Analysis of Clinical Researches on Traditional Medicine Treatment for Behcet's Disease in Korea, China, and Japan

한중일의 베체트병에 대한 한의약 임상연구 분석

  • Yong, Seokil (School of Korean Medicine, Pusan National University) ;
  • Gu, Hyungyung (School of Korean Medicine, Pusan National University) ;
  • Kim, Daehun (Department of Acupuncture & Moxibustion Medicine, Pusan National University Korean Medicine Hospital) ;
  • Sohn, Kyungwoo (Department of Oriental Internal Medicine, Samse Oriental Medicine Hospital) ;
  • Yun, Youngju (Department of Integrative Medicine, School of Korean Medicine, Pusan National University)
  • 용석일 (부산대학교 한의학전문대학원 한의학과) ;
  • 구현경 (부산대학교 한의학전문대학원 한의학과) ;
  • 김대훈 (부산대학교 한방병원 침구의학과) ;
  • 손경우 (삼세한방병원 한방내과) ;
  • 윤영주 (부산대학교 한의학전문대학원 동서협진의학)
  • Received : 2014.03.31
  • Accepted : 2014.04.25
  • Published : 2014.04.30

Abstract

Objective : To find a treatment strategy, this study aimed to review and compare the clinical studies of Korea, China, and Japan on traditional medicine treatment for Behcet's disease. Method : Literature searches were performed on six databases in each country and English databases, such as OASIS, KoreanTK, CNKI, J-STAGE, PubMed, and Cochrane CENTRAL. In addition, using the limited keywords, the area was restricted to traditional medicine treatment, but the period was not limited. Studies were categorized according to the study design and we analyzed the difference of treatment among three countries. Results : One hundred and forty-one clinical studies met our inclusion criteria: 11 studies in Korea, 15 in Japan, 115 in China. Randomized controlled trials (RCT) have increased in China, however, no RCT was reported in Korea and Japan. The method of treatment was mainly traditional herbal medicine in all the three countries, but there were significant differences in the field of syndrome identification and prescription among countries. The studies in China made use of most various treatment modalities and reported the highest effectiveness. Conclusion : Traditional medicine treatment showed a considerable effect for improving various symptoms of Behcet's disease. However, more research for answering the safety and well-designed studies considering characteristics of Behcet's disease should be performed to evaluate the effectiveness of traditional medicine treatment objectively in the future.

Keywords

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