Progress in Medical Physics (한국의학물리학회지:의학물리)

Korean Society of Medical Physics (한국의학물리학회)
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The Effect of Breathing Biofeedback on Breathing Reproducibility and Patient's Dose in Respiration-gated Radiotherapy

호흡연동 방사선 치료에서 호흡생체자기제어 방식이 호흡 재현성 및 선량에 미치는 영향 평가

  • An, Sohyun (Department of Radiation Oncology, Gachon University Gil Medical Center) ;
  • Yeo, Inhwan (Department of Radiation Medicine, Loma Linda University Medical Center) ;
  • Jung, Jaewon (Department of Physics, East Carolina University) ;
  • Suh, Hyunsuk (Department of Radiation Oncology, School of Medicine, Ewha Womans University) ;
  • Lee, Kyung Ja (Department of Radiation Oncology, School of Medicine, Ewha Womans University) ;
  • Choi, Jinho (Department of Radiation Oncology, Gachon University Gil Medical Center) ;
  • Lee, Kyu Chan (Department of Radiation Oncology, Gachon University Gil Medical Center) ;
  • Lee, Rena (Department of Radiation Oncology, School of Medicine, Ewha Womans University)
  • 안소현 (가천대학교 길병원 방사선종양학과) ;
  • 여인환 ;
  • 정재원 ;
  • 서현숙 (이화여자대학교 의과대학 방사선종양학교실) ;
  • 이경자 (이화여자대학교 의과대학 방사선종양학교실) ;
  • 최진호 (가천대학교 길병원 방사선종양학과) ;
  • 이규찬 (가천대학교 길병원 방사선종양학과) ;
  • 이레나 (이화여자대학교 의과대학 방사선종양학교실)
  • Received : 2012.09.27
  • Accepted : 2013.09.02
  • Published : 2013.09.30
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Abstract

We evaluated the effect of two kinds of breathing biofeedback technique such as audio-instruction and audio-visual biofeedback on breathing reproducibility and the CTV coverage during repeated treatment regimes in respiration-gated radiotherapy. In this study, the breathing data of nineteen lung cancer patients acquired from Medical College of Virginia (MCV) during five weeks were used. The dose evaluation algorithm was programmed in MATLAB. In the result, the CTV coverage was decreased as 30.0% due to the breathing irreproducibility for free-breathing. For audio-visual biofeedback, the CTV coverage was improved as 20.0% because patients can learn how control their breathing stably. And the audio-instruction was effective to preserve the breathing reproducibility.

호흡 연동 방사선 치료 시 사용되는 음성 유도 및 음성-영상 유도의 두 가지 호흡생체자기제어 방식이 호흡 재현성 및 선량에 미치는 영향을 평가하였다. 본 연구에서는 Medical College of Virginia (MCV)에서 획득한 19명의 폐암 환자에 대한 호흡 데이터를 이용하였다. 호흡 데이터는 총 5주간 1주 간격으로 자유 호흡, 음성 유도, 음성-영상 유도의 세 가지 형태로 획득하였으며 선량 평가는 MATLAB을 이용하였다. 그 결과, 자유 호흡의 경우에는 반복되는 치료에서 호흡재현성이 감소하여 CTV 선량이 약 30.0% 감소하는 것을 알 수 있었으며, 음성-영상 유도 방식을 이용할 경우 5주 후 CTV 선량이 20.0% 개선됨을 알 수 있었다. 이는 환자가 영상을 통하여 자가호흡조절 능력이 향상되기 때문으로 판단된다. 또한 음성 유도만 사용할 경우에도 호흡재현성을 유지하는 데는 효과적임을 확인하였다.

Keywords

References

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