Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Profile of Colorectal Polyps: a Retrospective Study from King Fahad Hospital, Madinah, Saudi Arabia

  • Published : 2014.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

Aim: To evaluate the predominant colorectal polyps in the Almadinah region of Saudi Arabia. Materials and Methods: In this iretrospective study, we analyzed pathology reports of colonoscopies performed in King Fahad Hospital, Madinah, Saudi Arabia during the period 2006 to 2013. Data based on patient age, gender, size, site and type of polyps and the degree of dysplasia were analyzed by software SPSS 17 and compared with other published studies from different geographic regions of the world. Results: During these years, 224 patients had colonic polyps, of whom 149 (66.5%) were men and 75 (33.5%) were women. The most common types of polyps were adenomatous (166), followed by hyperplastic polyps (24), juvenile (18), inflammatory (13), lipomatous (2) and one patient with Peutz-Jegher polyps. Tubulovillous adenoma was the commonest adenomatous polyp (102), followed by tubular (41) and villous (23) types. The sigmoid colon was the most commonly involved region (36.6%). Dysplasia was significantly associated with female patients who had large size tubulovillous polyps located in the left colon. Conclusions: The type and distribution of colorectal polyps in Saudi Arabia is very similar to Western countries. Patient gender, and size, histological type and location of polyps are closely related to dysplastic change in colonic polyps.

Keywords

References

  1. Adelstein BA, Macaskill P, Turner RM, Katelaris PH, Irwig L (2011). The value of age and medical history for predicting colorectal cancer and adenomas in people referred for colonoscopy. BMC Gastroenterol, 11, 97. https://doi.org/10.1186/1471-230X-11-97
  2. Al-Enezi SA, Alsurayei SA, Ismail AE, et al (2010). Adenomatous colorectal polyps in patients referred for colonoscopy in a regional hospital in Kuwait. Saudi J Gastroenterol, 16, 188-93. https://doi.org/10.4103/1319-3767.65194
  3. Al-Rashed RS, Al-Amri SM (1996). Colonic polyps: Experience from King Khalid University Hospital. Ann Saudi Med, 16, 180-3.
  4. American Cancer Society. Colorectal Cancer Facts & Figures 2011-2013. Atlanta: American Cancer Society, 2011 (PDF Accessed - 02/02/2014).
  5. Bafandeh Y, Daghestani D, Esmaili H (2005). Demographic and anatomical survey of colorectal polyps in an Iranian population. Asian Pac J Cancer Prev, 6, 537-40.
  6. Bafandeh Y, Khoshbaten M, Eftekhar Sadat AT, Farhang S (2008). Clinical predictors of colorectal polyps and carcinoma in a low prevalence region: results of a colonoscopy based study. World J Gastroenterol, 14, 1534-8. https://doi.org/10.3748/wjg.14.1534
  7. Bashir S, Nadeem R, Khan NR, Suleman BS, Qureshi GR (2012). Histopathological Analysis of 1000 Colorectal Biopsies in Two Years in Shaikh Zayed Hospital, Lahore. Pak J Med Health Sci, 6, 115-7.
  8. Bokhary R (2009). Serrated Colonic Polyps in a Teaching Hospital in Saudi Arabia: Prevalence and Review of Classification. Saudi J Gastroenterol, 15, 234-8. https://doi.org/10.4103/1319-3767.56097
  9. Brooks DD, Winawer SJ, Rex DK, et al (2008). Colonoscopy surveillance after polypectomy and colorectal cancer resection. Am Fam Physician, 77, 995-1002.
  10. Cancer Incidence Report.Saudi Arabia 2009 (2012). Kingdom of Saudi Arabia Ministry of Health Saudi Cancer Registry. Issued Dec 2012.(www.scr.org.sa accessed 19/01/2014).
  11. Consolo P, Luigiano C, Pellicano R, et al (2010). Endoscopic resection as a safe and effective technique for treatment of pedunculated and non-pedunculated benign-appearing colorectal neoplasms measuring 40 mm or more in size. Minerva Med, 101, 311-8.
  12. Eshghi MJ, Fatemi R, Hashemy A, Aldulaimi D, MahsaKhodadoostan (2011). A retrospective study of patients with colorectal polyps. Gastroenterology and Hepatology From Bed to Bench, 4, 17-22.
  13. Ferlitsch M, Reinhart K, Pramhas S, et al (2011). Sex-specific prevalence of adenomas, advanced adenomas, and colorectal cancer in individuals undergoing screening colonoscopy. JAMA, 306, 1352-8. https://doi.org/10.1001/jama.2011.1362
  14. Geramizadeh B, Keshtkar-Jahromi M (2013). Pathology of colorectal polyps: a study from South of Iran. Ann Colorectal Res, 1, 59-61.
  15. Giacosa A, Frascio F, Munizzi F (2004). Epidemiology of colorectal polyps. Tech Coloproctol, 8, 243-7. https://doi.org/10.1007/s10151-004-0169-y
  16. Goh KL, Quek KF, Yeo GT, et al (2005). Colorectal cancer in Asians: a demographic and anatomic survey in Malaysian patients undergoing colonoscopy. Aliment Pharmacol Ther, 22, 859-64. https://doi.org/10.1111/j.1365-2036.2005.02646.x
  17. Health Quality Ontario (2009). Screening methods for early detection of colorectal cancers and polyps: summary of evidence-based analyses. Summary of Evidence-Based Analyses. Ont Health Technol Assess Ser, 9, 1-65.
  18. Heitman SJ, Ronksley PE, Hilsden RJ, et al (2009). Prevalence of adenomas and colorectal cancer in average risk individuals: a systematic review and meta-analysis. Clin Gastroenterol Hepatol, 7, 1272-8. https://doi.org/10.1016/j.cgh.2009.05.032
  19. Hwang H (2013). Colorectal cancer screening among Asian Americans. Asian Pac J Cancer Prev, 14, 4025-32. https://doi.org/10.7314/APJCP.2013.14.7.4025
  20. Ibrahim EM, Zeeneldin AA, El-Khodary TR, Al-Gahmi AM, Bin Sadiq BM (2008). Past, present and future of colorectal cancer in the Kingdom of Saudi Arabia. Saudi J Gastroenterol, 14, 178-82. https://doi.org/10.4103/1319-3767.43275
  21. Jemal A, Siegel R, Xu J, Ward E (2010). Cancer statistics, 2010. CA Cancer J Clin, 60, 277-300. https://doi.org/10.3322/caac.20073
  22. Jemal A, Center MM, DeSantis C, Ward EM(2010). Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiol Biomarkers Prev, 19, 1893-907. https://doi.org/10.1158/1055-9965.EPI-10-0437
  23. Lam TJ, Wong BC, Mulder CJ, et al (2007). Increasing prevalence of advanced colonic polyps in young patients undergoing colonoscopy in a referral academic hospital in Hong Kong.World J Gastroenterol, 13, 3873-7.
  24. Lee B, Holub J, Peters D, Lieberman D (2012). Prevalence of colon polyps detected by colonoscopy screening of asymptomatic Hispanic Patients. Dig Dis Sci, 57, 481-8. https://doi.org/10.1007/s10620-011-1898-1
  25. Levin B, Lieberman DA, McFarland B, et al (2008): Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin, 58, 130-60. https://doi.org/10.3322/CA.2007.0018
  26. Liu HH, Wu MC, Peng Y, Wu MS (2005). Prevalence of advanced colonic polyps in asymptomatic Chinese. World J Gastroenterol, 11, 4731-4.
  27. Mosli MH, Al-Ahwal MS (2012). Does the increasing trend of colorectal cancer incidence in Jeddah reflect a rise in the Kingdom of Saudi Arabia? Asian Pac J Cancer Prev, 13, 6285-8 . https://doi.org/10.7314/APJCP.2012.13.12.6285
  28. Munteanu M, Serban C, Savoiu G, Popescu A, Sporea I (2009). Clinical, endoscopic and morphological study of colorectal polyps. Ann RSCB, 14, 1-4.
  29. Neri E, Faggioni L, Cini L, Bartolozzi C (2010). Colonic polyps: inheritance, susceptibility, risk evaluation, and diagnostic management. Cancer Manag Res, 3, 17-24.
  30. Onyekwere CA, Odiagah JN, Ogunleye OO, Chibututu C, Lesi OA (2013). Colonoscopy practice in Lagos, Nigeria: a report of an audit. Diagn Ther Endosc, 798651, 1-6.
  31. Patil R, Khoosal S, Cassidy L, Ona M (2013). Characteristics and risk stratification of colon polyps among asymptomatic hispanic patients undergoing first time screening colonoscopy: a retrospective study. J Gastroint Dig Syst, 3, 1-3.
  32. Qayyum A, Sawan AS (2009). Profile of colonic biopsies in King Abdul Aziz University Hospital, Jeddah. J Pak Med Assoc, 59, 608-11.
  33. Rim SH, Seeff L, Ahmed F, King JB, Coughlin SS (2009). Colorectal cancer incidence in the United States, 1999-2004: An Updated Analysis of Data From the National Program of Cancer Registries and the Surveillance, Epidemiology, and End Results Program. Cancer, 115, 1967-76. https://doi.org/10.1002/cncr.24216
  34. Tony J, Harish K, Ramachandran TM, Sunilkumar K, Thomas V (2007). Profile of colonic polyps in a southern Indian population. Indian J Gastroenterol, 26, 127-9.
  35. Unal H, Selcuk H, Gokcan H, et al (2007). Malignancy risk of small polyps and related factors. Dig Dis Sci, 52, 2796-99. https://doi.org/10.1007/s10620-007-9782-8
  36. Veruttipong D, Soliman AS, Gilbert SF, et al (2012). Age distribution, polyps and rectal cancer in the Egyptian population-based cancer registry. World J Gastroenterol, 18, 3997-4003. https://doi.org/10.3748/wjg.v18.i30.3997
  37. Wisedopas N, Thirabanjasak D, Taweevisit M (2005). A retrospective study of colonic polyps in King Chulalongkorn Memorial Hospital. J Med Assoc Thai, 88, 36-41.
  38. Zahir ST, Binesh F, Hashemian Z, Hakimi A (2010). Demographic survey on colorectal polyps in ShahidSadoughi Hospital, Yazd, Iran. Rawal Medical Journal, 35, 31-3.
  39. Zare-Mirzaie A, Abolhasani M, Aryamanesh A (2013). Left sided colorectal adenomatous polyps have more risk for high grade dysplasia. Acta Med Iran, 51, 172-7.

Cited by

  1. Histopathological Profile of Benign Colorectal Diseases in Al-Madinah Region of Saudi Arabia vol.15, pp.18, 2014, https://doi.org/10.7314/APJCP.2014.15.18.7673
  2. Frequency of colonic adenomatous polyps in a tertiary hospital in Mumbai vol.35, pp.4, 2016, https://doi.org/10.1007/s12664-016-0681-9