Journal of Korean society of Dental Hygiene (한국치위생학회지)

Korean Society of Dental Hygiene (한국치위생학회)
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Antimicrobial activity of Prunus mume extract to oral microbes

매실추출물(PME)의 구강 미생물에 대한 항균작용

  • Jang, Jong-Hwa (Department of Dental Hygiene, a Graduate School, Hanseo University) ;
  • Kim, Young-In (Department of Dental Hygiene, a Graduate School, Hanseo University) ;
  • Lee, Hyun (Department of Laboratory Medicine, Seoul National University Hospital)
  • 장종화 (한서대학교대학원 치위생학과) ;
  • 김영인 (한서대학교대학원 치위생학과) ;
  • 이현 (서울대학교병원 진단검사의학과)
  • Received : 2013.12.22
  • Accepted : 2014.02.12
  • Published : 2014.02.28
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Abstract

Objectives : Prunus mume has been used for the folk medicine from old times. The purpose of the study was to investigate the antimicrobial activity of prunus mume extract to various oral microbes. Methods : This study was carried out to examine the antimicrobial effect of Prunus mume extract against oral microbes. Data were collected using a Dentocult SM Strip mutans and Dentocult LB Strip mutans from April 5 to May 4, 2013. A total of 36 experimental and 32 control group were selected for this study. Results : The MIC of Prunus mume extract was tested for 0.39% in S. mutans, S. salivarius and S. auerus, 0.78% in S. mitis, S. equi and E. coli. In vivo, experimental group showed significantly the lower Streptococcus mutans levels by the use of the gum contained Prunus mume extract from 15 days compared with control group(p=0.012). The reduction was more significant in Lactobacilli level of the experimental group than the control group(p=0.022). Conclusions : These findings suggest that the oral products containing Prunus mume extracts is effective in preventing oral diseases.

Keywords

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