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Current Research Trend on Acupuncture Treatment for Nerve Regeneration and Recovery: Based on the Data of PubMed

침 치료가 신경 재생 및 회복에 미치는 영향에 대한 연구 동향: PubMed를 중심으로

  • Yang, Mi-Sung (Department of Oriental Rehabilitation Medicine, Dongshin University Oriental Medicine) ;
  • Kim, Sun-Jong (Department of Oriental Rehabilitation Medicine, Dongshin University Oriental Medicine) ;
  • Choi, Jin-Bong (Department of Oriental Rehabilitation Medicine, Dongshin University Oriental Medicine)
  • 양미성 (동신대학교 한의과대학 한방재활의학과) ;
  • 김선종 (동신대학교 한의과대학 한방재활의학과) ;
  • 최진봉 (동신대학교 한의과대학 한방재활의학과)
  • Received : 2014.11.04
  • Accepted : 2014.11.27
  • Published : 2014.12.27

Abstract

Objectives : The purpose of this study is to explore the current research trend on acupuncture treatment for nerve regeneration and recovery effect. Methods : We investigated the researches so far, on acupuncture treatment for the nerve regeneration and recovery via searching Pubmed from 2005 up to October 2014. Data were extracted from the included studies regarding the authors, countries, type of nerve injury, type of acupuncture, treatment period, acupuncture points, assessment tool and results. Results and Conclusions : Twenty-four research papers were included in the review. Outcomes were measured by immunohistochemical results, motor behavior scores, and electrocphysiological results. All but one study favored acupuncture and electroacupuncture treatment for nerve regeneration and recovery regardless of type of nerve injury and acupuncture modality. Acupuncture treatment may have a potential for nerve regeneration and recovery and further research is required.

Keywords

References

  1. Cho MS, Lee HS, Kim MH. Application of Human Embryonic Stem Cells for Neural Disease. Tissue Engineering and Regenerative medicine. 2007 ; 4(2) : 159-62.
  2. Barnett HJ, Eliasziw M, Meldrum HE. Evidence based cardiology: prevention of ischemic stroke. BMJ. 1999 ; 318(7197) : 1539-43. https://doi.org/10.1136/bmj.318.7197.1539
  3. Korea Geriatrics Society. Geriatrics Medicine. Seoul: Medical Publisher. 2002 : 67-71.
  4. Kim DA, Lee BS, Kim EJ, Choi H. Epidemiological analysis of the spinal cord disabilities 16 years admitted to the National Rehabilitation Center. Research report about Quality of life in Korea spinal cord disabilities. National Rehabilitation Center 2012.
  5. Ide C. Peripheral nerve regeneration. Neuroscience res. 1996 ; 25 : 101-21. https://doi.org/10.1016/0168-0102(96)01042-5
  6. TJ Coderre, J Katz, AL Vaccarino, R Melzack. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain, 1993 ; 52(3) : 259-85. https://doi.org/10.1016/0304-3959(93)90161-H
  7. Shin SL, Kim AL. Factors Effect on Quality of Life of Spinal Cord Injury Patients. Journal of Nurses Academic Society. 2001 ; 31(1) : 126-38. https://doi.org/10.4040/jkan.2001.31.1.126
  8. DeLisa JA. Developing an intergrative approach to spinal cord medicine. J spinal cord Med. 2003 ; 26(1) : 27. https://doi.org/10.1080/10790268.2003.11753656
  9. Lee KH, Yoon DH, Park YG, Lee BH. Effects of glial transplantation on functional recovery following acute spinal cord injury. J Neurotrauma. 2005 ; 22(5) : 575-89. https://doi.org/10.1089/neu.2005.22.575
  10. Yang MS, Kee YB, Kang DH, Shin MS , Kim SJ, Choi JB. The Effects of ST36, GB34, GB39 and Hyeopcheok Points on Nerve Regeneration in Spinal Cord Injury Rat Model. J Oriental Rehab Med. 2012 ; 22(4) : 1-21.
  11. Ahn HL ,Yang MS, Shin MS, Choi JB, Kim SJ. The Experimental Study of Electroacupuncture and CerviPantortichum Cornu Pharmacopuncture on Pain Decrease and Nerve Regeneration after Crush Injury of Sciatic NerveJ Oriental Rehab Med. 2009 ; 19(1) : 39-55.
  12. Sul JU, Chu MK, Kim SJ, Choi JB, Shin MS, Kim Soo-Ik. Effects of Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang) and Electrical Acupuncture on the Spinal Nerve Injury and the Motor Function. J Oriental Rehab Med. 2009 ; 19(2) : 1-25.
  13. Wang JS, Park JH, Moon OK, Kim NJ, Choi JH, Kim JS. The Effect of Needle Electrode Electrical Stimulation Following Global Ischemia on the Suppression of Apoptosis in the Cerebellum. JKIECS. 2013 ; 12(8) : 1949-58. https://doi.org/10.13067/JKIECS.2013.8.11.1949
  14. Choi JH, Min KO, Kim SH, Kim DI, Lee SB, An HJ, et al. A Study on the Effects of the Electro-Acupuncture(EA) Stimulation after Global Ischemia(GI) on Changes in Bax and Caspase-3 Expression among Forebrain Apoptosis. J. of Oriental Neuropsychiatry 2010 ; 21(1) : 59-69.
  15. Zhou H, Sun G, Kong L, Du Y, Shen F, Wang S, et al. Acupuncture and moxibustion reduces neuronal edema in Alzheimer's disease rats. Neural Regen Res. 2014 ; 9(9) : 968-72. https://doi.org/10.4103/1673-5374.133148
  16. Zhang R, Cai X, Song X, Dong C, Hou X, Lv L. Normalization of ventral tegmental area structure following acupuncture in a rat model of heroin relapse. Neural Regen Res. 2014 ; 9(3) : 301-7. https://doi.org/10.4103/1673-5374.128228
  17. Hou X, Zhang R, Lv H, Cai X, Xie G, Song X. Acupuncture at Baihui and Dazhui reduces brain cell apoptosis in heroin readdicts. Neural Regen Res. 2014 ; 9(2) : 164-70. https://doi.org/10.4103/1673-5374.125345
  18. Wang SJ, Fang JQ, Ma J, Wang YC, Liang SR, Zhou D, et al. Electroacupuncture-regulated neurotrophic factor mRNA expression in the substantia nigra of Parkinson's disease rats. Neural Regen Res. 2013 ; 8(6) : 540-9.
  19. Huang SF, Ding Y, Ruan JW, Zhang W, Wu JL, He B, et al. An experimental electro-acupuncture study in treatment of the rat demyelinated spinal cord injury induced by ethidium bromide. Neurosci Res. 2011 ; 70(3) : 294-304. https://doi.org/10.1016/j.neures.2011.03.010
  20. Li WJ, Pan SQ, Zeng YS, Su BG, Li SM, Ding Y, et al. Identification of acupuncture-specific proteins in the process of electro- acupuncture after spinal cord injury. Neurosci Res. 2010 ; 67(4) : 307-16. https://doi.org/10.1016/j.neures.2010.04.012
  21. Chen J, Qi JG, Zhang W, Zhou X, Meng QS, Zhang WM, et al. Electro-acupuncture induced NGF, BDNF and NT-3 expression in spared L6 dorsal root ganglion in cats subjected to removal of adjacent ganglia. Neurosci Res. 2007 ; 59(4) : 399-405. https://doi.org/10.1016/j.neures.2007.08.006
  22. Sun YJ, Wu YC, Zhang JF, Zhang P, Tang ZY. Effects of electroacupuncture on muscle state and electrophysiological changes in rabbits with lumbar nerve root compression. Chin J Integr Med. 2013 ; 19(6) : 446-52. https://doi.org/10.1007/s11655-013-1340-3
  23. Liu ZH, Qi YC, Pan PG, Ma MM, Qian XG, Fu WJ. Clinical observation on treatment of clearing the Governor Vessel and refreshing the mind needling in neural development and remediation of children with cerebral palsy. Chin J Integrative Medicine. 2013 ; 19(7) : 505-9. https://doi.org/10.1007/s11655-013-1504-9
  24. Inoue M, Katsumi Y, Itoi M, Hojo T, Nakajima M, Ohashi S, et al. Direct current electrical stimulation of acupuncture needles for peripheral nerve regeneration: an exploratory case series. Acupunct Med. 2011 ; 29(2) : 88-93. https://doi.org/10.1136/aim.2010.003046
  25. Kim MW, Chung YC, Jung HC, Park MS, Han YM, Chung YA, et al. Electroacupuncture enhances motor recovery performance with brain-derived neurotrophic factor expression in rats with cerebral infarction. Acupunct Med. 2012 ; 30(3) : 222-6. https://doi.org/10.1136/acupmed-2011-010126
  26. Kim WS, Kim IS, Kim SJ, Wei PF, Choi DH, Han TR. Effect of electroacupuncture on motor recovery in a rat stroke model during the early recovery stage. Brain Research. 2009 ; 1248 : 176-83. https://doi.org/10.1016/j.brainres.2008.11.009
  27. Pagani L, Manni L, Aloe L. Effects of electroacupuncture on retinal nerve growth factor and brain-derived neurotrophic factor expression in a rat model of retinitis pigmentosa. Brain Res. 2006 ; 1092(1) : 198-206. https://doi.org/10.1016/j.brainres.2006.03.074
  28. Choi DC, Lee JY, Moon YJ, Kim SW, Oh TH, Yune TY. Acupuncture- mediated inhibition of inflammation facilitates significant functional recovery after spinal cord injury. Neurobiol Dis. 2010 ; 39(3) : 272-82. https://doi.org/10.1016/j.nbd.2010.04.003
  29. Kim YR, Kim HN, Ahn SM, Choi YH, Shin HK, Choi BT. Electroacupuncture promotes post-stroke functional recovery via enhancing endogenous neurogenesis in mouse focal cerebral ischemia. PLoS One. 2014 ; 9(2) : e90000. https://doi.org/10.1371/journal.pone.0090000
  30. Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zeng X, et al. Bone marrow mesenchymal stem cells and electroacupuncture downregulate the inhibitor molecules and promote the axonal regeneration in the transected spinal cord of rats. Cell Transplant. 2011 ; 20(4) : 475-91. https://doi.org/10.3727/096368910X528102
  31. Yan Q, Ruan JW, Ding Y, Li WJ, Li Y, Zeng YS. Electro-acupuncture promotes differentiation of mesenchymal stem cells, regeneration of nerve fibers and partial functional recovery after spinal cord injury. Exp Toxicol Pathol. 2011 ; 63(1-2) : 151-6. https://doi.org/10.1016/j.etp.2009.11.002
  32. Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zhang YJ, et al. Electro-acupuncture promotes survival, differentiation of the bone marrow mesenchymal stem cells as well as functional recovery in the spinal cord-transected rats. BMC Neurosci. 2009 ; 20 ; 10 : 35. https://doi.org/10.1186/1471-2202-10-35
  33. Li WJ, Li SM, Ding Y, He B, Keegan J, et al. Electro-acupuncture upregulates CGRP expression after rat spinal cord transection. Neurochem Int. 2012 ; 61(8) : 1397-403. https://doi.org/10.1016/j.neuint.2012.10.002
  34. Wang TT, Yuan Y, Kang Y, Yuan WL, Zhang HT, Wu LY, et al. Effects of acupuncture on the expression of glial cell line-derived neurotrophic factor(GDNF) and basic fibroblast growth factor(FGF-2/bFGF) in the left sixth lumbar dorsal root ganglion following removal of adjacent dorsal root ganglia. Neurosci Lett. 2005 ; 382(3) : 236-41. https://doi.org/10.1016/j.neulet.2005.03.020
  35. Wang TH, Wang XY, Li XL, Chen HM, Wu LF. Effect of electroacupuncture on neurotrophin expression in cat spinal cord after partial dorsal rhizotomy. Neurochem Res. 2007 ; 32(8) : 1415-22. https://doi.org/10.1007/s11064-007-9326-9
  36. La JL, Jalali S, Shami SA. Morphological studies on crushed sciatic nerve of rabbits with electroacupuncture or diclofenac sodium treatment. Am J Chin Med. 2005 ; 33(4) : 663-9. https://doi.org/10.1142/S0192415X05003259
  37. Ho CY, Yao CH, Chen WC, Shen WC, Bau DT. Electroacupuncture and Acupuncture Promote the Rat's Transected Median Nerve Regeneration. Evid Based Complement Alternat Med. 2013 ; 2013 : 514610.
  38. Schröder S, Liepert J, Remppis A, Greten JH. Acupuncture treatment improves nerve conduction in peripheral neuropathy. Eur J Neurol. 2007 ; 14(3) : 276-81.
  39. Manni L, Albanesi M, Guaragna M, Barbaro Paparo S, Aloe L. Neurotrophins and acupunctures. Auton Neurosci. 2010 ; 157(1-2) : 9-17. https://doi.org/10.1016/j.autneu.2010.03.020

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