Failure of Reproduction Management in an Inbreeding English Bulldog

근친교배 잉글리쉬 불독에서 번식 관리의 실패

  • Kim, Min-Jung (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Park, Sol-Ji (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Geon-A (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Park, Eun-Jung (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Moon, Joon-Ho (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Choi, Ji-Yei (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Choi, Woo-Jae (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Byeong-Chun (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University) ;
  • Jang, Goo (Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University)
  • 김민정 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 박솔지 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 김건아 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 박은정 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 문준호 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 최지예 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 최우재 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 이병천 (서울대학교 수의학과 수의산과 및 생명공학) ;
  • 장구 (서울대학교 수의학과 수의산과 및 생명공학)
  • Accepted : 2013.08.04
  • Published : 2013.10.31

Abstract

A two-year-old, female English bulldog was referred for breeding by artificial insemination with frozen semen of male English bulldog, a litter of female bulldog's grandfather. Intrauterine artificial insemination was done two days after the ovulation day. Sperm was evaluated after thawing by computer assisted sperm analyzer, and its motility was 89.8% with normal shape. Pregnancy bearing eight fetuses was diagnosed by ultrasonography and radiography. Cesarean section was performed sixty days after the artificial insemination. Eight pups were delivered with safe, but the entire pup had abnormalities including severe bow-legged malformations, cleft lip, cleft palate, and enlarged cranial part.

2년령 암컷 잉글리쉬 불독이 근친 유래의 동결정액을 이용한 인공수정을 위해 내원하였다. 배란 후 이틀 뒤 자궁 내 인공수정을 실시하였다. 정액을 해동 후 컴퓨터 기반의 정액 분석기를 사용하여 평가한 결과, 해동된 정자는 정상 모양을 가지고 있었고 운동성이 89.8%였다. 초음파와 방사선 촬영을 통하여 8마리를 임신한 것을 확인하였고, 인공 수정 후 60일 째 제왕절개를 실시하였다. 8마리의 산자가 안전하게 분만이 되었지만, 모든 산자들에서 심각한 활모양 다리, 구개열, 구순열, 확장된 두부(頭部) 등을 포함한 기형이 관찰되었다.

Keywords

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