14
  • Published : 2013.03.31

Abstract

The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (${\kappa}=0.73$, 0.8) and with no significant difference among different fetal age groups (p > 0.05).

Keywords

References

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