Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지
DOI QR코드

DOI QR Code

Subcorneal pustular dermatosis in a dog

개에서 발생한 각질하 농포성 피부병 1례

  • Park, Seong-Jun (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University)
  • 박성준 (충남대학교 수의과대학동물의과학연구소)
  • Received : 2012.11.02
  • Accepted : 2012.12.13
  • Published : 2013.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Canine Subcorneal pustular dermatosis (CSPD) represents a sterile, superficial, pustular skin disease of unknown cause but may be a variant of pemphigus foliaceus. A 7-year-old, intact female, mixed dog presented with 3-month history of pruritic multiple pustules and crusts. Direct smears from intact pustules revealed numerous nondegenerate neutrophils, some acantholytic cells, and bacterial culture was negative. Histologic examination of lesional skin showed subcorneal pustules filled with neutrophils and acantholytic cells. The direct immunofluorescence tests stained with IgG, IgA, IgM, C3 were negative. Oral administration of dapsone (1 mg/kg/q8h) was initiated and it was reduced to 1 mg/kg/q12h with good control of the lesions.

Keywords

References

  1. Cameron H, Dawe RS. Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) treated with narrowband(TL-01) UVB phototherapy. Br J Dermatol 1997, 137, 150-151. https://doi.org/10.1111/j.1365-2133.1997.tb03721.x
  2. Gross TL, Ihrke PJ, Walder EJ, Affolter VK. Pustular disease of the epidermis. In: Skin disease of the dog and cat: clinical and histopathological diagnosis. 2nd ed. pp. 19-20, Blackwell science, Oxford, 2005.
  3. Hnilica KA. Autoimmune and immune-mediated skin disorders. In: Small animal dermatology: a color atlas and therapeutic guide, 3rd ed. pp. 257, Saunders, St. Luis, 2011.
  4. Kalaher KM, Scott DW. Subcorneal pustular dermatosis in dogs and in human beings: comparative aspects. J Am Acad Dermatol, 1990, 22, 1023-1028. https://doi.org/10.1016/0190-9622(90)70145-8
  5. Marliere V, Beylot-Barry M, Beylot C, Doutre M. Successful treatment of subcorneal pustular dermatosis (Sneddon-Wilkinson disease) by acitretin: report of a case. Dermatology, 1999, 199, 153-155. https://doi.org/10.1159/000018224
  6. Muller GH, Scott DW, Miller Jr. WH, Griffin CE. Muller & Kirk's small animal dermatology. 6th ed. pp. 1125-1128, WB Saunders, Philadelpia, 2001.
  7. Paterson S. Miscellaneous skin diseases in the dog. In: Manual of skin diseases of the dog and cat. 2nd ed. pp. 292-293, Blackwell, Oxford, 2008.
  8. Plumb DC. Dapsone. In: Plumb's veterinary drug handbook. 6th ed. pp. 338-340, Wiley-Blackwell, Iowa, 2008.