The korean journal of orthodontics (대한치과교정학회지)

The Korean Association Of Orthodontists (대한치과교정학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of various toothpastes on remineralization of white spot lesions

  • Jo, Su-Yeon (Department of Orthodontics, College of Dentistry, Wonkwang University) ;
  • Chong, Hyun-Jeong (Private Practice) ;
  • Lee, Eon-Hwa (Department of Orthodontics, College of Dentistry, Wonkwang University Dental Hospital) ;
  • Chang, Na-Young (Department of Orthodontics, College of Dentistry, Wonkwang University) ;
  • Chae, Jong-Moon (Department of Orthodontics, College of Dentistry, Wonkwang University Dental Hospital) ;
  • Cho, Jin-Hyoung (Department of Orthodontics, College of Dentistry, Wonkwang University Dental Hospital) ;
  • Kim, Sang-Cheol (Department of Orthodontics, College of Dentistry, Wonkwang University Dental Hospital) ;
  • Kang, Kyung-Hwa (Department of Orthodontics, College of Dentistry, Wonkwang Dental Research Institute, Wonkwang University)
  • Received : 2013.03.18
  • Accepted : 2013.11.15
  • Published : 2014.05.25
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: The purpose of this in vitro study was to examine the effects of fluoridated, casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP)-containing, and functionalized ${\beta}$-tricalcium phosphate (fTCP)-containing toothpastes on remineralization of white spot lesions (WSLs) by using Quantitative light-induced fluorescence (QLF-D) Biluminator$^{TM}$ 2. Methods: Forty-eight premolars, extracted for orthodontic reasons from 12 patients, with artificially induced WSLs were randomly and equally assigned to four treatment groups: fluoride (1,000 ppm), CPP-ACP, fTCP (with sodium fluoride), and control (deionized water) groups. Specimens were treated twice daily for 2 weeks and stored in saliva solution (1:1 mixture of artificial and human stimulated saliva) otherwise. QLF-D Biluminator$^{TM}$ 2 was used to measure changes in fluorescence, indicating alterations in the mineral contents of the WSLs, immediately before and after the 2 weeks of treatment. Results: Fluorescence greatly increased in the fTCP and CPP-ACP groups compared with the fluoride and control groups, which did not show significant differences. Conclusions: fTCP- and CPP-ACP-containing toothpastes seem to be more effective in reducing WSLs than 1,000-ppm fluoride-containing toothpastes.

Keywords

References

  1. Øgaard B. White spot lesions during orthodontic treatment: mechanisms and fluoride preventive aspects. Semin Orthod 2008;14:183-93. https://doi.org/10.1053/j.sodo.2008.03.003
  2. Lundström F, Krasse B. Streptococcus mutans and lactobacilli frequency in orthodontic patients; the effect of chlorhexidine treatments. Eur J Orthod 1987;9:109-16. https://doi.org/10.1093/ejo/9.1.109
  3. Chatterjee R, Kleinberg I. Effect of orthodontic band placement on the chemical composition of human incisor tooth plaque. Arch Oral Biol 1979;24:97-100. https://doi.org/10.1016/0003-9969(79)90056-6
  4. Gorelick L, Geiger AM, Gwinnett AJ. Incidence of white spot formation after bonding and banding. Am J Orthod 1982;81:93-8. https://doi.org/10.1016/0002-9416(82)90032-X
  5. Artun J, Brobakken BO. Prevalence of carious white spots after orthodontic treatment with multibonded appliances. Eur J Orthod 1986;8:229-34. https://doi.org/10.1093/ejo/8.4.229
  6. O'Reilly MM, Featherstone JD. Demineralization and remineralization around orthodontic appliances: an in vivo study. Am J Orthod Dentofacial Orthop 1987;92:33-40. https://doi.org/10.1016/0889-5406(87)90293-9
  7. Geiger AM, Gorelick L, Gwinnett AJ, Griswold PG. The effect of a fluoride program on white spot formation during orthodontic treatment. Am J Orthod Dentofacial Orthop 1988;93:29-37. https://doi.org/10.1016/0889-5406(88)90190-4
  8. Ogaard B. Prevalence of white spot lesions in 19- year-olds: a study on untreated and orthodontically treated persons 5 years after treatment. Am J Orthod Dentofacial Orthop 1989;96:423-7. https://doi.org/10.1016/0889-5406(89)90327-2
  9. Ogaard B, Rølla G, Arends J. Orthodontic appliances and enamel demineralization. Part 1. Lesion development. Am J Orthod Dentofacial Orthop 1988;94:68-73. https://doi.org/10.1016/0889-5406(88)90453-2
  10. Mitchell L. Decalcification during orthodontic treatment with fixed appliances-an overview. Br J Orthod 1992;19:199-205. https://doi.org/10.1179/bjo.19.3.199
  11. Baysan A, Lynch E, Ellwood R, Davies R, Petersson L, Borsboom P. Reversal of primary root caries using dentifrices containing 5,000 and 1,100 ppm fluoride. Caries Res 2001;35:41-6. https://doi.org/10.1159/000047429
  12. Schirrmeister JF, Gebrande JP, Altenburger MJ, Mönting JS, Hellwig E. Effect of dentifrice containing 5000 ppm fluoride on non-cavitated fissure carious lesions in vivo after 2 weeks. Am J Dent 2007;20:212-6.
  13. Artun J, Thylstrup A. Clinical and scanning electron microscopic study of surface changes of incipient caries lesions after debonding. Scand J Dent Res 1986;94:193-201.
  14. Reynolds EC. Remineralization of enamel subsurface lesions by casein phosphopeptide-stabilized calcium phosphate solutions. J Dent Res 1997;76:1587-95. https://doi.org/10.1177/00220345970760091101
  15. Shi XQ, Tranaeus S, Angmar-Månsson B. Comparison of QLF and DIAGNOdent for quantification of smooth surface caries. Caries Res 2001;35:21-6. https://doi.org/10.1159/000047426
  16. Murray JJ, Shaw L. Classification and prevalence of enamel opacities in the human deciduous and permanent dentitions. Arch Oral Biol 1979;24:7-13. https://doi.org/10.1016/0003-9969(79)90168-7
  17. Mizrahi E. Enamel demineralization following orthodontic treatment. Am J Orthod 1982;82:62-7. https://doi.org/10.1016/0002-9416(82)90548-6
  18. Dirks OB. Posteruptive changes in dental enamel. J Dent Res 1966;45:503-11. https://doi.org/10.1177/00220345660450031101
  19. Zachrisson BU, Zachrisson S. Caries incidence and oral hygiene during orthodontic treatment. Scand J Dent Res 1971;79:394-401.
  20. Geiger AM, Gorelick L, Gwinnett AJ, Benson BJ. Reducing white spot lesions in orthodontic populations with fluoride rinsing. Am J Orthod Dentofacial Orthop 1992;101:403-7. https://doi.org/10.1016/0889-5406(92)70112-N
  21. Bröchner A, Christensen C, Kristensen B, Tranæus S, Karlsson L, Sonnesen L, et al. Treatment of post-orthodontic white spot lesions with casein phosphopeptide-stabilised amorphous calcium phosphate. Clin Oral Investig 2011;15:369-73. https://doi.org/10.1007/s00784-010-0401-2
  22. Bhat SS, Hegde SK, Habibullah MA, Bernhardt V. Incipient enamel lesions remineralization using casein phosphopeptide amorphous calcium phosphate cream with and without fluoride: a laser fluorescence study. J Clin Pediatr Dent 2012;36:353-5.
  23. Ogata K, Warita S, Shimazu K, Kawakami T, Aoyagi K, Karibe H. Combined effect of paste containing casein phosphopeptide-amorphous calcium phosphate and fluoride on enamel lesions: an in vitro pH-cycling study. Pediatr Dent 2010;32:433-8.
  24. Karlinsey RL, Mackey AC. Solid-state preparation and dental application of an organically modified calcium phosphate. J Mater Sci 2009;44:346-9. https://doi.org/10.1007/s10853-008-3068-1
  25. Derks A, Katsaros C, Frencken JE, van't Hof MA, Kuijpers-Jagtman AM. Caries-inhibiting effect of preventive measures during orthodontic treatment with fixed appliances. A systematic review. Caries Res 2004;38:413-20. https://doi.org/10.1159/000079621
  26. Silverstone LM. Remineralization and enamel caries: significance of fluoride and effect on crystal diameters. In: Leach SA, Edgar WM, eds. Demineralisation and remineralisation of the teeth. Oxford: IRL Press, 1983. p.185-205.

Cited by

  1. Effects of the addition of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on mechanical properties of luting and lining glass ionomer cement vol.3, pp.7, 2014, https://doi.org/10.1088/2053-1591/3/7/075405
  2. Evaluating Acid Resistance Effect of Fluoride-Releasing Dental Materials Using Quantitative Light-Induced Fluorescence-Digital in Vitro vol.6, pp.4, 2016, https://doi.org/10.4236/ojst.2016.64016
  3. Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial vol.89, pp.3, 2014, https://doi.org/10.2319/051818-371.1
  4. In vitro polarized Raman analysis for the evaluation of the efficacy of CPP-ACP remineralizing mousse in tooth hypomineralization vol.3, pp.None, 2014, https://doi.org/10.1016/j.rechem.2021.100232
  5. Hydroxyapatite in Oral Care Products-A Review vol.14, pp.17, 2014, https://doi.org/10.3390/ma14174865
  6. Fluorides-foundation for healthy teeth: a dental perspectives vol.100, pp.3, 2014, https://doi.org/10.1007/s10971-021-05668-x