Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Metastatic thyroid C-cell carcinoma in a beagle dog

  • Lee, So-Ra (Irion Animal Hospital) ;
  • Lee, Mi-Kyoung (Irion Animal Hospital) ;
  • Youp, Kyoung-A (Irion Animal Hospital) ;
  • Lee, Ah-Ra (Irion Animal Hospital) ;
  • Won, Sung-Jun (Irion Animal Hospital) ;
  • Kim, Myung-Chul (The Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, So-Yeon (The Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Yongbaek (The Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University)
  • Received : 2013.04.05
  • Accepted : 2013.07.18
  • Published : 2013.09.30
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Abstract

An adult beagle dog was presented with a cervical mass detected by palpation and computed tomography. Fine needle aspirates revealed numerous epithelial cells with plasmacytoid appearance and frequent naked nuclei. Histologically, the mass consists of multiple packets of neoplastic cells and extensive areas of necrosis and fibrosis. Neoplastic cells were also found in submandibular lymph nodes. Immunohistochemistry showed that neoplastic cells were positive for calcitonin and negative for thyroglobulin. Based on these findings, the cervical mass was diagnosed as thyroid C-cell carcinoma. Almost one year after the surgical excision, the dog remains healthy without any symptom of recurrence or metastasis.

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References

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