Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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The Effects of Sterilization on Jakyakgamcho Decoction(Shaoyaogancao Decoction) Pharmacopuncture: an Investigation to Minimize Loss of Principal Components

멸균에 따른 작약감초약침의 지표 성분변화 및 해결방안

  • Lee, Jong Hwan (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Jun, Jae Yun (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Lim, Su Jin (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Kim, Hae Sol (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Kim, Ho Sun (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Bae, Young Hyeon (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Lee, In Hee (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Kim, Min Jeong (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Kim, Eun Jee (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Ha, In Hyuk (Department of Rehabilitation Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Lee, Jin Ho (Department of Rehabilitation Medicine, Gang-Nam Jaseng Oriental Medicine Hospital) ;
  • Lee, Jae Woong (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital)
  • 이종환 (자생한방병원 침구의학과) ;
  • 전재윤 (자생한방병원 침구의학과) ;
  • 임수진 (자생한방병원 침구의학과) ;
  • 김해솔 (자생한방병원 침구의학과) ;
  • 김호선 (자생한방병원 침구의학과) ;
  • 배영현 (자생한방병원 침구의학과) ;
  • 이인희 (자생한방병원 R&D센터) ;
  • 김민정 (자생한방병원 R&D센터) ;
  • 김은지 (자생한방병원 R&D센터) ;
  • 하인혁 (자생한방병원 재활의학과) ;
  • 이진호 (자생한방병원 재활의학과) ;
  • 이재웅 (자생한방병원 R&D센터)
  • Received : 2014.11.04
  • Accepted : 2014.11.26
  • Published : 2014.12.20
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Abstract

Objectives : Jakyakgamcho decoction is a traditional prescription known to be an effective pain control medication and muscle relaxant. For more localized treatment outcomes achieved in a shorter period of time, Jakyakgamcho decoction was reprocessed into a form of pharmacopuncture. An analysis of Jakyakgamcho decoction pharmacopuncture showed that there was a significant loss of paeoniflorin(Jakyak's index component). This study was designed to investigate ways to minimize this loss. Methods : After making changes to the processing methods of Jakyakgamcho decoction pharmacopuncture, we measured the quantity of paeoniflorin using high performance liquid chromatography(HPLC) for a before-and-after analysis Results : Paeoniflorin loss was observed 15 minutes after sterilization with $Na_2HPO_4$ at $121^{\circ}C$ Conclusions : It was found that paeoniflorin loss did not occur when pH was not controlled for during processing.

Keywords

References

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