The Journal of Advanced Prosthodontics

  • 제6권6호
  • /
  • Pages.555-558
  • /
  • 2014
  • /
  • 2005-7806(pISSN)
  • /
  • 2005-7814(eISSN)
대한치과보철학회 (The Korean Academy of Prosthodonitics)
권호 표지
DOI QR코드

DOI QR Code

Focal epithelial hyperplasia arising after delivery of metal-ceramic fixed dental prosthesis

  • Park, Min-Woo (Department of Oral and Maxillofacial Surgery, Dental Reaserch Institute, Seoul National University) ;
  • Cho, Young-Ah (Department of Oral and Maxillofacial Pathology, School of Dentistry, Kyung Hee University) ;
  • Kim, Soung-Min (Department of Oral and Maxillofacial Surgery, Dental Reaserch Institute, Seoul National University) ;
  • Myoung, Hoon (Department of Oral and Maxillofacial Surgery, Dental Reaserch Institute, Seoul National University) ;
  • Lee, Jong-Ho (Department of Oral and Maxillofacial Surgery, Dental Reaserch Institute, Seoul National University) ;
  • Lee, Suk-Keun (Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University)
  • 투고 : 2014.05.20
  • 심사 : 2014.11.07
  • 발행 : 2014.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Focal epithelial hyperplasia (FEH) is a human papillomavirus (HPV)-induced alteration of the oral mucosa that presents with a clinically distinct appearance. While other HPV-infected lesions such as squamous papilloma, verruca vulgaris, and condyloma acuminatum involve the skin, oral mucosa, and genital mucosa, FEH occurs only in the oral mucosa. The affected oral mucosa exhibits multiple papules and nodules with each papule/nodule being flat-topped or sessile. The affected region resembles the normal color of oral mucosa rather than appearing as a white color since the epithelial surface is not hyperkeratinized. Almost all cases present with multiple sites of occurrence. This rare, benign epithelial proliferation is related to low-risk HPV, especially HPV-13 and -32, and is not transformed into carcinoma. We report a case of FEH that arose on the attached gingiva of an East Asian male adult related to prosthesis without detection of any HPV subtype in HPV DNA chip and sequencing.

키워드

참고문헌

  1. Archard HO, Heck JW, Stanley HR. Focal epithelial hyperplasia: an unusual oral mucosal lesion found in indian children. Oral Surg Oral Med Oral Pathol 1965;20:201-12. https://doi.org/10.1016/0030-4220(65)90192-1
  2. Said AK, Leao JC, Fedele S, Porter SR. Focal epithelial hyperplasia - an update. J Oral Pathol Med 2013;42:435-42. https://doi.org/10.1111/jop.12009
  3. Jayasooriya PR, Abeyratne S, Ranasinghe AW, Tilakaratne WM. Focal epithelial hyperplasia (Heck's disease): report of two cases with PCR detection of human papillomavirus DNA. Oral Dis 2004;10:240-3. https://doi.org/10.1111/j.1601-0825.2004.01012.x
  4. Maschke J, Brauns TC, Goos M. Imiquimod for the topical treatment of focal epithelial hyperplasia (Heck disease) in a child. J Dtsch Dermatol Ges 2004;2:848-50. https://doi.org/10.1046/j.1439-0353.2004.04751.x
  5. Kim SM, Myoung H, Choung PH, Kim MJ, Lee SK, Lee JH. Metastatic leiomyosarcoma in the oral cavity: case report with protein expression profiles. J Craniomaxillofac Surg 2009;37:454-60. https://doi.org/10.1016/j.jcms.2009.06.010
  6. Bennett LK, Hinshaw M. Heck's disease: diagnosis and susceptibility. Pediatr Dermatol 2009;26:87-9. https://doi.org/10.1111/j.1525-1470.2008.00830.x
  7. AlSheddi MA, Faden AA. Multifocal epithelial hyperplasia in an adult female. Hong Kong J Dermatol Venereol 2012;20:23-7.
  8. Padayachee A, van Wyk CW. Human papillomavirus (HPV) DNA in focal epithelial hyperplasia by in situ hybridization. J Oral Pathol Med 1991;20:210-4. https://doi.org/10.1111/j.1600-0714.1991.tb00420.x
  9. Ledesma-Montes C, Vega-Memije E, Garces-Ortiz M, Cardiel-Nieves M, Juarez-Luna C. Multifocal epithelial hyperplasia. Report of nine cases. Med Oral Patol Oral Cir Bucal 2005;10:394-401.
  10. Pfister H, Hettich I, Runne U, Gissmann L, Chilf GN. Characterization of human papillomavirus type 13 from focal epithelial hyperplasia Heck lesions. J Virol 1983;47:363-6.
  11. Beaudenon S, Praetorius F, Kremsdorf D, Lutzner M, Worsaae N, Pehau-Arnaudet G, Orth G. A new type of human papillomavirus associated with oral focal epithelial hyperplasia. J Invest Dermatol 1987;88:130-5. https://doi.org/10.1111/1523-1747.ep12525278
  12. Burd EM. Human papillomavirus and cervical cancer. Clin Microbiol Rev 2003;16:1-17. https://doi.org/10.1128/CMR.16.1.1-17.2003
  13. Falaki F, Amir Chaghmaghi M, Pakfetrat A, Delavarian Z, Mozaffari PM, Pazooki N. Detection of human papilloma virus DNA in seven cases of focal epithelial hyperplasia in Iran. J Oral Pathol Med 2009;38:773-6. https://doi.org/10.1111/j.1600-0714.2009.00784.x
  14. Ozden B, Gunduz K, Gunhan O, Ozden FO. A Case Report of Focal Epithelial Hyperplasia (Heck's disease) with PCR Detection of Human Papillomavirus. J Maxillofac Oral Surg 2011;10:357-60. https://doi.org/10.1007/s12663-011-0184-2
  15. Choi YD, Jung WW, Nam JH, Choi HS, Park CS. Detection of HPV genotypes in cervical lesions by the HPV DNA Chip and sequencing. Gynecol Oncol 2005;98:369-75. https://doi.org/10.1016/j.ygyno.2005.04.044
  16. Ledesma-Montes C, Garces-ortiz M, Edmundo B. Multifocal epithelial hyperplasia. An unusual lesion. Webmedcentral Pathology 2012;3:WMC003003.
  17. Ciszewski A, Baraniak M, Urbanek-Brychczynska M. Corrosion by galvanic coupling between amalgam and different chromium-based alloys. Dent Mater 2007;23:1256-61. https://doi.org/10.1016/j.dental.2006.11.006
  18. Padbury A Jr, Eber R, Wang HL. Interactions between the gingiva and the margin of restorations. J Clin Periodontol 2003;30:379-85. https://doi.org/10.1034/j.1600-051X.2003.01277.x

피인용 문헌

  1. Human papilloma virus in oral cancer vol.42, pp.6, 2016, https://doi.org/10.5125/jkaoms.2016.42.6.327
  2. Focal Epithelial Hyperplasia (Heck’s Disease) in a 57-Year-Old Brazilian Patient: A Case Report and Literature Review vol.8, pp.4, 2014, https://doi.org/10.14740/jocmr2466w