Poor Fibrinolytic Response on a Single Bout Exercise Intensity and Time in Male Chronic Ischemic Stroke Patient

남성 만성기 허혈성 뇌졸중환자의 운동강도 및 시간에 대한 Poor Fibrinolytic Response

  • Kang, Dong-Yeon (Department of Rehabilitation Science, Graduate School, Daegu University) ;
  • Lee, Hye-Young (Department of Rehabilitation Science, Graduate School, Daegu University) ;
  • Kim, Kyoung (Department of Physical Therapy, College of Rehabilitation Science, Daegu University)
  • 강동연 (대구대학교 대학원 재활과학과) ;
  • 이혜영 (대구대학교 대학원 재활과학과) ;
  • 김경 (대구대학교 재활과학대학 물리치료학과)
  • Received : 2013.07.15
  • Accepted : 2013.08.15
  • Published : 2013.08.25

Abstract

Purpose: The purpose of this case study was to investigate three poor fibrinolytic responders with chronic ischemic stroke to acute exercise intensity and time. Methods: Three ischemic stroke patients (male) from the stroke center located at Busan metropolitan area in Republic of Korea volunteered at this study. They performed two single session exercises that were a VO2peak test and a single bout treadmill walking (70-75%HRpeak, 30 min, 50min). Fasting blood samples for determination of tissue Plasminogen Activator (tPA) and Plasminogen Activator Inhibitor-1 (PAI-1) were obtained before, immediately after, 30min after acute exercise. SPSS 12.0 was used for analyzing of data and computing mean and standard deviation, and change rate was conducted between times. Results: In fibrinolytic activity according to the intensity and time of acute exercise, tPA change increased steadily during the recovery stage after the VO2peak in the cases, but PAI-1 activity showed different patterns among the cases. In a single bout treadmill walking (70-75%HRpeak, 30 min, 50min), tPA change increased between 30min and 50min. Conclusion: In conclusion, these results suggest that the exercise prescription for poor fibrinolytic responder with three male chronic ischemic stroke patients without motor disability recommend at 70-75%HRpeak, over 30min.

Keywords

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